Fluorescence

Products Fluorescence

The top class multi-mode reader for assay development

No compromise – Tecan’s Infinite® M 1000 PRO is the top class multi-mode reader for assay development - speed, high flexibility, outstanding results more

Software Fluorescence

Free-of-charge Shimadzu News App for iPhone® and iPod® touch ‘Online’ virtually anywhere on earth

Shimadzu, one of the worldwide leading manufacturers in analytical instrumentation, has broken new grounds with the introduction of its News App for more

News Fluorescence

• New molecular probes that shed light on biological systems

  Reactive sulfur species have attracted increasing attention in biomedical research because of their involvement in a variety of physiological functions. There has been a rising interest in sulfane sulfur compounds – compounds which contain sulfur atoms with six valence electrons, but no charge – bec more

• Dying Brightly

  Programmed cell death, or apoptosis, occurs tens of millions of times every day in every human body. Researchers in South Korea have devised an easy method to detect apoptotic cells by fluorescence, as they report in Chemistry—An Asian Journal. Their method makes it easier to detect improper biologi more

• Proteins barge in to turn off unneeded genes and save energy

  The sorcerer's apprentice started a water-carrying system, but couldn't stop it, and soon he was up to his neck in water, and trouble. Living cells have a better design: When they activate a gene, they have a system in reserve to turn it off. The cell does not want to waste energy making proteins it more

White papers Fluorescence

• Efficient Transfection of 293T Cell Line with Lentiviral Vectors Using FuGENE® HD Transfection Reagent
  

  Lentiviral vectors have become a powerful tool for gene transfer and genetic manipulation in research. Efficiency of the transfection reagent is most critical to getting a high-titer lentiviral recombinant virus. Here, we show that FuGENE® HD Transfection Reagent can be used to transfect 293T cells with lentiviral vectors with high efficiency. more

• Enzyme Kinetic Measurements for a Combinatorial Library of Inhibitors of Pseudomonas Elastase
  

  Pseudomonas elastase (LasB) is a key drug target in various chronic and intractable infections. A library of 160 potential, in-house synthesised, elastase inhibitors were screened using a fluorescence assay with the internally quenched substrate Abz-Ala-Gly-Leu-Ala-Nba. Enzymatic kinetic measurements were done on a FLUOstar OPTIMA and Km and Vmax values were calculated for each inhibitor using the MARS Data Analysis software more

• Real-Time PCR Quantification of Plant miRNAs Using Universal ProbeLibrary Technology
  

  MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (18-25 nt in length) that are processed from larger hairpin precursors. Both plant and animal genomes encode miRNAs, and to date, there are over 4000 mature miRNA transcripts annotated. Although miRNAs represent a relatively abundant class of transcripts, their expression levels vary greatly among species and tissues. Less abundant miRNAs routinely fail detection using technologies such as cloning, northern hybridization and microarray analysis. Here, we present a real-time quantification method for accurate, sensitive, and economical detection of plant miRNAs based upon the stem-loop RT primer approach using an miRNA-specific primer coupled with a stem-loop specific Universal ProbeLibrary (UPL) probe. This approach represents a highly specific, sensitive, and easy-to-apply system to detect miRNAs. more

Publications Fluorescence

• Oxidation of tyrosine photoinduced by pterin in aqueous solution

  Abstract Pterins, heterocyclic compounds widespread in biological systems, accumulate in the skin of patients suffering from vitiligo, a chronic depigmentation disorder. Pterins have been previously identified as good photosensitizers under UV‐A irradiation. In this work, we have investigated th more

• Dynamin contributes to cytokinesis by stabilizing actin filaments in the contractile ring

  Dynamin has been proposed to play an important role in cytokinesis, although the nature of its contribution has remained unclear. Dictyostelium discoideum has five dynamin‐like proteins: DymA, DymB, DlpA, DlpB and DlpC. Cells mutant for dymA, dlpA or dlpB presented defects in cytokinesis that resu more

• {beta}1 Integrin Targeting Potentiates Antiangiogenic Therapy and Inhibits the Growth of Bevacizumab-Resistant Glioblastoma

  Antiangiogenic therapies like bevacizumab offer promise for cancer treatment, but acquired resistance, which often includes an aggressive mesenchymal phenotype, can limit the use of these agents. Upregulation of β1 integrin (ITGB1) occurs in some bevacizumab-resistant glioblastomas (BRG) whereby, me more

Market studies Fluorescence

• Fluorotechnics Limited (FLS) - Financial and Strategic SWOT Analysis Review

  Fluorotechnics Limited (Fluorotechnics) is a pharmaceutical and healthcare company engaged in developing consumables and small equipment for scientists to better measure biological processes using fluorescence. The company's products are used globally by its customers in research, quality control an more

• Da An Gene Co., Ltd. (002030) - Financial and Strategic SWOT Analysis Review

  Da An Gene Co., Ltd. (Da An Gene) is a medical company engaged in the research, development, manufacture and marketing of biomedicine, which is utilized in molecular biology markets. It is also involved in the development and application of gene diagnostic technologies and related products. The pro more

• Imaging Diagnostic Systems, Inc. (IMDS) - Financial and Strategic SWOT Analysis Review

  Imaging Diagnostic Systems, Inc. (IDSI) is a development stage medical technology company, which commercializes medical imaging equipment. The company is engaged in the development and testing of a Computed Tomography Laser Breast Imaging System (CT Laser Mammography or CTLM) used for detecting brea more

Websites Fluorescence