Topic basic research

News basic research

• Molecular simulations confirm role of functional rotation in multidrug resistance

  A new molecular simulation technique developed by researchers at RIKEN and Kyoto University has confirmed for the first time the function of the transporter protein AcrB in E. coli multidrug resistance. The result marks a key step in efforts to combat antibiotic resistance, demonstrating the power o more

• Cooperation in diabetes research

  The Max Planck Institute (MPI) of Biochemistry in Martinsried and pharmaceutical company GlaxoSmithKline GmbH & Co. KG (GSK) have signed a research agreement on the development of new drugs for the treatment of type II diabetes. The cooperation agreement, negotiated with the help of technology trans more

• MDxHealth Outlines New Strategy

  MDxHealth, formerly known as OncoMethylome Sciences, announced further details regarding its revised business strategy. For the past several months, MDxHealth’s management has worked very closely with the Board of Directors to define a strategic path to accelerate growth and monetization of the Comp more

White papers basic research

• Outsourcing R&D Innovation takes on New Meaning
  

  Innovative drugs are the lifeblood of pharmaceutical companies, but the cost of developing them is rising to unsustainable levels. Pharma executives are already saying that as the economy falters, they foresee bleak prospects and mergers unless their companies get more innovative drugs into their pipelines. The clock is ticking on the race to increase productivity, as key patents worth a projected $30 billion in revenue will expire between 2010 and 2013, opening the floodgates to competition from generics, according to Barbara Ryan, an analyst at Deutsche Bank. This imperative is propelling increased outsourcing of R&D operations as companies trim overcapacity. more

• Eternal shelf-life for ELISA?
  

  Reliable long-term stabilization of immunoassay components is beneficial in many applications. Stabilization and storage of components are important for effective workflows not only for performing large numbers of ELISA but also for medium and small numbers of ELISA. This article deals with the state of the art - particularly with regard to food, veterinary or clinical diagnostics. Clinical immuno diagnostics require adequate stabilization of assay components according to EU guidance (IVDD 98/79/EC) or corresponding international regulations before launch. more

• Improved Performance of the LightCycler®
  

  Real-time reverse transcription-PCR (RT-PCR) is con­sidered the method of choice for any experiments requiring­ sensitive, specific, and reproducible quantification of mRNA molecules of interest. It is an essential tool for basic research, molecular medicine, and biotechnology. more

Publications basic research

• A New Way of Identifying Biomarkers in Biomedical Basic-Research Studies

  by Alexander Yassouridis, Tonia Ludwig, Axel Steiger, Friedrich Leisch A simple, nonparametric and distribution free method was developed for quick identification of the most meaningful biomarkers among a number of candidates in complex biological phenomena, especially in relatively small more

• Enterprising science

  Enterprising science Nature 485, 7397 (2012). doi:10.1038/nj7397-269a Author: Peter Fiske Graduate students and postdocs are often best placed to turn basic research into entrepreneurial gold, argues Peter Fiske. more

• Small Molecules Present Large Opportunities in Plant Biology

  Since the introduction of chemical genomics to plant biology as a tool for basic research, the field has advanced significantly. There are now examples of important basic discoveries that demonstrate the power and untapped potential of this approach. Given the combination of protein and small-molecu more

Market studies basic research

• Medical & Biological Laboratories Co., Ltd. - Strategic SWOT Analysis Review

  Medical & Biological Laboratories Co., Ltd.(MBL) is engaged in the research, development and manufacture of clinical reagents and basic research reagents. It products are marketed to hospitals, research institutions and clinical testing centers. Its subsidiaries include MBL International (MBLI) and more

• Medical & Biological Laboratories Co., Ltd. (4557) - Strategic SWOT Analysis Review

  Medical & Biological Laboratories Co., Ltd.(MBL) is engaged in the research, development and manufacture of clinical reagents and basic research reagents. It products are marketed to hospitals, research institutions and clinical testing centers. Its subsidiaries include MBL International (MBLI) and more

• Becton, Dickinson and Company (BDX) - Product Pipeline Analysis

  Becton, Dickinson and Company (BDX) - Product Pipeline Analysis Summary Becton, Dickinson and Company (BD) is a medical technology company, serving large healthcare institutions, life science researchers and clinical laboratories. The company manufactures and sells medical devices, reagents and in more

Websites basic research