Biosafety

Products Biosafety

Safe Vacuum Aspiration of Liquids in Biosafety Level 1, 2 & 3 Laboratories

VACUSAFE is designed to provide simple, reliable and safe aspiration of hazardous waste liquids in Microbiological and Biomedical Laboratories. more

News Biosafety

• Trenzyme receives approval for biosafety level 2 (BSL-2)

  The Konstanz (Germany)-based Trenzyme GmbH just received approval for their biosafety level 2 (BSL-2) facility. Trenzyme is a biotech company offering a wide range of services in research and development for their customers. The company's core strengths are their cell line development as well as pro more

• Novel 'antisense' therapies protect primates from lethal Ebola and Marburg viruses

  New studies show that treatments targeting specific viral genes protected monkeys infected with deadly Ebola or Marburg viruses. Furthermore, the animals were protected even when therapeutics were administered one hour after exposure — suggesting the approach holds promise for treating accidental in more

• Responsible science for do-it-yourself biologists

  Remember chemistry sets, ham radio, amateur astronomy, and early computing? Well, now it is biology's turn. Today, over 2,000 people from around the world belong to the Do-It-Yourself Biology (DIYbio) community, working on everything from microbial fuel cells, low-cost lab equipment, environmental s more

White papers Biosafety

• Transfecting Mouse Fibroblast NIH 3T3 Cells with Lipid Reagents - A Comparative Study
  

  Prior to the advent of transfection lipids, mouse fibroblast NIH 3T3 cells were essentially untransfectable and other methods such as retroviral gene delivery had to be employed to circumvent this problem. Although retroviruses can be used for transgene expression in 100% of cells, the expression is often low. Additionally, NIH 3T3 cells are traditionally used for cellular transformation studies, and creating oncogenic retroviruses is not ideal due to bio-safety concerns. Recently, lentivruses have been used for high gene expression in cells (up to 100%). However, this method causes even greater bio-safety concerns and requires updating culture facilities to bio-safety level 2+, resulting in a costly and time-consuming procedure. more

• Optimized Production of Lentivirus Using FuGENE® HD Transfection Reagent
  

  Lentiviral vectors are ideally suited vehicles for a broad range of research applications. Depending on pseudotype, lentiviruses infect a wide range of cell types, non-discriminately transducing both dividing and non-dividing cells. As opposed to other popular vector delivery systems, lentivirus stably and rapidly integrates genetic payload into the host genome allowing for long-term studies in vivo. Current lentiviral vector systems can accommodate upwards of ten kilobases of foreign DNA [1], although promoter and enhancer elements reduce the practical size of gene open-reading frames to perhaps five or six kilo­bases, which is sufficient to accommodate most genes commonly studied in the mammalian genome. more

Publications Biosafety

• Thermoresponsive Bacterial Cellulose Whisker/Poly(NIPAM-co-BMA) Nanogel Complexes: Synthesis, Characterization, and Biological Evaluation

  Dispersions of poly(N-isopropylacrylamide-co-butyl methacrylate) (PNB) nanogels are known to exhibit reversible thermosensitive sol–gel phase behavior and can consequently be used in a wide range of biomedical applications. However, some dissatisfactory mechanical properties of PNB nanogels can limi more

• Biosafety Data as Confidential Business Information

  by Kaare M. Nielsen more

• A self‐deletion lentiviral vector to reduce the risk of replication‐competent virus formation

  Abstract Background Major improvements have been made progressively on human immunodeficiency virus (HIV)‐1 based lentiviral vectors to minimize the probability of replication‐competent lentivirus formation. This includes the deletion of U3 promoter and the use of packaging cells, which has in more

Market studies Biosafety

• RNL BIO Co., Ltd. (003190) - Financial and Strategic SWOT Analysis Review

  RNL BIO Co., Ltd. (RNL BIO) is a publically held biotechnology company. The company is principally engaged in the development and manufacture of stem cell therapy products. RNL BIO offers products in two categories endocrine remedies which includes anti diabetes mellitus, growth promotion and diet p more

Websites Biosafety