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Mitochondrial myopathy

**Mitochondrial myopathy**
*Classification & external resources*

Simplified structure of a typical mitochondrion
ICD-10	G71.3
MeSH	D017240

Mitochondrial myopathy are a type of myopathy associated with mitochondrial disease.

Examples include:

Myoclonic epilepsy and ragged-red fibers (MERRF)
- progressive myoclonic epilepsy
- clumps of diseased mitochondria accumulate in the subsarcolemmal region of the muscle fiber and appear as "ragged-red fibers" when muscle is stained with modified Gomori trichrome stain
- short stature

Kearns-Sayre syndrome (KSS)
- external ophthalmoplegia
- cardiac conduction defects
- sensory-neural hearing loss

Progressive external ophthalmoplegia (PEO)
- progressive ophthalmoparesis is the cardinal feature
- symptomatic overlap with many other mitochondrial myopathies

v • d • e Nervous system pathology, primarily PNS (G50-G99, 350-359)
Nerve, nerve root and plexus disorders	cranial nerve: V (Trigeminal neuralgia) - VII (Facial nerve paralysis, Bell's palsy, Melkersson-Rosenthal syndrome, Central seven) - XI (Accessory nerve disorder) nerve root and plexus: Brachial plexus lesion - Thoracic outlet syndrome - Phantom limb mononeuropathy: Carpal tunnel syndrome - Ulnar nerve entrapment - Radial neuropathy - Causalgia - Meralgia paraesthetica - Tarsal tunnel syndrome - Morton's neuroma - Mononeuritis multiplex
Polyneuropathies and other disorders of the PNS	Hereditary and idiopathic (Charcot-Marie-Tooth disease, Dejerine Sottas syndrome, Refsum's disease, Morvan's syndrome) - Guillain-Barré syndrome - Alcoholic polyneuropathy - Neuropathy
Diseases of myoneural junction and muscle	Myasthenia gravis - Primary disorders of muscles (Muscular dystrophy, Myotonic dystrophy, Myotonia congenita, Thomsen disease, Neuromyotonia, Paramyotonia congenita, Centronuclear myopathy, Nemaline myopathy, Mitochondrial myopathy) - Myopathy - Periodic paralysis (Hypokalemic, Hyperkalemic) - Lambert-Eaton myasthenic syndrome
Autonomic	Familial dysautonomia - Horner's syndrome - Multiple system atrophy (Shy-Drager syndrome, Olivopontocerebellar atrophy)

v • d • e Mitochondrial diseases
Myopathies	MELAS - MERRF - KSS - PEO
Other	DAD - Friedreich's ataxia - LHON - Leigh's - NARP - MNGIE - PCD - PDHA - Pearson syndrome

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Mitochondrial_myopathy". A list of authors is available in Wikipedia.