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Topic biomarkers

Companies biomarkers

Chimera Biotec GmbH, Germany

Chimera Biotec is dedicated to the development of ultra-sensitive, customer-specific immunoassays for protein analysis based on their proprietary Imperacer® technology. Furthermore Chimera offers services and products for a broad range of applications. more

CANDOR Bioscience GmbH, Germany

CANDOR - The ELISA Experts Stabilizers and Optimizers for Immunoassays CANDOR Bioscience GmbH offers buffer and solutions for optimising and stabilising immunoassays. For reliable results. • LowCross-Buffer® - Optimizer developed to minimise interference such as non-specific binding, cross react more

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White papers biomarkers

  • Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications

    Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diagnostics more

  • Cytokine Quantification in Drug Development

    Immuno-PCR (IPCR) and ElectroChemiLuminescence (ECL) are technologies for improved performance of immunoassays. The specific advantages of the different technologies, using enzymatic or electrical signal amplification, allow for tailored assay design and address several specific challenges, such as maximum sensitivity up to 1 fg/ml target cytokine, simultaneous detection of multiple antigens, and high robustness against biological matrices more

  • Eternal shelf-life for ELISA?

    Reliable long-term stabilization of immunoassay components is beneficial in many applications. Stabilization and storage of components are important for effective workflows not only for performing large numbers of ELISA but also for medium and small numbers of ELISA. This article deals with the state of the art - particularly with regard to food, veterinary or clinical diagnostics. Clinical immuno diagnostics require adequate stabilization of assay components according to EU guidance (IVDD 98/79/EC) or corresponding international regulations before launch. more

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