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• A Mystery Solved: How Genes Are Selectively Silenced

  Cells have to use their resources economically. Therefore, they read only those genes which are needed at a given moment, while the others are chemically labeled and, thus, selectively turned off. Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now been more

• Largest ever epigenetics project launched

  One of the most ambitious large-scale projects in Human Genetics has been launched: Epitwin will capture the subtle epigenetic signatures that mark the differences between 5,000 twins on a scale and depth never before attempted, providing key therapeutic targets for the development of drug treatment more

• Gene scan finds link across array of childhood brain disorders

  Mutations in a single gene can cause several types of developmental brain abnormalities that experts have traditionally considered different disorders. With support from the National Institutes of Health, researchers found those mutations through whole exome sequencing. "This is going to change the more

Publications GeneScan

• Response of rice to insect elicitors and the role of OsJAR1 in wound and herbivory‐induced JA‐Ile accumulation

  Abstract Plants produce jasmonic acid (JA) and its amino acid conjugate, jasmonoyl‐L‐isoleucine (JA‐Ile) as major defense signals in response to wounding and herbivory. In rice, JA and JA‐Ile rapidly increased after mechanical damage, and this increase was further amplified when the wounds were more

• Graphical modelling of molecular networks underlying sporadic Inclusion Body Myositis

  Here we present a novel statistical methodology that allows us to analyze gene expression data that have been collected from a number of different cases or conditions in a unified framework. Using a Bayesian nonparametric framework we develop a hierarchical model wherein genes can maintain a shared more

• [News of the Week] Around the World

  In science news around the world, the number of reported H7N9 infections is rising in China, the U.S. Supreme Court heard arguments asking if human genes can be patented, a letter DNA-discoverer Francis Crick wrote to his son sold for $5.3 million at auction, and more. more

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