Field Flow Fractionation

Companies Field Flow Fractionation

Postnova Analytics GmbH, Germany

Leading Manufacturer of Systems and Services for Field-Flow Fractionation and Light Scattering used for the Separation and Characterization of Biopolymers, Protein Aggregates and Nanoparticles. Chromatography Supplies and Consumables for GPC, SEC, HPLC and CE. more

Products Field Flow Fractionation

Eclipse DUALTEC - the new dimension in Flow-FFF

The new Eclipse DUALTEC brings high-end separation technology to your lab. It allows the standardization and highest reproducibility more

Standalone dynamic light scattering detection with cuvettes or with platereader

Revolutionize your performance by transforming your conventional, batch dynamic light scattering system into the stable, automated DynaPro Plate Reader more

Multi-angle light scattering detector for the measurement of absolute molecular weight and size

Wyatt's revolutionary DAWN HELEOS II Multi-Angle Light Scattering (MALS) Detector can incorporate both MALS and QELS into a single unit more

News Field Flow Fractionation

• Malvern Instruments and Postnova Analytics co-operate to deliver combined solution for characterizing challenging particulate systems

  Malvern Instruments and Postnova Analytics have announced that they are co-operating to deliver the combined FFF (Field-Flow Fractionation) and DLS (Dynamic Light Scattering) solutions that today provide critical insight when characterizing a number of challenging particulate systems. Such systems i more

White papers Field Flow Fractionation

• Characterizing Biotherapeutics with HPLC
  

  As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmaceutical to approval at the regulatory agencies. The introduction of the first so-called biosimilars in Europe further increased the demand for highly efficient analysis methods. The continuous development of new stationary phases for the common modes of biochromatography, such as size exclusion, ion exchange and hydrophilic interaction chromatography support biochemists in increasing lab productivity and establishing high-throughput HPLC analysis not only for small molecules but also for large biopolymers more

• Field-Flow Fractionation - The Universal Separation Principle for Particle and Macromolecule Characterization
  

  High molecular weight polymers, bio molecules or particles in a range of a few nanometers up to several microns are more and more important in science and technology. Many applications are based on the specific properties of these materials. For this reason, an exact knowledge of the molar mass or particle sizes distribution is essential for later application as well as for optimization of the production processes or quality control. In addition the knowledge about the chain structure of macromolecules or biopolymers as well as about the shape of particles is often necessary. For this reason those samples, which often can be very complex systems, have to be separated according to parameters such as e.g. hydrodynamic volume or molecular weight. After the separation process the resulting narrow dispersed fractions are detected with different techniques. more

• Characterization of micelles and liposomes using the Eclipse AF4 separation system coupled to a DAWN HELEOS II MALS detector
  

  Micelles and liposomes can serve as vehicles used to solubilize and carry bioactive compounds to their site of action, thus increasing their bioavailability. First experience has been made using vitamins and enzymes as functional food additives. Moreover, micelles could be useful to deliver drugs to a defined site of action, thus reducing frequently occurring side effects of systemic drug administration. Micelles are true nano-materials with a size range of 10 to 30 nm in diameter. Ideally, they should have a narrow size distribution. Furthermore, they have to be stable and should release their active compound only in the target region. Characterization of the micelle suspensions is vital to guarantee these properties and has to cover several aspects. One important point is size distribution, which has to be determined with high resolution more

Publications Field Flow Fractionation

• Hsp70 silencing with siRNA in nanocarriers enhances cancer cell death induced by the inhibitor of Hsp90

  Publication date: Available online 10 April 2013Source:European Journal of Pharmaceutical Sciences Author(s): Mirela Matokanovic , Karmela Barisic , Jelena Filipovic-Grcic , Dusica Maysinger Inducers of heat shock protein 70 (Hsp70) commonly promote cancer cell viability whereas inhibitors o more

• Asymmetric Flow Field-Flow Fractionation with Multiangle Light Scattering Detection for Characterization of Cellulose Nanocrystals

  Cellulose nanocrystals (CNCs) were analyzed by asymmetric flow field-flow fractionation (AF4) coupled with multiangle light scattering (MALS) detection. Small fractions were collected from the output of the AF4 apparatus for investigation by transmission electron microscopy (TEM). The influence of C more

• Effect of structurally different microbial homoexopolysaccharides on the quality of gluten-free bread

  The effect of structurally different bacterial homoexopolysaccharides on gluten-free bread quality and their properties to act as hydrocolloids was investigated. Furthermore, exopolysaccharides (EPS) were analyzed structurally by asymmetrical flow field flow fractionation and methylation analysis. B more

Websites Field Flow Fractionation