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Find antibodies by searching for a name or antigen and narrow down your results by defining parameters like reactivity, application, conjugate etc.
- Flow Cytometry (FC)
- Fluorescence Microscopy
- Frozen Tissue Sections
- Functional Assays (FN)
- IHC Paraffin And Frozen
- Immunochemistry (IC)
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- Immunohistochemistry (IHC)
- Immunohistochemistry, frozen sections (IH ...
- Immunohistochemistry, paraffin-embedded s ...
- Immunoprecipitation (IP)
- Intracytoplasmic Staining
- Paraffin-embededded Tissue Sections
Toward glow-in-the-dark tumors
What if you could plaster cancer cells with glowing "Here We Are" signs, so surgeons could be confident that they'd removed every last speck of a tumor? That's what Haiying Liu has in mind for his new fluorescent probe. "Doctors need to pinpoint cancer tissue, but that can be hard," said Liu, a chem more
Laser activated gold pyramids could deliver drugs, DNA into cells without harm
The ability to deliver cargo like drugs or DNA into cells is essential for biological research and disease therapy but cell membranes are very good at defending their territory. Researchers have developed various methods to trick or force open the cell membrane but these methods are limited in the t more
Antibody fights pediatric brain tumors in preclinical testing
Five types of pediatric brain cancer were safely and effectively treated in mice by an antibody that causes immune cells to engulf and eat tumors without hurting healthy brain cells, according to a new study by researchers at the Stanford University School of Medicine. The immune therapy studied con more
New method enables creation of better therapeutic antibodies
Antibodies are the foot soldiers of our immune system. These specialized, Y-shaped proteins attach to bacteria and viruses, where they either block the pathogen's activity directly, or signal the immune system's cells to destroy the invader. The second function--the ability to target invaders for de more
Novasep opensnew antibody-drug conjugate bioconjugation unit
Novasep announces that its new €11M bioconjugation facility is now operational. The greenfield facility was erected within 20 months on Novasep’s Le Mans site in France. The 2,000m2 facility features two flexible GMP production suites equipped with 10L to 400L vessels to support both clinical and co more
Verifying SPARCL Performance on the CLARIOstar Equipped for Reading at Time of Injection
SPARCL refers to an immunoassay that does not require washing steps more
Getting the Full Picture: Predicting the Aggregation Propensity of mAbs
Getting the full picture: predicting the aggregation propensity of mabs using chemical and thermal denaturation on a single, fully automated platform more
Promotion of Aggregation as a Means of Assessing the Stability of Antibody Molecules
The efficiency of antibody molecules is dependent on their stability. We introduce an assay setup where stability of antibodies is measured. Shaking stress is initiated by the FLUOstar Omega microplate reader and aggregation propensity of antibody ca more
Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications
Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diag more
Agrisera Western Blot recommendations, troubleshooting and protocol
Each antibody-antigen interaction has unique characteristics. A protocol giving good results for one antibody-antigen pair might found to be unsatisfactory for a second antibody even on the same sample. The interaction of antisera with protein epitop more
ReadyTector is the all-in-one detection solution for Western blotting. ReadyTector enables a fast one step immunodetection without background more
HRP-Protector - Diluent for long-term storage of HRP conjugates, for better stability and enhanced shelf life more
Long-term stability at 4 °C. Industrial stabilizer solutions are now affordable for any laboratory. Even moist storage is possible, but with shorter shelf life more
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Gulf War Illness patients exhibit increas ...
Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Gulf War Illness (GWI) are debilitating diseases with overlapping symptomology and there are currently no validated tests for definitive diagnosis of either syndrome. While there is evidence supporting the premise that som more
[Perspective] Developing an HIV vaccine
In 2015, 17 million HIV-infected individuals worldwide were on antiretroviral drug therapies, which are remarkably effective in suppressing the virus. Yet, 6000 people a day became newly infected, making the quest for an effective and safe HIV vaccine a major global priority. However, developing a v more
Bach2 regulates AID‐mediated immunoglobulin gene conversion and somatic hypermutation in DT40 B ...
The transcription factor Bach2 is required for germinal centre formation, somatic hypermutation (SHM) and class‐switch recombination (CSR) of immunoglobulins. SHM and CSR are initiated by activation‐induced cytidine deaminase (AID) which has potential to induce human B cell lymphoma. To understand more
Synergy between the classical and alternative pathways of complement is essential for conferring ...
by Ajitanuj Rattan, Shailesh D. Pawar, Renuka Nawadkar, Neeraja Kulkarni, Girdhari Lal, Jayati Mullick, Arvind Sahu The pandemic influenza A(H1N1) 2009 virus caused significant morbidity and mortality worldwide thus necessitating the need to understand the host factors that influence its control. more
Efficient Preparation of Site-Specific Antibody–Drug Conjugates Using Cysteine Insertion
Antibody–drug conjugates (ADCs) are a class of biopharmaceuticals that combine the specificity of antibodies with the high-potency of cytotoxic drugs. Engineering cysteine residues in the antibodies using mutagenesis is a common method to prepare site-specific ADCs. With this approach, solvent acces more