Biomarkers

Companies Biomarkers

CANDOR Bioscience GmbH, Germany

CANDOR - The ELISA Experts Stabilizers and Optimizers for Immunoassays CANDOR Bioscience GmbH offers buffer and solutions for optimising and stabilising immunoassays. For reliable results. • LowCross-Buffer® - Optimizer developed to minimise interference such as non-specific binding, cross react more

News Biomarkers

• Exhaled diagnosis – what your breath can reveal about your health

  Analytical chemists have measured the levels of selected organic compounds found in human breath, with the aim of one day applying the technique to the routine diagnosis of disease. The analysis of biomarkers in exhaled air and in blood can reveal the presence of cancer, the rejection of organs from more

• Bedside detection of the signatures of heart disease

  A disposable point-of-care device has been designed that can detect cardiac troponin I (cTnI) – a biomarker that is highly specific to cardiac injury. The approach uses a surface acoustic wave immunosensor packaged within a disposable microfluidic cartridge that can test for cTnI in the blood. The n more

• New hope in fight against multi-resistant germs

  An increasing number of bacteria is evolving antibiotic resistance. Much-feared representatives of this steadily growing group include Staphylococci strains. At this point, multi-resistant forms of the bacterium Staphylococcus aureus - the "hospital germ" known commonly by its acronym, MRSA - can on more

White papers Biomarkers

• Cytokine Quantification in Drug Development
  

  Immuno-PCR (IPCR) and ElectroChemiLuminescence (ECL) are technologies for improved performance of immunoassays. The specific advantages of the different technologies, using enzymatic or electrical signal amplification, allow for tailored assay design and address several specific challenges, such as maximum sensitivity up to 1 fg/ml target cytokine, simultaneous detection of multiple antigens, and high robustness against biological matrices more

• Eternal shelf-life for ELISA?
  

  Reliable long-term stabilization of immunoassay components is beneficial in many applications. Stabilization and storage of components are important for effective workflows not only for performing large numbers of ELISA but also for medium and small numbers of ELISA. This article deals with the state of the art - particularly with regard to food, veterinary or clinical diagnostics. Clinical immuno diagnostics require adequate stabilization of assay components according to EU guidance (IVDD 98/79/EC) or corresponding international regulations before launch. more

• High sensitive detection of follistatin by Imperacer®: an initial study on the way to analytical gene-doping tests
  

  For the understanding of interactions in the muscle-growth directing myostatin-pathway and therefore also for the establishment of high sensitive detection strategies for gene-doping, detailed studies of protein concentration levels in biological matrices and appropriate highly sensitive analytic techniques for quantitative monitoring of these biomarkers are required. In this work, the development of a high sensitive assay for follistatin based on the Imperacer® technology is described. The quantification limit in human serum was found at 60 pg/ml in only 6 µl sample volume. With this initial assay we demonstrate the first application in a set of analytical tests for a high sensitive myostatin pathway related profiling. more

Publications Biomarkers

• NanoPad: an integrated platform for bacterial production of camel nanobodies aimed at detecting environmental biomarkers

  The presence of given antigens in environmental samples (e.g. biodegradative enzymes) report the quality and catalytic vigor of particular soils or aquatic ecosystems. In this context, we have developed the NanoPad system, consisting of a complete platform for isolation, amplification and extracel more

• Volatile Metabolites of Pathogens: A Systematic Review

  by Lieuwe D. J. Bos, Peter J. Sterk, Marcus J. Schultz Ideally, invading bacteria are detected as early as possible in critically ill patients: the strain of morbific pathogens is identified rapidly, and antimicrobial sensitivity is known well before the start of new antimicrobial therapy. Bacter more

• Gender‐specific transcriptomic response to environmental exposure in flemish adults

  Flanders, Belgium, is one of the most densely populated areas in Europe. The Flemish Environment and Health Survey (2002–2006) aimed at determining exposure to pollutants of neonates, adolescents, and older adults and to assess associated biological and health effects. This study investigated geno more

Market studies Biomarkers

• Endpoints - Clinical Trials in Respiratory Diseases - Pulmonary Function Tests, Biomarkers and Quality of Life Questionnaires All Play Prominent Roles

  GBI Research in its report “Endpoints - Clinical Trials in Respiratory Diseases - Pulmonary Function Tests, Biomarkers and Quality of Life Questionnaires All Play Prominent Roles” presents the use of endpoints or outcomes measures in respiratory disease’s clinical trials. In this report, endpoint us more

• Endpoints - Clinical Trials in Cardiovascular Disorders - Optimal Use of Surrogate Endpoints and Clinical Biomarkers are Key Determinants of Success

  GBI Research, the leading business intelligence provider, has released its latest research “Endpoints - Clinical Trials in Cardiovascular Disorders - Optimal Use of Surrogate Endpoints and Clinical Biomarkers are Key Determinants of Success” which provides an insight into the different endpoints tha more

• Global Flow Cytometry Market

  Flow cytometry is a laboratory analytical technique that can rapidly measure multiple parameters of individual cells or particles as they pass through a beam of light, typically a laser. The global flow cytometry market remains one of the fastest-growing segments of life sciences and clinical diagno more

Websites Biomarkers