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Coactivation is a process by which the transcription of RNA is increased. Proteins called coactivators are recruited to DNA-binding transcription factors through their activation domains and increase transcription by relaxing the chromatin structure to allow greater access to a gene or by bringing in components of the basal transcription complex needed for transcription to occur. Examples of coactivators are CBP, p300, Mediator and SWI/SNF.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Coactivation_(Transcription)". A list of authors is available in Wikipedia.|