Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications
Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diagnostics more
Cytokine Quantification in Drug Development
Immuno-PCR (IPCR) and ElectroChemiLuminescence (ECL) are technologies for improved performance of immunoassays. The specific advantages of the different technologies, using enzymatic or electrical signal amplification, allow for tailored assay design and address several specific challenges, ... more
High sensitive detection of follistatin by Imperacer®: an initial study on the way to analytical gene-doping tests
For the understanding of interactions in the muscle-growth directing myostatin-pathway and therefore also for the establishment of high sensitive detection strategies for gene-doping, detailed studies of protein concentration levels in biological matrices and appropriate highly sensitive an ... more