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Renal ura handling is the part of renal physiology that deals with the reabsorption and secretion of urea.
Urea allows the body to create hyperosmotic urine (urine that has more ions in it--is "more concentrated"--than that same person's
blood plasma). Preventing the loss of water in this manner is important if the person's body needs to save water in order to maintain a suitable blood pressure or (more likely,) in order to maintain a suitable concentration of sodium ions in the blood plasma.
About half of the urea filtered (40%
) is normally found in the final urine, since there is more reabsorption than secretion along the  nephron.
It is regulated by
antidiuretic hormone, which controls the amount reabsorbed in the collecting duct system and secreted into the loop of Henle.
loop of Henle
Distal convoluted tubule
Collecting duct system
thin ascending limb
thick ascending limb
initial collecting tubule
cortical collecting ducts
medullary collecting ducts
reabsorption (% compared to filtered amount)
secretion (% compared to filtered amount)
electrical driving force (mV)
 +3  +15  -5 to +5  -40 
chemical driving force (mV)
electrochemical driving force (mV)
apical transport proteins
 unknwn transporter
basolateral transport proteins
Other reabsorption features
a b c d e f g h i j k l Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3. Page 791 ^ a b c d e Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3. Page 777
This article is licensed under the
GNU Free Documentation License. It uses material from the Wikipedia article "Renal_urea_handling". A list of authors is available in Wikipedia.
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