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Declining biodiversity may be contributing to the rise of asthma, allergies, and other chronic inflammatory diseases among people living in cities worldwide, a Finnish study suggests. Emerging evidence indicates that commensal microbes inhabiting the skin, airway, and gut protect against inflammator more
Limited awareness about the disease and its overall occurrence and progression among end-users is hampering the European multiple sclerosis (MS) market. This is being exacerbated by the limited availability of accurate diagnostic tools. There is, therefore, an immediate need for innovative and enhan more
Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells that due to a viral infection present non-self peptides at their surface. In more
Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diagnostics more
An assay to detect and quantify Legionella spp. in water samples was successfully transferred from a capillary-based LightCycler® Instrument to the novel multiwell plate-based LightCycler® 480 System. A previously described protocol was easily adapted by modifying the fluorescent label of the detection probe to match the filter set of the LightCycler® 480 Instrument. While reproducibility and analytical sensitivity of the assay were found to be comparable on both systems, the novel plate-based instrument allowed for higher sample throughput and reduced assay time per sample. more
Hawkes CH, Chawda S, Derakshani S, Muhammed N, Visentin E, Boniface D. MRI and visual‐evoked potentials in partners of multiple sclerosis patients. Acta Neurol Scand: 2012: 125: 424–430. © 2011 John Wiley & Sons A/S. Objective – Some epidemiological evidence, particularly concerning the role more
Abstract Aim: We examined the electrophysiological properties of reverse‐mode Na+/Ca2+ exchange (NCX) in mouse airway smooth muscle (ASM), assessing its contributions to regulation of [Ca2+], and its expression in acute and chronic airway hyperresponsiveness (AHR). Methods: Membrane curre more
Abstract With the establishment of routine virus load (DNAemia) screening for Human adenovirus (HAdV) and Cytomegalovirus (CMV) in post‐transplant care quality standards for quantitative PCR‐assays are increasing. Established real‐time PCR assays were improved with a fully automated DNA‐extractio more
BIOQUAL, Inc. (Bioqual) is a public traded, research, development and consulting company and is engaged in providing quality research, development and consulting services to Government and commercial contract clients. The company is accredited by the association for the assessment and accreditation more
Introduction Global Markets Direct’s, 'Asthma - Pipeline Review, H1 2012', provides an overview of the Asthma therapeutic pipeline. This report provides information on the therapeutic development for Asthma, complete with latest updates, and special features on late-stage and discontinued projects more
Introduction Global Markets Direct’s, 'Multiple Sclerosis - Pipeline Review, H1 2012', provides an overview of the Multiple Sclerosis therapeutic pipeline. This report provides information on the therapeutic development for Multiple Sclerosis, complete with latest updates, and special features on more
Contact Us Business Development Future Products Lead Product Target Pre-clinical Summary Clinical Studies Technology Team Management Team Board of Directors Scientific Advisors Home News & Events Leadership in Respiratory Disease Therapy Altair Therapeutics, Inc. is a biopharmaceutical company devel more
Contact | FAQ | Site Map About – Vision – Management – The Board – Pharmaceutical Partners – Investors – Business Strategy – Corporate Governance – Company FAQ – Contact LNA Drug Platform – Drug Discovery Engine – microRNA – mRNA – Publications Product Pipeline – Drug Candidates Intellectual Pro more
Inflammation is a defense mechanism of the body to protect it from infection and injury. The inflammatory response is started by white blood cells releasing defense molecules to remove injurious stimuli such as damaged cells, pathogens or irritants. Redness, pain, swelling, heat and loss of more
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Pelvic inflammatory disease Pelvic inflammatory disease (or disorder) (PID) is a generic term for inflammation of the female uterus , fallopian tubes , and/or ovaries as it progresses to scar formation with adhesions to nearby tissues and org ... more
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