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Find antibodies by searching for a name or antigen and narrow down your results by defining parameters like reactivity, application, conjugate etc.
- Flow Cytometry (FC)
- Fluorescence Microscopy
- Frozen Tissue Sections
- Functional Assays (FN)
- IHC Paraffin And Frozen
- Immunochemistry (IC)
- Immunocytochemistry (ICC)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Immunohistochemistry, frozen sections (IH ...
- Immunohistochemistry, paraffin-embedded s ...
- Immunoprecipitation (IP)
- Intracytoplasmic Staining
- Paraffin-embededded Tissue Sections
Cholesterol-lowering drug kills melanoma cells - If messenger substance is present
Special cholesterol-lowering drugs can hamper the growth of metastasising melanoma cells if the cellular messenger substance Interleukin-6 (IL-6) is present. This link was observed in a research project funded by the Austrian Science Fund FWF. In laboratory tests, statins (cholesterol-lowering agent more
Closer to the source of the itch
Psoriasis is an inflammatory skin condition that affects some 125 million people worldwide. It is characterized by itchy, scaly skin plaques. The exact cause of psoriasis is unclear. But mounting evidence implicates the immune system in the overproduction of cell-signalling molecules called cytokine more
Antibody therapy opens door to potential new treatment for HIV
The development of antiretroviral therapy, a combination of drugs that slows the replication of HIV in the body, has transformed the treatment of this infection. What was once a certain death sentence is now a chronic condition that people can live with for decades. But this therapy has drawbacks. T more
Danish researchers behind vaccine breakthrough
The next generation of vaccines may soon see the light of day, because Danish researchers have discovered a completely new and simple method which sets new standards for the development of vaccines. "The major research breakthrough is that we have created a general and user-friendly platform for the more
Vanderbilt researchers identify potent antibodies against HIV
It's been known for some time that the immune system can produce antibodies capable of "neutralizing" HIV, and stopping the AIDS-causing virus dead in its tracks. The problem is, less than a third of people produce "broadly neutralizing" antibodies in response to HIV infection and it takes a year or more
Promotion of Aggregation as a Means of Assessing the Stability of Antibody Molecules
The efficiency of antibody molecules is dependent on their stability. We introduce an assay setup where stability of antibodies is measured. Shaking stress is initiated by the FLUOstar Omega microplate reader and aggregation propensity of antibody ca more
Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications
Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diag more
Agrisera Western Blot recommendations, troubleshooting and protocol
Each antibody-antigen interaction has unique characteristics. A protocol giving good results for one antibody-antigen pair might found to be unsatisfactory for a second antibody even on the same sample. The interaction of antisera with protein epitop more
Characterizing Biotherapeutics with HPLC
As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmace more
Functional Analysis of Side Effects of Transfection Reagents in the Context of Bax-induced Apoptosis
FuGENE® HD Transfection Reagent is well-suited for studying the impact of apoptosis-inducing proteins such as bax. Transfection with FuGENE® HD Transfection Reagent produced only minimal cytotoxic side effects while maintaining a high transfection ef more
ReadyTector® is the all-in-one detection solution for Western blotting. ReadyTector® enables a fast one step immunodetection without background more
HRP-Protector™ - Diluent for long-term storage of HRP conjugates, for better stability and enhanced shelf life more
Long-term stability at 4°C. Industrial stabilizer solutions are now affordable for any laboratory. Even moist storage is possible, but with shorter shelf life. more
Immunohistochemical Evaluation of the GABAergic Neuronal System in the Prefrontal Cortex of a DI ...
Abstract The etiology of schizophrenia remains unknown. However, using molecular biological techniques, some candidate genes have been identified that might be associated with the disease. One of these candidate genes, disrupted‐in‐schizophrenia 1 (DISC1), was found in a large Scottish family wi more
Factor VIII associated with lipidic nanoparticles retains efficacy in the presence of anti‐Facto ...
Abstract Development of inhibitory antibodies against Factor VIII (FVIII) is a major challenge in Hemophilia A (HA) therapy. Such antibodies develop in nearly 30% of the patients receiving replacement FVIII, abrogating therapeutic efficacy. In this work, we evaluated whether B‐domain deleted FVI more
Rational Design of Targeted Next-Generation Carriers for Drug and Vaccine Delivery
Pattern recognition receptors on innate immune cells play an important role in guiding how cells interact with the rest of the organism and in determining the direction of the downstream immune response. Recent advances have elucidated the structure and function of these receptors, providing new opp more
Zebrafish Connexin 79.8 (Gja8a): A lens connexin used as an electrical synapse in some neurons
ABSTRACT In the mammalian central nervous system a remarkably small number of connexins is used in electrical synapses, with the majority formed from Cx36. A larger number has been detected in teleosts, with some seeming to serve restricted roles. Here we report the discovery of a new connexin e more
Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins [I ...
Oligoclonal Ig bands (OCBs) of the cerebrospinal fluid are a hallmark of multiple sclerosis (MS), a disabling inflammatory disease of the central nervous system (CNS). OCBs are locally produced by clonally expanded antigen-experienced B cells and therefore are believed to hold an important clue to t more