My watch list
With an accout for my.bionity.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
My watch list
My saved searches
My saved topics
Systematic (IUPAC) name
Formula C 15 H 22 O 3
Mol. mass 250.333 g/mol
Bioavailability Close to 100%
Metabolism Hepatic (CYP3A4)
Half life 1.5 hours
Excretion Renal 94% Feces 6%
Gemfibrozil is the generic name for an oral drug used to lower lipid levels. It belongs to a group of drugs known as fibrates. It is most commonly sold as the brand name, Lopid. Other brand names include Jezil and Gen-Fibro.
Reduce triglyceride levels
Reduce Very low density lipoprotein (VLDL) levels
Modest reduction of Low density lipoprotein (LDL) levels
Moderate increase in High density lipoprotein (HDL) levels
Nontherapeutic effects and toxicities
Increased incidence of gallstones
Hyperlipidemia (Type III): Gemfibrozil is the drug of choice for therapy.
Hypertriglyceridemia (Type IV): Gemfibrozil, though not as effective as niacin, is better tolerated.
Contraindications and Precautions
Gemfibrozil should not be given to these patients:
Gemfibrozil should be used with caution in these higher risk categories:
Biliary tract disease
Anticoagulants. Gemfibrozil potentiates the action of coumadin and indanedione anticoagulants.
Lovastatin. Risk of myopathy when gemfibrozil is given to patients receiving lovastatin.
This article is licensed under the
GNU Free Documentation License. It uses material from the Wikipedia article "Gemfibrozil". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE