Electroporation

Companies Electroporation

Eppendorf AG, Germany

Eppendorf is a leading life science company that develops and sells instruments, consumables, and services for liquid-, sample-, and cell handling in laboratories worldwide. Its product range includes pipettes and automated pipetting systems, dispensers, centrifuges, mixers, spectrometers, and DNA a more

News Electroporation

• Cellectis acquires assets from Cyto Pulse Sciences Inc.

  Cellectis has announced that it has acquired all the assets of Cyto Pulse Sciences Inc., a US-based company specializing in the development, manufacture and commercialization of electroporation technology and equipment. The transaction value of $2.2 million was paid in cash and closed on September more

• Cell Projects licenses Electroporation Technologies from Queen’s University, Canada

  Cell Projects (UK) has entered into a wide ranging commercial license and joint development agreement with Queen’s University, Kingston, Ontario, Canada, covering several new Electroporation platform technologies for Adherent and InSitu Cell Electroporation. The ground-breaking technology allows DN more

• Pharmexa and Ichor Medical Systems enter into an agreement to co-develop multiple DNA vaccines delivered by electroporation

  Pharmexa and Ichor have entered into an agreement to co-develop multiple DNA vaccines to combat important diseases of high unmet medical need. It is well recognized that in vivo electroporation is a promising means of enhancing the potency of DNA vaccines. The co-development programmes include a vac more

White papers Electroporation

• New Standard in Electrophysiology and Deep Tissue Imaging
  

  The function of nerve and muscle cells relies on ionic currents flowing through ion channels. These ion channels play a major role in cell physiology. One way to investigate ion channels is to use patch clamping. This method allows investigation of ion channels in detail and recording of the electric activity of different types of cells, mainly excitable cells like neurons, muscle fibres or beta cells of the pancreas. The patch clamping technique was developed by Erwin Neher and Bert Sakmann in the 1970s and 80s to study individual ion channels in living cells. In 1991 they received the Nobel Prize for Physiology and Medicine for their work. Today the patch clamping technique is one of the most important methods in the field of electrophysiology more

• HelpCorner - Gene Silencing
  

  more

• Fugene® HD Transfection Reagent: Superior Performance for Challenging Expression Studies
  

  The ability to efficiently introduce foreign molecules into cells constitutes an important tool in any laboratory and facilitates studies of gene regulation and protein function. A plethora of transfection methods have been developed for transfer of DNA into mammalian and animal cells. Those methods either utilize the physicochemical properties of the vector-carrier of the DNA or use mammalian viruses. In the first group of methods, some classic techniques are well-known, such as: calcium phosphate, DEAE-dextran, electroporation liposome-mediated delivery, direct microinjection/biolistic particle delivery, and non-liposomal multi-component reagents. Viral vector systems use both DNA (Adeno-) and RNA (Retro-, Lenti-) viruses. more

Publications Electroporation

• Anti-Bacterial Activity of Recombinant Human β-Defensin-3 Secreted in the Milk of Transgenic Goats Produced by Somatic Cell Nuclear Transfer

  by Jun Liu, Yan Luo, Hengtao Ge, Chengquan Han, Hui Zhang, Yongsheng Wang, Jianmin Su, Fusheng Quan, Mingqing Gao, Yong Zhang The present study was conducted to determine whether recombinant human β-defensin-3 (rHBD3) in the milk of transgenic goats has an anti-bacterial activity against Escheric more

• Therapeutic DNA Vaccination Using In Vivo Electroporation Followed by Standard of Care Therapy in Patients With Genotype 1 Chronic Hepatitis C

  Therapeutic DNA Vaccination Using In Vivo Electroporation Followed by Standard of Care Therapy in Patients With Genotype 1 Chronic Hepatitis C Molecular Therapy advance online publication, June 11 2013. doi:10.1038/mt.2013.119 Authors: Ola Weiland, Gustaf Ahlén, Helmut Diepolder, Mar more

• Irreversible electroporation and apoptosis in human liver cancer cells induced by nanosecond electric pulses

  Abstract The goal of this study was to assess the effect of nanosecond electric pulses on HepG2 human liver cancer cells. Electric pulses with a high strength of 10 kV/cm, duration of 500 ns and frequency of 1 Hz were applied to the cells. After delivery of electric pulses, apoptosis, intracell more

Websites Electroporation