Classification & external resources
Shy-Drager syndrome is a rare, progressively degenerative disease of the autonomic nervous system. It is named after Dr Milton Shy and Dr Glenn Drager, who identified this syndrome in 1960.
The American Autonomic Society and the American Academy of Neurology deprecated it as a disease entity in 1996, and existing cases were redefined as multiple system atrophy with autonomic phenomena. The name "Shy-Drager syndrome" is still used occasionally for multiple system atrophy when the primary symptoms are autonomic failure.
No definitive treatment currently exists. Medications used for Parkinson's disease have not shown to be useful. Treatments are generally geared to give symptomatic control, especially to maintain adequate blood pressure (adrenergic agonists, and mineralocorticoid analogs such as fludrocortisone).
- Johnny Cash (possible misdiagnosis of autonomic neuropathy)
- ^ synd/875 at Who Named It
- ^ Shy GM, Drager GA (1960). "A neurological syndrome associated with orthostatic hypotension: a clinical-pathologic study". Arch. Neurol. 2: 511–27. PMID 14446364.
- ^ (1996) "Consensus statement on the definition of orthostatic hypotension, pure autonomic failure, and multiple system atrophy". Neurology 46 (5): 1470. PMID 8628505.
|Nervous system pathology, primarily PNS (G50-G99, 350-359)|
|Nerve, nerve root|
and plexus disorders
|cranial nerve: V (Trigeminal neuralgia) - VII (Facial nerve paralysis, Bell's palsy, Melkersson-Rosenthal syndrome, Central seven) - XI (Accessory nerve disorder)|
nerve root and plexus: Brachial plexus lesion - Thoracic outlet syndrome - Phantom limb
mononeuropathy: Carpal tunnel syndrome - Ulnar nerve entrapment - Radial neuropathy - Causalgia - Meralgia paraesthetica - Tarsal tunnel syndrome - Morton's neuroma - Mononeuritis multiplex
and other disorders of the PNS
|Hereditary and idiopathic (Charcot-Marie-Tooth disease, Dejerine Sottas syndrome, Refsum's disease, Morvan's syndrome) - Guillain-Barré syndrome - Alcoholic polyneuropathy - Neuropathy|
|Diseases of myoneural junction|
|Myasthenia gravis - Primary disorders of muscles (Muscular dystrophy, Myotonic dystrophy, Myotonia congenita, Thomsen disease, Neuromyotonia, Paramyotonia congenita, Centronuclear myopathy, Nemaline myopathy, Mitochondrial myopathy) - Myopathy - Periodic paralysis (Hypokalemic, Hyperkalemic) - Lambert-Eaton myasthenic syndrome|
|Autonomic||Familial dysautonomia - Horner's syndrome - Multiple system atrophy (Shy-Drager syndrome, Olivopontocerebellar atrophy)|