Inflammatory Disease

News Inflammatory Disease

• BGU researchers have discovered how prolonged exposure to stress can increase the risk of autoimmune diseases

  Ben-Gurion University of the Negev researchers have proven that chronic stress increases the susceptibility to an autoimmune disease similar to multiple sclerosis, which is characterized by damage to the nervous system in the brain. The researchers, Dr. Idan Harpaz and Prof. Alon Monsonego, in conju more

• Researchers pinpoint how trees play role in smog production

  After years of scientific uncertainty and speculation, researchers at the University of North Carolina at Chapel Hill show exactly how trees help create one of society's predominant environmental and health concerns: air pollution. It has long been known that trees produce and emit isoprene, an abun more

• After age 18, asthma care deteriorates

  It is widely accepted that medical insurance helps older adults with chronic health problems to receive better care. But what about young adults between the ages of 18 and 25, a demographic that also tends to have the lowest levels of health insurance coverage? In what may be the first study to meas more

White papers Inflammatory Disease

• Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications
  

  Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diagnostics more

• Quantitative Detection of Legionella pneumophila in Water Samples: Assay Transfer to the LightCycler® 480 Real-Time PCR System
  

  An assay to detect and quantify Legionella spp. in water samples was successfully transferred from a capillary-based LightCycler® Instrument to the novel multiwell plate-based LightCycler® 480 System. A previously described protocol was easily adapted by modifying the fluorescent label of the detection probe to match the filter set of the LightCycler® 480 Instrument. While reproducibility and analytical sensitivity of the assay were found to be comparable on both systems, the novel plate-based instrument allowed for higher sample throughput and reduced assay time per sample. more

Publications Inflammatory Disease

• Endothelial heterogeneity and adhesion molecules N-glycosylation: Implications in leukocyte trafficking in inflammation

  Inflammation is a major contributing element to a host of diseases with the interaction between leukocytes and the endothelium being key in this process. Much is understood about the nature of the adhesion molecule proteins expressed on any given leukocyte and endothelial cell that modulates adhesi more

• Resequencing and fine-mapping of the chromosome 12q13-14 locus associated with multiple sclerosis refines the number of implicated genes

  Multiple sclerosis (MS) is a common chronic inflammatory disease of the central nervous system. Susceptibility to the disease is affected by both environmental and genetic factors. Genetic factors include haplotypes in the histocompatibility complex (MHC) and over 50 non-MHC loci reported by genome more

• Costs and quality of life in multiple sclerosis patients with spasticity

  Background The resource use and health‐related quality of life (HRQoL) of patients with multiple sclerosis (MS) spasticity are not well known. The purpose of this study was to obtain estimates of resource utilization, costs, and HRQoL, for patients with different levels of MS spasticity in south more

Market studies Inflammatory Disease

• BIOQUAL, Inc. - Strategic SWOT Analysis Review

  BIOQUAL, Inc. (Bioqual) is a public traded, research, development and consulting company and is engaged in providing quality research, development and consulting services to Government and commercial contract clients. The company is accredited by the association for the assessment and accreditation more

• Multiple Sclerosis – Pipeline Review, H2 2012

  Introduction Global Markets Direct’s, 'Multiple Sclerosis - Pipeline Review, Global Markets Direct’s, 'Multiple Sclerosis - Pipeline Review, H2 2012', provides an overview of the indication’s therapeutic pipeline. This report provides information on the therapeutic development for Multiple Scleros more

• Relapsing Remitting Multiple Sclerosis (RRMS) – Pipeline Review, H2 2012

  Introduction Global Markets Direct’s, 'Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline Review, H2 2012', provides an overview of the indication’s therapeutic pipeline. This report provides information on the therapeutic development for Relapsing Remitting Multiple Sclerosis (RRMS), comple more

Websites Inflammatory Disease