Epilepsy

News Epilepsy

• Developmental delays in children following prolonged seizures

  Researchers from the UK determined that developmental delays are present in children within six weeks following convulsive status epilepticus (CSE)—a seizure lasting longer than thirty minutes. The study appearing in Epilepsia suggests that neurodevelopmental impairments continue to be present one y more

• One ion channel, many diseases

  A dysfunction of a certain Calcium channel, the so called P/Q-type channel, in neurons of the cerebellum is sufficient to cause different motor diseases as well as a special type of epilepsy. This is reported by the research team of Dr. Melanie Mark and Prof. Dr. Stefan Herlitze from the Ruhr-Univer more

• New probes for the brain

  Developing tiny probes for research and brain-related medical applications – that is the goal of the project NeuroSeeker, launched in February 2013 with a kick-off event in Leuven. The interdisciplinary project pools the expertise of ten partner institutions from Europe and Canada. The University of more

Publications Epilepsy

• Prickle1 is expressed in distinct cell populations of the central nervous system and contributes to neuronal morphogenesis

  Development of axons and dendrites constitutes a critical event in neuronal maturation and seems to require signaling through the planar cell polarity (PCP) pathway. Mutations in components of the PCP pathway lead to a spectrum of neurological phenotypes and disorders. For example, a missense mutat more

• Epileptogenic Q555X SYN1 mutant triggers imbalances in release dynamics and short-term plasticity

  Synapsin I (SynI) is a synaptic vesicle (SV) phosphoprotein playing multiple roles in synaptic transmission and plasticity by differentially affecting crucial steps of SV trafficking in excitatory and inhibitory synapses. SynI knockout (KO) mice are epileptic, and nonsense and missense mutations in more

• fosB-Null Mice Display Impaired Adult Hippocampal Neurogenesis and Spontaneous Epilepsy with Depressive Behavior

  fosB-Null Mice Display Impaired Adult Hippocampal Neurogenesis and Spontaneous Epilepsy with Depressive Behavior Neuropsychopharmacology 38, 1375 (June 2013). doi:10.1038/npp.2013.56 Authors: Noriko Yutsudo, Takashi Kamada, Kosuke Kajitani, Hiroko Nomaru, Atsuhisa Katogi, Yok more

Market studies Epilepsy

• D-Pharm Ltd. - Strategic SWOT Analysis Review

  D-Pharm LTD.(D-Pharm) is a specialty bio-pharmaceutical company. It is engaged in the design and development of innovative drugs for the treatment of the brain disorders. It has developed two unique platform technologies that generate lipid–like medicines which utilizes lipid specific mechanisms and more

• Epilepsy – Pipeline Review, H2 2012

  Introduction Global Markets Direct’s, 'Epilepsy - Pipeline Review, H2 2012', provides an overview of the Epilepsy therapeutic pipeline. This report provides information on the therapeutic development for Epilepsy, complete with latest updates, and special features on late-stage and discontinued pr more

• Germany Pharmaceuticals and Healthcare Report Q4 2012

  BMI View: While the Arzneimittelmarkt-Neuordnungsgesetz (AMNOG) legislation will compress drug company's revenue-earning opportunities in Germany, we believe the country will remain an attractive location to launch drugs in. In 2011, Germany's drug market was the fourth-largest globally, after the U more

Websites Epilepsy