Biochemistry

News Biochemistry

• New bio-adhesive polymer demonstrated

  An article in JoVE, Journal of Visualized Experiments, details the use of a new laser-activated bio-adhesive polymer. The chitosan-based polymer, SurgiLux, was developed by scientists at the University of New South Wales. Chitosan is a polymer derived from chitin, which is found in fungal cell walls more

• Chemists develop reversible method of tagging proteins

  Chemists at UC San Diego have developed a method that for the first time provides scientists the ability to attach chemical probes onto proteins and subsequently remove them in a repeatable cycle.Their achievement, detailed in a paper that appears in Nature Methods, will allow researchers to better more

• Good timing: NIST/CU collaboration adds timing capability to living cell sensors
  

  Individual cells modified to act as sensors using fluorescence are already useful tools in biochemistry, but now they can add good timing to their resumé, thanks in part to expertise from the National Institute of Standards and Technology (NIST).With the added capability to track the timing of dynam more

White papers Biochemistry

• From Sephadex to GE Healthcare
  

  The success of chromatography as a technique for separating biomolecules is inevitably linked to the introduction of the gel filtration medium Sephadex(TM) by Pharmacia AB in 1959 more

• Increased Vitality of Primary Mouse Hepatocytes Isolated with Liberase TM Research Grade
  

  As drugs applied to organisms are metabolized via the liver, hepatocytes represent a useful and common study model. Primary hepatocytes are widely used to evaluate the toxic effects of drugs and xenobiotics. A variety of metabolic parameters have been described to analyze the functionality of hepatocytes. Via those parameters, the toxic effect of substances can easily be quantified. One drawback of primary hepatocyte culture is the short duration of survival and the high sensibility of the cells. Therefore, every step towards a more gentle method of isolating the cells increases cell number and vitality and thus improves the outcome of biomedical research applications more

• Membrane Fluidity Measurements Using UV Fluorescence Polarization and the POLARstar Omega
  

  The POLARstar Omega microplate reader from BMG LABTECH was used to study membrane fluidity via fluorescence polarization in 96-well format. The method allows for the monitoring of large scale alterations in membrane fluidity (such as phase transitions), as well as more subtle changes in lipid dynamic. The change in polarization caused by dibucaine and propranolol were investigated in both liposomes and mitochondrial membranes more

Events Biochemistry

• Cell Normalization Using Adhesive Micropatterns

  Content & Learning Objective The most common cell culture method to study cell behavior under different stimuli, is the Petri Dish or its variants in multi-well plates. These systems are easy to use and versatile but still suffer from large cell variability. Reducing cell variability and developing more

• 1 day Sample preparation and quality control of nucleic acids

  One of the most important requirements to get good results from qPCR experiments is to have a template of good quality. In most cases this means having an efficient sample preparation. This course module is focused on extraction of RNA and DNA to be used as template in qPCR and reverse transcription more

• 2 days Experimental design and statistical data analysis for qPCR

  The two-days course covers the most of the same prinicples as the three-day analysis course but less comprehensive and with less practical excercises Day 1- Statistical analysis of real-time PCR data Basic principles of statistics Advanced principles of statistics Statistical tests Ability to det more

Publications Biochemistry

• Tryptophan-mediated charge-resonance stabilization in the bis-Fe(IV) redox state of MauG [Biochemistry]

  The diheme enzyme MauG catalyzes posttranslational modifications of a methylamine dehydrogenase precursor protein to generate a tryptophan tryptophylquinone cofactor. The MauG-catalyzed reaction proceeds via a bis-Fe(IV) intermediate in which one heme is present as Fe(IV)=O and the other as Fe(IV) w more

• [Perspective] Biochemistry: Structural MS Pulls Its Weight

  Mass spectrometry provides insights into the structure and dynamics of ever-larger protein assemblies and associated biomolecules. more

• A paucity of liver disease in Canadian Inuit with chronic hepatitis B virus, subgenotype B6 infection

  Summary Clinical observations suggest that chronic hepatitis B virus (HBV) infections in the Canadian Inuit are less often associated with serious adverse outcomes than has been described in other HBV‐infected patient populations. The aim of this study was to document the clinical and biochemica more

Market studies Biochemistry

• In Vitro Diagnostics Market in India 2012

  The in vitro diagnostics market in India has gathered momentum in the last few years. Several companies, both domestic as well as foreign are entering the business with enthusiasm due to the tremendous growth the industry has been experiencing. The steadily growing number of medical centers in the c more

• Taiwan Pharmaceuticals and Healthcare Report Q4 2012

  BMI View: Having been calculated to have reached TWD135.10bn (US$4.59bn) in 2011 sales, Taiwan’s pharmaceutical market is expected to post a compound annual growth rate (CAGR) of 3.3% in local currency terms to 2016, which is considerably below the historical (2006-2011) – and already modest - growt more

• Mediwatch Plc (MDW) - Financial and Strategic SWOT Analysis Review

  Mediwatch Plc (MDW) - Financial and Strategic SWOT Analysis Review Summary Mediwatch Plc (Mediwatch) is a medical device company engaged in the development and manufacture of care products used in the diagnosis of urological disorders and early detection of prostate cancer. The products developed more

Websites Biochemistry