Growth Factors

Companies Growth Factors

PeproTech GmbH, Germany

PeproTech was established in 1988 by a group of scientists who focussed their efforts on the development and production of recombinant cytokines for life-science research. Today, PeproTech is a world leader in supplying high quality cytokine products including more than 350 E. coli, insect, and mamm more

Biomol GmbH, Germany

Biomol GmbH offers antibodies, enzymes, bioactive lipids, microarrays and reagents for biomedical research. Our focus is on cellular regulation and signal transduction. Together with our partners, we also provide a variety of specialized kits for drug discovery. more

CellGenix GmbH, Germany

CellGenix GmbH is a biopharmaceutical company active in the field of cellular therapies and regenerative medicine. The company develops, manufactures and markets cell therapy products and high-quality reagents for ex vivo cell culture. CellGenix is a leading supplier of GMP (Good Manufacturing Prac more

Catalogues Growth Factors

MACS® Cytokines: recombinant cytokines & growth factors

At Miltenyi Biotec, high production standards, up to GMP, ensure constant high quality. A broad choice of cytokines for demanding applications make up our portfolio more

News Growth Factors

• Genetically active nano-calcium phosphate paste for bioactive bone grafts

  A genetically active nanoparticle calcium phosphate bone paste has been developed by scientists working in Germany, who claim that the material can act as a gene-delivery agent as well as a biodegradable bone graft. Calcium phosphates make up the majority of synthetic bone substitution materials, ow more

• Enhanced treatment of brain tumors

  Glioblastoma is regarded as the most malignant form of brain tumor. In many cases, neurosurgeons are not able to remove such tumors completely because of the risk of destroying too much brain tissue in the process. Moreover, it is often impossible to identify all the fine extensions by which the tum more

• UF medicinal chemists modify sea bacteria byproduct for use as potential cancer drug

  University of Florida researchers have modified a toxic chemical produced by tiny marine microbes and successfully deployed it against laboratory models of colon cancer.Writing in ACS Medicinal Chemistry Letters, UF medicinal chemists describe how they took a generally lethal byproduct of marine cya more

White papers Growth Factors

• High sensitive detection of follistatin by Imperacer®: an initial study on the way to analytical gene-doping tests
  

  For the understanding of interactions in the muscle-growth directing myostatin-pathway and therefore also for the establishment of high sensitive detection strategies for gene-doping, detailed studies of protein concentration levels in biological matrices and appropriate highly sensitive analytic techniques for quantitative monitoring of these biomarkers are required. In this work, the development of a high sensitive assay for follistatin based on the Imperacer® technology is described. The quantification limit in human serum was found at 60 pg/ml in only 6 µl sample volume. With this initial assay we demonstrate the first application in a set of analytical tests for a high sensitive myostatin pathway related profiling. more

• Transfection of Human Tooth-Specific Lineage Cells with FuGENE® HD Transfection Reagent
  

  Similar to other epithelial appendages, teeth form through reciprocal signaling interactions between the ectodermally derived dental epithelium and the mesenchyme. These signaling interactions program enamel matrix-secreting ameloblasts and dentin-forming odontoblasts. To study the signaling network involved in odontogenesis, we co-cultured primary human fetal dental epithelial cells and dental pulp cells to reconstitute the reciprocal signaling. more

• Characterizing Biotherapeutics with HPLC
  

  As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmaceutical to approval at the regulatory agencies. The introduction of the first so-called biosimilars in Europe further increased the demand for highly efficient analysis methods. The continuous development of new stationary phases for the common modes of biochromatography, such as size exclusion, ion exchange and hydrophilic interaction chromatography support biochemists in increasing lab productivity and establishing high-throughput HPLC analysis not only for small molecules but also for large biopolymers more

Publications Growth Factors

• Overexpression of Sulf2 in idiopathic pulmonary fibrosis

  Previously, we have shown that heparan sulfate (HS) 6-O-endosulfatase 1 (Sulf1) is a transforming growth factor-β1 (TGF-β1)-responsive gene in normal human lung fibroblasts and functions as a negative feedback regulator of TGF-β1 and that TGF-β1 induces the expression of Sulf1 as well as that of th more

• Controlled delivery of mesenchymal stem cells and growth factors using a nanofiber scaffold for tendon repair

  Publication date: June 2013 Source:Acta Biomaterialia, Volume 9, Issue 6 Author(s): C.N. Manning , A.G. Schwartz , W. Liu , J. Xie , N. Havlioglu , S.E. Sakiyama-Elbert , M.J. Silva , Y. Xia , R.H. Gelberman , S. Thomopoulos Outcomes after tendon repair are often unsatisfactory, desp more

• Bioactive silicate materials stimulate angiogenesis in fibroblast and endothelial cell co-culture system through paracrine effect

  Publication date: June 2013 Source:Acta Biomaterialia, Volume 9, Issue 6 Author(s): H. Li , J. Chang Angiogenesis is critical in tissue engineering, and bioceramic-induced angiogenesis has been reported. However, the role of other types of cells such as fibroblasts in this bioceramic-induced more

Market studies Growth Factors

• Ovarian Cancer Therapeutics - Global Drug Forecasts and Treatment Analysis 2020

  Introduction GlobalData, the industry analysis specialist, has released its new report, “Ovarian Cancer Therapeutics - Global Drug Forecasts and Treatment Analysis 2020”. The report is an essential source of information and analysis on the global ovarian cancer therapeutics market. The report provi more

• Pharmaceutical Pricing and Reimbursement in Oncology - Payer Pressure to Justify Premium Pricing of Novel Agents, Pushing Companies to Risk-Sharing Modalities

  GBI Research, leading business intelligence provider, has released its latest research report, entitled “Pharmaceutical Pricing and Reimbursement in Oncology - Payer Pressure to Justify Premium Pricing of Novel Agents, Pushing Companies to Risk-Sharing Modalities”. It provides a comprehensive overvi more

• Immune-tree International, Inc. - Strategic SWOT Analysis Review

  Immune-tree International, Inc. (Immune tree)specializes in the development and manufacture of colostrum-based health food products. Colostrum is a pre-milk fluid which is made up of all 87 natural anti-aging growth factors, over 95+ immune factors, vitamins/minerals/enzymes, and essential fatty aci more

Websites Growth Factors