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Chimera Biotec is dedicated to the development of ultra-sensitive, customer-specific immunoassays for protein analysis based on their proprietary Imperacer® technology. Furthermore Chimera offers services and products for a broad range of applications. more
CANDOR - The ELISA Experts Stabilizers and Optimizers for Immunoassays CANDOR Bioscience GmbH offers buffer and solutions for optimising and stabilising immunoassays. For reliable results. • LowCross-Buffer® - Optimizer developed to minimise interference such as non-specific binding, cross react more
A new web page from Genevac brings together the latest technological innovations, applications advances and links to references that details how new more
Imperial Innovations Group plc announces that portfolio company Circassia has successfully completed a large-scale phase II clinical study of its ToleroMune® ragweed allergy treatment. Ragweed pollen is one of the main allergens responsible for hayfever in the US and its prevalence is increasing acr more
Apeiron Biologics AG announced that a clinical trial has started with the agent superoxide dismutase (project APN201) to investigate its potential for prevention of radiation dermatitis in breast cancer patients. Apeiron announced that a clinical trial has started with a liposomal topical formulati more
UCB announced the start of the EXXELERATE™ study which will evaluate the short- and long-term efficacy of Cimzia® (certolizumab pegol) plus methotrexate (MTX) compared with that of Humira®* (adalimumab) plus MTX in the treatment of moderate to severe rheumatoid arthritis (RA). The start of this stud more
Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diagnostics more
Immunoassays are bioanalytical methods based on antibodies. These include ELISA, EIA, RIA, Western blotting, protein arrays, lateral flow assays (immuno-chromatography), immunohistochemistry or immuno-PCR. Antibodies detect the substances (analytes) in immunoassays. This detection is always highly specific and only the analytes are detected and bound. This is the theory! Practically any antibody not only binds its analyte. It also binds several other substances, but with very different affinities. more
Sepsis is the most common cause of death in hospitalized patients worldwide. Inadequate antibiotic therapy represents an independent determinant of patients' mortality. Promptness of pathogen detection and the appliance of appropriate antibiotics are the cornerstones of management of severe bacterial infections. Furthermore, resistance to antibiotics is an increasing public health problem that can be attributed largely to their overuse. Thus, rapid diagnostic tests with both superior positive and negative predictive values over current techniques are sorely needed. more
Abstract Historically, much drug discovery and development in psychopharmacology tended to be empirical. However, over the last 20 years it has primarily been target oriented, with synthesis and selection of compounds designed to act at a specific neurochemical site. Such compounds are then exami more
Background and purpose: There are few clinical studies on the attempted treatments and outcomes in patients with Susac syndrome (SS) (retinocochleocerebral vasculopathy). Methods: A retrospective review was performed of all patients presenting with SS at the Mayo Clinic in Rochester, Minnesot more
Summary. Entecavir (ETV) and tenofovir disoproxil fumarate (TDF) are potent nucleos(t)ide analogues (NUCs) recommended as first‐line monotherapies for chronic hepatitis B. In Phase III trials, ETV and TDF demonstrated superior efficacy, and comparable safety compared with other NUCs. In long‐term more
Introduction GlobalData’s report, “American Academy of Orthopaedic Surgeons Annual Meeting 2012 - Review and Analysis” provides information and analysis on the clinical studies and products presented at the 2012 American Academy of Orthopaedic Surgeons (AAOS) annual meeting. This report is built more
Introduction GlobalData, the industry analysis specialist, has released its new report, “Type 2 Diabetes - Global Drug Forecasts and Treatment Analysis to 2020”. The report is an essential source of information and analysis on the global type 2 diabetes therapeutics market. The report provides comp more
Introduction GlobalData, the industry analysis specialist, has released its new report, “Ovarian Cancer Therapeutics - Global Drug Forecasts and Treatment Analysis 2020”. The report is an essential source of information and analysis on the global ovarian cancer therapeutics market. The report provi more
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