Expression

Companies Expression

CCS Cell Culture Service GmbH, Germany

CCS generates stably transfected cell lines for cell based drug screening and produces recombinant proteins from mammalian and insect cells. more

CCS Cell Culture Service, Inc., USA

We Make The Cells! The use of cell based assays for drug screening brings about the challenge of in-time cell production and scale-up. As a flexible external cell culture unit CCS supplies starting material for advanced screening and makes screening faster and more efficient. Within few years CCS ha more

Products Expression

Quality for PCR: Highly-active Taq polymerase and mastermixes

PCR reagents for standard use and special PCR applications. Highly-active, robust PCR reagents for routine use more

News Expression

• Researchers discover master regulator in cancer metastasis
  

  In the process of metastasis, the movement of cancer cells to different parts of the body, a specific master regulator gene plays a central role: a transcription factor named Sox4 activates a sequence of genes and triggers the formidable process. This finding is reported by researchers from the Univ more

• Laminopathies: Key components in the disease mechanism identified

  Laminopathies are hereditary diseases that affect mainly the muscle tissue. These diseases include for example Emery-Dreifuss Muscular dystrophy, dilated cardiomyopathy, limb-girdle muscular dystrophy and Hutchison-Gilford progeria syndrome. The underlying defect in these diseases is mutation in the more

• Protein signal is crucial for accurate control of insect size

  Two independent groups of researchers have identified a hormone that is responsible for keeping the growth and development of insects on track. The results, which are reported in Science, suggest that Dilp8 provides an important signal to slow body growth and delay insect development. This braking e more

White papers Expression

• Transfecting Mouse Fibroblast NIH 3T3 Cells with Lipid Reagents - A Comparative Study
  

  Prior to the advent of transfection lipids, mouse fibroblast NIH 3T3 cells were essentially untransfectable and other methods such as retroviral gene delivery had to be employed to circumvent this problem. Although retroviruses can be used for transgene expression in 100% of cells, the expression is often low. Additionally, NIH 3T3 cells are traditionally used for cellular transformation studies, and creating oncogenic retroviruses is not ideal due to bio-safety concerns. Recently, lentivruses have been used for high gene expression in cells (up to 100%). However, this method causes even greater bio-safety concerns and requires updating culture facilities to bio-safety level 2+, resulting in a costly and time-consuming procedure. more

• New Products for Cell Culture Analysis from Roche Innovatis
  

  The Roche Innovats product line is now available from Roche Applied Sciences. Below is a short introduction to three Roche Innovatis product lines designed for the complete analysis of cell cultures, from the simple determination of cell concentration to complex cellular screening. More information about Roche Innovatis products will appear in future issues of Biochemica more

• A Rapid, Sample-Safe, Evaporative Technique for Preparation of DNA and Oligonucleotide Samples
  

  When working with DNA and oligo samples great care needs to be taken at every stage to ensure that degradation does not occur, and the highly potent samples are not contaminated. Use of state of the art concentration systems can significantly speed up concentration rates, saving researchers time, and also eliminate potential sources of damage to samples more

Job offers Expression

• Leader Laboratory Mammalian Antibody Production (m/f)
  

  As one of the leading public biotech companies in Europe, we are committed to developing the medicines of the future. Building on our portfolio of innovative antibody technologies, we are actively pursuing new therapeutic approaches in close collaboration with the world‘s foremost pharmaceutical com more

Publications Expression

• Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

  The pubertal height growth spurt is a distinctive feature of childhood growth reflecting both the central onset of puberty and local growth factors. Although little is known about the underlying genetics, growth variability during puberty correlates with adult risks for hormone-dependent cancer and more

• Trans-splicing correction of tau isoform imbalance in a mouse model of tau mis-splicing

  Abnormal metabolism of the tau protein is central to the pathogenesis of a number of dementias, including Alzheimer's disease. Aberrant alternative splicing of exon 10 in the tau pre-mRNA resulting in an imbalance of tau isoforms is one of the molecular causes of the inherited tauopathy, FTDP-17. W more

• Increased levels of phosphoinositides cause neurodegeneration in a Drosophila model of amyotrophic lateral sclerosis

  The Vesicle-associated membrane protein (VAMP)-Associated Protein B (VAPB) is the causative gene of amyotrophic lateral sclerosis 8 (ALS8) in humans. Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by selective death of motor neurons leading to spasticit more

Market studies Expression

• Cloud Computing in Pharmaceutical Research and Development - Virtualization of Data through the Cloud Optimizes Next-Generation DNA Sequencing and Clinical Trials Data Management

  GBI Research, leading business intelligence provider has released its latest report, “Cloud Computing in Pharmaceutical Research and Development - Virtualization of Data through the Cloud Optimizes Next-Generation DNA Sequencing and Clinical Trials Data Management”, which provides insights into the more

• Clinical Trial Endpoints in Oncology - Inclusion of Surrogate Endpoints and Shorter Endpoints Will Ensure Faster Clinical Trials in Oncology

  GBI Research, the leading business intelligence provider, has released its latest research “Clinical Trial Endpoints in Oncology – Inclusion of Surrogate Endpoints and Shorter Endpoints will Ensure Faster Clinical Trials in Oncology”, which essentially provides insights into clinical trial endpoints more

• Mycenax Biotech Inc. (4726) - Financial and Strategic SWOT Analysis Review

  Mycenax Biotech Inc. (4726) - Financial and Strategic SWOT Analysis Review Summary Mycenax Biotech Inc. (Mycenax) is a biopharmaceutical company engaged in developing and manufacturing biopharmaceutical products derived from mammalian and microbial cells. Mycenax has three pipeline products, namel more

Websites Expression