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Brompheniramine (also known as Bromfed®, Bromfenex®, and Dimetane®) is an antihistamine drug of the propylamine class. It is commonly available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing. It is a first-generation antihistamine.
Brompheniramine works by acting as an antagonist of histamine H1 receptors. It also functions as a moderately effective anticholinergic agent, and is likely an antimuscarinic agent similar to other common antihistamines such as diphenhydramine.
Brompheniramine is metabolised via cytochrome P450 oxidase.
Its effects on the cholinergic system may include side-effects such as drowsiness, sedation, dry mouth, dry throat, blurred vision, and increased heart rate.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Brompheniramine". A list of authors is available in Wikipedia.|