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Coronary computed tomography angiography (CCTA) is an effective tool for determining the risk of heart attacks and other adverse cardiac events in patients with suspected coronary artery disease but no treatable risk factors, such as high cholesterol or high blood pressure, according to a new study more
Most people probably know that heart disease remains the nation's No. 1 killer. But what many may be surprised to learn is that cholesterol has a major accomplice in causing dangerous arterial plaque buildup that can trigger a heart attack. The culprit? Inflammatory cells produced by the immune syst more
A Cambridge University research team has for the first time discovered a method of generating different types of vascular smooth muscle cells (SMCs) - the cells which make up the walls of blood vessels - using cells from patients' skin. This work could lead to new treatments and better screening for more
Platelet aggregation is a “gold standard” assay of platelet function in the research and clinical laboratory settings which is conventionally measured with aggregometers requiring large volumes of platelet suspensions and only in low throughput format. With the NOVOstar microplate reader from BMG LABTECH we present an alternative optical method to measure platelet aggregation using small volumes in 96-well format more
Atherosclerosis is a major risk factor for cardiovascular disease (CVD) and stroke. Galectin-3 is a carbohydrate-binding lectin implicated in the pathophysiology of CVD and is highly expressed within atherosclerotic lesions in mice and humans. The object of this present study was to use genetic del more
Chronic periodontitis (CP) is a common oral disease that confers substantial systemic inflammatory and microbial burden and is a major cause of tooth loss. Here, we present the results of a genome-wide association study of CP that was carried out in a cohort of 4504 European Americans (EA) particip more
Purpose Apolipoprotein E knockout (apoE−/−) mouse is one of the most popular models for cardiovascular research, especially in the study of atherosclerosis. Naturally, large amount of studies try to uncover the role of apoE in atherosclerosis, and indeed apoE plays an important role in this path more
Introduction Global Markets Direct’s, 'Atherosclerosis - Pipeline Review, H1 2012', provides an overview of the Atherosclerosis therapeutic pipeline. This report provides information on the therapeutic development for Atherosclerosis, complete with latest updates, and special features on late-stag more
GBI Research, the leading business intelligence provider, has released its latest research “Endpoints - Clinical Trials in Cardiovascular Disorders - Optimal Use of Surrogate Endpoints and Clinical Biomarkers are Key Determinants of Success” which provides an insight into the different endpoints tha more
Introduction Global Markets Direct’s, 'Atherosclerosis - Pipeline Review, H2 2012', provides an overview of the Atherosclerosis therapeutic pipeline. This report provides information on the therapeutic development for Atherosclerosis, complete with latest updates, and special features on late-stag more
Sitemap In English / På Svenska - Contact - At BioInvent, our goal is to use our expertise in antibody drug development to provide innovative antibody therapies for patients with unmet serious or life-threatening diseases. Home About BioInvent Products Partners Science Investors Media Centre Strateg more
Inflammation is a defense mechanism of the body to protect it from infection and injury. The inflammatory response is started by white blood cells releasing defense molecules to remove injurious stimuli such as damaged cells, pathogens or irritants. Redness, pain, swelling, heat and loss of more
Atherosclerosis Atherosclerosis is a disease affecting arterial blood vessel s. It is a chronic inflammatory response in the walls of arteries, in large part due to the deposition of lipoproteins (plasma proteins that carry cholesterol and tr ... more
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