Garner Aldehyde

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• Pieris Signs Broad Collaboration with Sanofi-Aventis and Sanofi Pasteur to Develop Anticalin Therapeutics

  Pieris AG announced the signature of a collaboration and license agreement with both Sanofi-Aventis and Sanofi Pasteur, the vaccines division of the sanofi-aventis Group, under which Pieris will apply its proprietary Anticalin technology to discover novel Anticalin drugs against multiple targets, wi more

• AMT receives orphan drug designation from the U.S. Food and Drug Administration Duchenne Muscular Dystrophy gene therapy

  Amsterdam Molecular Therapeutics (AMT) Holding N.V. announced that the U.S. Food and Drug Administration (FDA) has designated AMT-080, a gene therapy for Duchenne muscular dystrophy (DMD) as an orphan drug. In October 2009, the Committee for Orphan Medical Products of the European Medicines Agency g more

• LAB Research launches new investigational model for large US based biotech

  LAB Research Inc. announced that it has recently completed development of a novel drug investigation model focused on biodistribution and pharmacokinetic of biologics. LAB Research's strategy combines its expertise in pharmacology, infusion, surgery and minipigs research and could potentially revo more

Publications Garner Aldehyde

• Spreading of Heterochromatin Is Limited to Specific Families of Maize Retrotransposons

  by Steven R. Eichten, Nathanael A. Ellis, Irina Makarevitch, Cheng-Ting Yeh, Jonathan I. Gent, Lin Guo, Karen M. McGinnis, Xiaoyu Zhang, Patrick S. Schnable, Matthew W. Vaughn, R. Kelly Dawe, Nathan M. Springer Transposable elements (TEs) have the potential to act as controlling elements more

• Crystal structure of the human PRMT5:MEP50 complex [Biochemistry]

  Protein arginine methyltransferases (PRMTs) play important roles in several cellular processes, including signaling, gene regulation, and transport of proteins and nucleic acids, to impact growth, differentiation, proliferation, and development. PRMT5 symmetrically di-methylates the two-terminal ω-g more

• Opioid receptor characterisation of neuronally stimulated isolated human vas deferens

  Rodent vas deferens is routinely used as a native tissue preparation to assess opioid pharmacology of new compounds. The aim of this study was to investigate the effects of a selected number of opioid compounds in the human vas deferens. Stable contractions to electrical field stimulation (EFS) were more

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