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News GSK

• New hope in fight against multi-resistant germs

  An increasing number of bacteria is evolving antibiotic resistance. Much-feared representatives of this steadily growing group include Staphylococci strains. At this point, multi-resistant forms of the bacterium Staphylococcus aureus - the "hospital germ" known commonly by its acronym, MRSA - can on more

• Priaxon enters collaboration with GSK on Protein-Protein-Interactions

  Priaxon announced a collaboration with GlaxoSmithKline (GSK) to research and develop small molecule modulators of protein-protein-interactions. Priaxon will provide its innovative and proprietary small molecule drug discovery expertise which is particularly suited to investigating the modulation of more

• Prosensa Announces Progress on Exon Skipping Compounds for the Treatment of Duchenne Muscular Dystrophy

  Prosensa has selected clinical candidates for two more compounds for the treatment of Duchenne muscular dystrophy (DMD) and has been granted orphan drug designation for two additional DMD compounds in its pipeline.Prosensa identified suitable oligonucleotide candidates for PRO052 and PRO055, designe more

Publications GSK

• Group II Metabotropic Glutamate Receptor Agonist Ameliorates MK801-Induced Dysfunction of NMDA Receptors via the Akt|[sol]|GSK-3b Pathway in Adult Rat Prefrontal Cortex

  Group II Metabotropic Glutamate Receptor Agonist Ameliorates MK801-Induced Dysfunction of NMDA Receptors via the Akt/GSK-3b Pathway in Adult Rat Prefrontal Cortex Neuropsychopharmacology 38, 1141 (May 2013). doi:10.1038/npp.2013.36 Authors: Dong Xi, Yan-Chun Li, Melissa A Sny more

• Understanding the relationship between GSK-3 and Alzheimer’s disease: a focus on how GSK-3 can modulate synaptic plasticity processes

  Originally discovered because of its role in the regulation of glucose metabolism, GSK-3 is now widely recognized as a crucial player in many cellular functions. Control of GSK-3 activity occurs by complex mechanisms that are each dependent upon specific signaling pathways. Furthermore, GSK-3 dysfun more

• Distinct Effects of Ligand-Induced PDGFR{alpha} and PDGFR{beta} Signaling in the Human Rhabdomyosarcoma Tumor Cell and Stroma Cell Compartments

  Platelet-derived growth factor receptors (PDGFR) α and β have been suggested as potential targets for treatment of rhabdomyosarcoma, the most common soft tissue sarcoma in children. This study identifies biologic activities linked to PDGF signaling in rhabdomyosarcoma models and human sample collect more

Market studies GSK

• Type 2 Diabetes - Global Drug Forecasts and Treatment Analysis to 2020

  Introduction GlobalData, the industry analysis specialist, has released its new report, “Type 2 Diabetes - Global Drug Forecasts and Treatment Analysis to 2020”. The report is an essential source of information and analysis on the global type 2 diabetes therapeutics market. The report provides comp more

• Belgium Pharmaceuticals and Healthcare Report Q3 2012

  BMI View: Belgium’s rapidly ageing population, traditionally high per capita consumption of medicines and a well-developed healthcare system will combine to continue providing substantial commercial opportunities for pharmaceutical sector players. However, given the need for fiscal austerities in re more

• Kazakhstan Pharmaceuticals and Healthcare Report Q3 2012

  BMI View: Kazakhstan continues to stand out among the pharmaceutical markets of Central Asia in terms of openness to foreign investment in the pharmaceutical industry. The country’s expected accession to the World Trade Organisation could come as early as the end of 2012 and this will continue to dr more

Websites GSK