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RNAiONE - Identification of optimal shRNA sequences for knockdown cell systems, for target validation and for screening applications more
The BioPAT® analysis system is used for simultaneous online monitoring of the two analytes, glucose and lactate in laboratory or industrial cultivations more
Faster and more efficient generating of clones – world’s fastet, validated system for automated isolation of mammalian clones form semi-solid media, fully automated on the MICROLAB® STAR Line more
BRAIN AG discloses a breakthrough in human cellbased assay technology to identify and develop novel taste modulators and nutraceuticals. For the first time, researchers at BRAIN succeeded in establishing immortalized primary human taste cell lines derived from taste papillae of the human tongue. Hum more
Immutep and Lonza announced an agreement for cell line selection, master cell banking and process development of ImmuFact(R) IMP321. Lonza will initiate the process development for Immutep’s lead product, using Immutep's newly-developed proprietary cell lines. Immutep announced Phase I/II results fo more
Molecular Imaging, Inc., a specialty contract research organization providing multi-modality preclinical in vivo imaging services to pharmaceutical and biotechnology companies, announced that it has entered into a licensing agreement with Dana-Farber Cancer Institute to access a substantial number o more
The Nobel Assembly awarded this year's Nobel Prize in Medicine to Elizabeth H. Blackburn, Jack W. Szostak, and Carol W. Greider for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase. With their ingenious genetic research and meticulous biochemical studies, they not only solved a fundamental problem in biology but also opened a new field of research and initiated the development of potential therapies against disease more
The novel small molecule inhibitors are often substrates of ABC transporters which influence the pharmacokinetic parameters of the drug candidates and cause drug resistance of tumor cells. Therefore expression profiling of ABC transporter genes in cell lines used for drug screening is highly important for anti-cancer drug discovery projects. Our purpose was to create a basic expression profile of ABC transporters in our mainly used lung cancer cell lines using the RealTime ready ABC Transporter Panel.The RealTime ready ABC-Transporter Panel comprises the 42 most important human ABC transporters in duplicate. The panel includes five controls for RNA quality and seven reference gene assays. The assays are supplied in a LightCycler® Instrument 480 Multiwell Plate 96 and contain target specific primers and a FAM-labeled Universal ProbLibrary hydrolysis probe that contains LNA more
RealTime ready qPCR Assays redefine real-time qPCR because each assay is function-tested in PCR and qualified under strict criteria to assure superior performance. The RealTime ready Assays are based on the well-known Universal ProbeLibrary (UPL) technology and are available in a ready-to-use formulation as dried-down assays in LightCycler® 480 Multiwell Plates 96 and 384, or as a primer probe mix for single assays in a liquid formulation for all real-time PCR platforms available in the market more
Abstract Integration of genome‐wide profiles of DNA copy number alterations (CNAs) and gene expression variations (GEVs) could provide combined power to the identification of driver genes and gene networks in tumors. Here we merge matched genome and transcriptome microarray analyses from neurobla more
Abstract Sortase‐mediated protein ligation is a biological covalent conjugation system developed from the enzymatic cell wall display mechanism found in Staphylococcus aureus. This three‐component system requires: (i) purified Sortase A (SrtA) enzyme; (ii) a substrate containing the LPXTG peptide more
Abstract Cellular fates such as proliferation, differentiation, and death are controlled by a variety of cytokine receptors, which are crucial in initiating downstream signaling cascades. To initiate signaling, the cytokine receptor cytoplasmic domain recruits specific signaling molecules with a more
Stemgent, Inc. - Strategic SWOT Analysis Review Summary Stemgent, Inc. (Stemgent) is a stem cell research company which works in sync with the world’s leading stem cell scientist to develop stem cell-qualified reagents including the small molecules, media, and tools for the generation of iPS cells more
Cellectis S.A. (Cellectis) is a biotechnology company, engaged in the development of high-precision, high-performance systems for DNA surgery and cell reprogramming. The company has two subsidiaries, namely, Cellectis Genome Surgery and Cellectis Bioresearch. The products of the company includes cGP more
Geneart AG (Geneart) is a publicly held service provider that is engaged in providing solutions for DNA engineering and processing in the field of improved medicine and biotechnology. The company's services include gene synthesis, gene evolution services, plasmid services, GMP plasmid manufacturing, more
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List of contaminated cell lines This is a list of cell culture s which have been cross-contaminated and overgrown by other cells. A project is currently underway to enumerate and rename contaminated cell lines to avoid errors in research caused ... more
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