EMBL

News EMBL

• Learning from the linker

  Mature cells can be reprogrammed to pluripotency and thus regain the ability to divide and differentiate into specialized cell types. Although these so-called induced pluripotent stem cells (iPS cells) represent a milestone in stem cell research, many of the biochemical processes that underlie repro more

• Flu fighters

  Savira pharmaceuticals GmbH, a spin-off of the European Molecular Biology Laboratory (EMBL), has signed a collaboration and license agreement with Roche, thus further strengthening the links between fundamental research and major pharmaceutical development companies.This partnership should promote t more

• New resource opens the door for enzyme research
  

  The European Molecular Biology Laboratory's European Bioinformatics Institute has launched the Enzyme Portal, a freely available resource for people who are interested in the biology of enzymes and proteins with enzymatic activity.The Enzyme Portal mines and displays data about proteins with enzymat more

White papers EMBL

• Improved Performance of the LightCycler®
  

  Real-time reverse transcription-PCR (RT-PCR) is con­sidered the method of choice for any experiments requiring­ sensitive, specific, and reproducible quantification of mRNA molecules of interest. It is an essential tool for basic research, molecular medicine, and biotechnology. more

• RealTime ready qPCR Assay Design and Configuration Portal Content
  

  The gene and transcript annotational content of the RealTime ready Configurator offers a combined view of three of the main gene annotation authorities. The positional information of the lab-tested RealTime ready assays regarding transcript or exon coverage is presented in a graphical overview and tabular format. Additional content provides a convenient and browsable entry point for target gene selection for cataloged as well as new assays that are developed on demand more

Publications EMBL

• The EBI enzyme portal

  The availability of comprehensive information about enzymes plays an important role in answering questions relevant to interdisciplinary fields such as biochemistry, enzymology, biofuels, bioengineering and drug discovery. At the EMBL European Bioinformatics Institute, we have developed an enzyme p more

• PTMcode: a database of known and predicted functional associations between post-translational modifications in proteins

  Post-translational modifications (PTMs) are involved in the regulation and structural stabilization of eukaryotic proteins. The combination of individual PTM states is a key to modulate cellular functions as became evident in a few well-studied proteins. This combinatorial setting, dubbed the PTM c more

• DELLY: structural variant discovery by integrated paired-end and split-read analysis

  Motivation: The discovery of genomic structural variants (SVs) at high sensitivity and specificity is an essential requirement for characterizing naturally occurring variation and for understanding pathological somatic rearrangements in personal genome sequencing data. Of particular interest are in more

Websites EMBL