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CANDOR - The ELISA Experts Stabilizers and Optimizers for Immunoassays CANDOR Bioscience GmbH offers buffer and solutions for optimising and stabilising immunoassays. For reliable results. • LowCross-Buffer® - Optimizer developed to minimise interference such as non-specific binding, cross react more
The Sartorius Group is a leading international laboratory and process technology provider covering the segments of biotechnology and mechatronics. Founded in 1870, the Goettingen-based company currently employs more than 4,500 persons. The major areas of activity in its biotechnology segment focu more
ASCA elaborates reaction schemes for the synthesis of organic compounds in the field of medicinal chemistry in co-operation with the pharmaceutical and chemical industries. more
BioMonitoring is about innovative testing solutions, regulatory expertise, comprehensive service, and trust more
The Discover line of microwave synthesis systems is built upon CEM's Focused™ Microwave Technology designed to automatically focus microwave energy with maximum efficiency to the reaction more
Reliable results even with critical analytes and matrices. Avoid using additional HAMA blocker! more
More than 3500 highly purified secondary antibodies & conjugates for all immunological staining methods for specific signals and low background more
The Fisher Scientific Catalogue presents the top product range for your lab applications including 10,000 new products and 30 new brands more
SGE offers a comprehensive range of GC capillary columns for almost any chromatographic application providing the best possible combination of Performance more
Over the past several years, chemists have been using microwave energy to conduct a multitude of organic reactions with transformations taking place in a matter of minutes compared to hours with traditional methods. Now for the first time, microwave synthesis has been applied to the complete proces more
Single-mode cavity design At the heart of the new Discover System resides the technology which makes it so unique. The patented circular single-mode cavity design directs the microwave energy into a defined area, resulting in a homogenous field pattern surrounding the sample. "Focusing" the microwav more
The DNA double helix has been one of the most recognisable structures in science ever since it was first described by Watson and Crick almost 60 years ago (paper published in Nature in 25 April 1953). The binding and unbinding mechanism of DNA strands is vital to natural biological processes and to more
A year ago, the microtechnology, nanotechnology, and advanced materials industry looked out on the year 2012 with quite positive expectations. As it turned out, the unstable economic situation has left its mark on these industries, too. For 2013, at least, the companies expect a slight upwards trend more
The European Lead Factory, a novel platform for innovative drug discovery, was launched early February by an international consortium of 30 partners including the Lead Discovery Center GmbH (LDC). LDC is an expert in the discovery and generation of small molecule lead series by translating basic res more
The cortical collecting duct regulates ion and water homeostasis in the kidney. A cell line denoted M-1 has been established from the cortical collecting duct of a transgenic mouse that exhibits many functional properties of the original tissue. While this cell line is valuable for in vitro studies, the cells are not easily transfected. Frequently, adenovirus-mediated gene transfer is used. As adenovirus production requires several additional steps, we prefer chemical methods to achieve recombinant protein expression in M-1 cells. Previous attempts to transfect this cell line were unsuccessful with far less than 10% of transfectants, although different reagents were tried. Here we compare three commercially available transfection reagents in terms of the percentage of transfected cells and the suitability for using a reporter construct in M-1 cells. more
The detection of SNPs (single nucleotide polymorphisms) is an important tool for researchers in order to find mutations in DNA sequences. In this application note we describe a homogeneous fluorescence assay based on PCR. The Amplifluor® SNPs HT Genotyping System from Millipore was used to screen a number of samples with the help of the FLUOstar OPTIMA multidetection microplate reader from BMG LABTECH more
Transfection is the delivery of DNA, RNA, proteins, and macromelecules into eukaryotic cells. The goals for transfection include the study of gene function and regulation as well as protein expression and function. It is also used for gene silencing and protein production. According to the application, the information can be either transiently (transient transfection) or permanently expressed (stable transfection). Based on the strategies, the transfection methods can be divided into three groups: more
Day 1: This introductory course consists of a theoretical part and a practical part where participants get to do qPCR experiments by themselves under experienced supervision. The course contains: Basic PCR theory The theory of real-time PCR Applications and possibilities of qPCR. Comparison of qPC more
This is a 1-day course in multiplex PCR with a focus on multiplex real-time PCR. The course consists of a theoretical part and a practical part where participants get to do multiplex qPCR experiments by themselves under experienced supervision. The course contains: Introduction to multiplex PCR Mu more
This is an introductory course to miRNA analysis using qPCR. The course consists of a theoretical part and a practical part where participants get to do miRNA experiments by themselves under experienced supervision. The course covers: Introduction to miRNA Applications, what can miRNA analysis be more
GC-biased gene conversion (gBGC) is a process associated with recombination that favors the transmission of GC alleles over AT alleles during meiosis. gBGC plays a major role in genome evolution in many eukaryotes. However, the molecular mechanisms of gBGC are still unknown. Different steps of the more
Analysis of genetic differences (gene presence/absence and nucleotide polymorphisms) among strains of a bacterial species is crucial to understanding molecular mechanisms of bacterial pathogenesis and selecting targets for novel antibacterial therapeutics. However, lack of genome-wide association s more
Due to structural flexibility, RNase sensitivity, and serum instability, RNA nanoparticles with concrete shapes for in vivo application remain challenging to construct. Here we report the construction of 14 RNA nanoparticles with solid shapes for targeting cancers specifically. These RNA nanopartic more
Miraculins Inc (Miraculins) is a research and development company engaged in the discovery and validation of cancer biomarkers, which enable the development of diagnostic tools and therapeutic products. The company focuses on biomarker discovery using its proprietary B.E.S.T Platform for the screeni more
Chemizon, Inc. (Chemizon) is a biotechnology company, engaged in the discovery and development of innovative therapeutics. The company owns an integrated drug discovery platform based on medical chemistry, biology, computational chemistry, ADME/DMPK and pharmacology to accelerate drug development pr more
The in vitro diagnostics market in India has gathered momentum in the last few years. Several companies, both domestic as well as foreign are entering the business with enthusiasm due to the tremendous growth the industry has been experiencing. The steadily growing number of medical centers in the c more
AKos Consulting & Solutions GmbH Home Company Info Impressum Contact Email a chemoinformatics company What is new: Use CWM Global Search Use ACD (Available Chemicals Directory) free of charge Isentris Personal - an extremely powerful and low-cost chemical information system - get a 30 day free ev more
Contact Us Business Development Future Products Lead Product Target Pre-clinical Summary Clinical Studies Technology Team Management Team Board of Directors Scientific Advisors Home News & Events Leadership in Respiratory Disease Therapy Altair Therapeutics, Inc. is a biopharmaceutical company devel more
Learn how Aureus Pharma streamlines critical research functions… EVENT SCHEDULE ISSX Meeting September 4-8, 2010 XXIst ISMC September 5-9, 2010 Drug Drug Interactions Webinar September 21, 2010 See all events REQUEST WEB DEMO Examine Aureus Pharma’s Knowledge Management System from your more
Antagonism chemistry In chemistry , antagonism is a phenomenon where two or more agents in combination have an overall effect which is less than the sum of their individual effects. The word is most commonly used in this context in biochemist ... more
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