Manchester score

Manchester score is an indicator of prognosis in small cell lung cancer.^[1][2] It is calculated from a number of physical and biochemical markers.

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A patient with small cell lung cancer scores one point for each of the following: -

• Serum lactate dehydrogenase exceeds the upper limit of the reference range.
• Serum sodium concentration less than 132 mmol/l.
• Serum alkaline phosphatase over one-and-a-half times the upper limit of the reference range.
• Serum bicarbonate less than 24.
• Karnofsky performance status less than 60.
• Extensive stage disease.

Prognosis

References

1. ^ Cerny, T; Blair V, Anderson H et al. (1987). "Pretreatment prognostic factors and scoring system in 407 small-cell lung cancer patients". International Journal of Cancer 39 (2): 146-149.
2. ^ Kawahara, Masaaki; Masahiro Fukuoka, Nagahiro Saijo et al. (1996). "Prognostic factors and prognostic staging system for small cell lung cancer". Japanese Journal of Clinical Oncology 27 (3): 158-165. Oxford University Press. ISSN: 0368-2811.
3. ^ Maestu, I; Pastor M, Gómez-Codina J et al. (Jun 1997). "Pretreatment prognostic factors for survival in small-cell lung cancer: a new prognostic index and validation of three known prognostic indices on 341 patients". Annals of Oncology 8 (6): 547-553.