Crohn's Disease

News Crohn's Disease

• Abbott's HUMIRA (Adalimumab) Approved in Europe for Severe Active Pediatric Crohn's Disease

  Abbott announced that the European Commission has approved HUMIRA® (adalimumab) for the treatment of pediatric patients aged 6 to 17 years with severe active Crohn's disease (CD) who failed, are intolerant to, or have contraindications to conventional therapy. With this approval, HUMIRA becomes the more

• Abbott's HUMIRA Approved in Europe for Expanded Treatment of Crohn's Disease (CD)

  Abbott announced that the European Commission (EC) has approved HUMIRA® (adalimumab) for the treatment of moderately active Crohn's disease (CD) in adult patients who have had an inadequate response to conventional therapy. HUMIRA has been approved for severely active CD in adults in the European Un more

• Immune system molecule weaves cobweb-like nanonets to snag Salmonella, other intestinal microbes

    A team of researchers led by UC Davis Health System has found that human alpha-defensin 6 (HD6) – a key component of the body's innate defense system – binds to microbial surfaces and forms "nanonets" that surround, entangle and disable microbes, preventing bacteria from attaching to or invading i more

Publications Crohn's Disease

• Crohn's Disease Loci Are Common Targets of Protozoa-Driven Selection

  Previous studies indicated that a few risk variants for autoimmune diseases are subject to pathogen-driven selection. Nonetheless, the proportion of risk loci that has been targeted by pathogens and the type of infectious agent(s) that exerted the strongest pressure remain to be evaluated. We asses more

• All SNPs Are Not Created Equal: Genome-Wide Association Studies Reveal a Consistent Pattern of Enrichment among Functionally Annotated SNPs

  by Andrew J. Schork, Wesley K. Thompson, Phillip Pham, Ali Torkamani, J. Cooper Roddey, Patrick F. Sullivan, John R. Kelsoe, Michael C. O'Donovan, Helena Furberg, The Tobacco and Genetics Consortium , The Bipolar Disorder Psychiatric Genomics Consortium , The Schizophrenia Psychiatric Genomics Cons more

• Role of SHIP1 in cancer and mucosal inflammation

  The SH‐2 containing inositol 5′‐polyphosphatase 1 (SHIP1) is a multifunctional protein expressed predominantly, but not exclusively, by hematopoietic cells. SHIP1 removes the 5′‐phosphate from the product of PI3K, PI(3,4,5)P3, to generate PI(3,4)P2. Both PIP species influence the activity level of more

Market studies Crohn's Disease

• Crohn's Disease – Pipeline Review, H2 2012

  Introduction Global Markets Direct’s, 'Crohn's Disease - Pipeline Review, H2 2012', provides an overview of the Crohn's Disease therapeutic pipeline. This report provides information on the therapeutic development for Crohn's Disease, complete with latest updates, and special features on late-stag more

• Crohn's Disease – Pipeline Review, H1 2012

  Introduction Global Markets Direct’s, 'Crohn's Disease - Pipeline Review, H1 2012', provides an overview of the Crohn's Disease therapeutic pipeline. This report provides information on the therapeutic development for Crohn's Disease, complete with latest updates, and special features on late-stag more

• Given Imaging Ltd. (GIVN) - Financial and Strategic SWOT Analysis Review

  Given Imaging Ltd. (GIVN) - Financial and Strategic SWOT Analysis Review Summary Given Imaging Ltd. (Given Imaging) is engaged in the development, manufacture and marketing of innovative diagnostic products used in the visualization and detection of gastrointestinal (GI) tract disorders. The compa more

Websites Crohn's Disease