Cell Based Assays

Companies Cell Based Assays

CCS Cell Culture Service GmbH, Germany

CCS generates stably transfected cell lines for cell based drug screening and produces recombinant proteins from mammalian and insect cells. more

CCS Cell Culture Service, Inc., USA

We Make The Cells! The use of cell based assays for drug screening brings about the challenge of in-time cell production and scale-up. As a flexible external cell culture unit CCS supplies starting material for advanced screening and makes screening faster and more efficient. Within few years CCS ha more

News Cell Based Assays

• Sigma Life Science Announces Scientific Advisory Board to drive ADME/Tox program

  Sigma Life Science, the biological products and services research business of Sigma-Aldrich Corporation, announced the formation of an ADME/Toxicology Scientific Advisory Board (ADME/Tox SAB) in an effort to help drive development of new cell-based assays using the Company's innovative CompoZr ZFN t more

• Chris Beaver joins Pharmanet as Director, Immunochemistry Services

  PharmaNet Development Group, Inc. announced that Chris Beaver, PhD has joined the Company as Director, Immunochemistry Services. Dr. Beaver is responsible for leading the immunochemistry team within the Company’s bioanalytical laboratories and expanding its large molecule services, including assay more

• Microfluidic device allows collection, analysis of hard-to-handle immune cells

  A team led by Massachusetts General Hospital (MGH) scientists has developed a new microfluidic tool for quickly and accurately isolating neutrophils – the most abundant type of white blood cell – from small blood samples, an accomplishment that could provide information essential to better understan more

White papers Cell Based Assays

• alamarBlue® Assay for Assessment of Cell Proliferation using the FLUOstar OPTIMA
  

  The alamarBlue® cell proliferation assay is based on a reducing environment that indicates metabolic active cells. Active cells are able to convert resazurin into the resorufin. Resazurin is blue and non-fluorescent whereas resorufin is red and highly fluorescent; therefore a fluorescent and a colorimetric detection are possible. This application notes focuses on the quantification of cell proliferation in a Human Osteoblast cell culture by measuring alamarBlue® fluorescence on the FLUOstar OPTIMA microplate reader more

• Label-Free and Dynamic Monitoring of Cell-Based Assays
  

  The xCELLigence system from Roche Applied Science, originally invented by the US company ACEA Biosciences, allows for label-free and dynamic monitoring of cell-based assays. The xCELLigence system utilizes impedance readout to non-invasively quantify cellular status in real-time [1]. The cells are seeded in 96-well microtiter E-Plates with integrated microelectronic sensor arrays at the bottom of each well. more

Publications Cell Based Assays

• Discovery of a new bioactive molecule for neuroblastoma

  Abstract Neuroblastoma, a common pediatric malignancy of neural crest origin, is unique in its wide spectrum of clinical and biological behavior, ranging from spontaneous regression or differentiation to rapid progression and metastasis. Overexpression of neurotrophin receptors of the tyrosine k more

• Controllable Hydrogen Sulfide Donors and Their Activity against Myocardial Ischemia-Reperfusion Injury

  Hydrogen sulfide (H2S), known as an important cellular signaling molecule, plays critical roles in many physiological and/or pathological processes. Modulation of H2S levels could have tremendous therapeutic value. However, the study on H2S has been hindered due to the lack of controllable H2S relea more

• A RANKL-PKC{beta}-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts [Research Papers]

  Bone resorption by osteoclasts requires a large number of lysosomes that release proteases in the resorption lacuna. Whether lysosomal biogenesis is a consequence of the action of transcriptional regulators of osteoclast differentiation or is under the control of a different and specific transcript more

Market studies Cell Based Assays

• Asterand plc (ATD) - Financial and Strategic SWOT Analysis Review

  Asterand plc. (Asterand) is a biotechnology company that is engaged in providing human tissue based research services to drug discovery and development pharmaceutical, biotechnology. The company operates through its subsidiaries including wholly owned, namely, Asterand UK Limited and Asterand, Inc. more

• Pharmaceuticals Bundle

  Anti-Infective Drugs Markets Six infectious diseases--pneumonia, tuberculosis, diarrheal diseases, malaria, measles and HIV/AIDS--account for half of all premature deaths worldwide, killing mostly children and young adults, according to the World Health Organization (WHO). Moreover, threatening pan more

Websites Cell Based Assays