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Jeryl Lynn are strains of mumps virus used in the Mumpsvax mumps vaccine made by Merck. The strains are named after Jeryl Lynn Hilleman. In 1963 Ms. Hilleman's father Dr. Maurice Hilleman, was leading efforts to produce a mumps vaccine for Merck. He cultured the Mumps virus from her throat, and in 1967 a vaccine was produced from this which is now widely used.
The Jeryl Lynn strains used in the manufacture of Mumpsvax later turned out to contain two distinguishable viral substrains, JL1 and JL2. Further research showed that the JL1 strain was preferentially selected by propagation in Vero and CEF cell cultures. The JL2 strain was preferentially selected by passage in embryonated chicken eggs.
In the U.S.A. the Jeryl Lynn strain-based vaccines supplanted the previous, killed virus, vaccine in 1978.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Jeryl_Lynn". A list of authors is available in Wikipedia.|