Combinatorial Chemistry

Products Combinatorial Chemistry

Focused Microwave Synthesis with CEM Systems

The Discover line of microwave synthesis systems is built upon CEM's Focused™ Microwave Technology designed to automatically focus microwave energy with maximum efficiency to the reaction more

Sterile plates enhance cellular growth applications

BactiGrowth plates from Porvair Sciences Ltd. offer a contamination free deep-well microplate optimised for high yield growth of bacteria, yeast and more

Liberty Microwave-Enhanced Peptide Synthesis

Microwave peptide synthesis is a well-accepted technology that has been cited in over 300 publications. Microwave energy offers benefits for both the coupling and deprotection reactions during peptide synthesis more

Videos Combinatorial Chemistry

Liberty Microwave-Enhanced Peptide Synthesis

Over the past several years, chemists have been using microwave energy to conduct a multitude of organic reactions with transformations taking place in a matter of minutes compared to hours with traditional methods. Now for the first time, microwave synthesis has been applied to the complete proces more

Focused Microwave Synthesis with CEM Systems

Single-mode cavity design At the heart of the new Discover System resides the technology which makes it so unique. The patented circular single-mode cavity design directs the microwave energy into a defined area, resulting in a homogenous field pattern surrounding the sample. "Focusing" the microwav more

News Combinatorial Chemistry

• Cost Benefits and Considerable Scientific Expertise Provide China Strategic Advantage for Drug Discovery Outsourcing

  With fast-paced advancements in genomics, combinatorial chemistry, and high-throughput screening, China has emerged as a major location to which drug discovery is being outsourced. China has the advantages of scientific expertise and comprehensive infrastructure, which are critical for drug discover more

• Currently positioned only 5th, China is the fastest growing biotech market in the world

  Novumed Life Science Consulting recently concluded an exclusive study on therapeutic biotech companies of the Asian Pacific region. China now positions as number 5 of most innovative biotech countries behind the US, the UK, Germany and Australia. In recent years, Chinese government incentives, low l more

• Synthetic biology yields clues to evolution and the origin of life

  Researchers in the field of synthetic biology are still a long way from being able to assemble living cells from scratch in the laboratory. But according to biochemist David Deamer of the University of California, Santa Cruz, their efforts are yielding clues to the mystery of how life began on Earth more

White papers Combinatorial Chemistry

• Alliances in Drug Discovery - The Chemical Element
  

  Alliances have evolved into a critical cornerstone of R&D strategy in the global pharmaceutical industry. No other industry has been leveraging this business model as successfully as the global pharmaceutical industry in its drive for innovation and success. Over three thousand deals amounting to a cumulative payout of US$ 17bn have been signed by pharmaceutical and biotech players in a span of two decades. In the past five years the industry's mania to develop new generation blockbuster drugs has taken on a new sense of urgency as 64% of the alliance value was inked and paid out during the period. more

Publications Combinatorial Chemistry

• Combinatorial synthesis of labelled drugs and PET tracers: synthesis of a focused library of 11C‐carbonyl‐labelled acrylamides as potential biomarkers of EGFR expression

  Combinatorial synthesis is extensively used in drug development and lead optimisation. However, this approach has rarely been used for positron emission tomography because of limitations in available technologies. [11C]Carbon monoxide is amenable to combinatorial synthesis in transition‐metal‐cata more

• A Combinatorial Library of Bi-functional Polymeric Vectors for siRNA Delivery In Vitro

  ABSTRACT Purpose To apply a combinatorial chemistry approach toward the design of polymeric vectors, and to evaluate their effectiveness as siRNA delivery systems in vitro. Methods Poly(acrylic acid) (pAA) was synthesized via RAFT polymerization with well-controlled molecular weights (M n: 3 kDa, 5 more

• From dynamic combinatorial ‘hit’ to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy

  The myotonic dystrophies (DM) are human diseases in which the accumulation of toxic RNA (CUG or CCUG) repeats in the cell causes sequestration of splicing factors, including MBNL1, leading to clinical symptoms such as muscle wasting and myotonia. We previously used Dynamic Combinatorial Chemistry t more

Market studies Combinatorial Chemistry

• Lifesciences IT - 2011 Yearbook

  GBI Research's research, “Lifesciences IT - 2011 Yearbook" provides key data, information and analysis on Lifesciences \IT that is being implemented by pharmaceutical companies. GBI Research expects that information technology (IT) in the lifesciences industry will become a trendsetter, helping phar more

Websites Combinatorial Chemistry