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Find antibodies by searching for a name or antigen and narrow down your results by defining parameters like reactivity, application, conjugate etc.
- Flow Cytometry (FC)
- Fluorescence Microscopy
- Frozen Tissue Sections
- Functional Assays (FN)
- Immunochemistry (IC)
- Immunocytochemistry (ICC)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Immunohistochemistry, frozen sections (IH ...
- Immunohistochemistry, paraffin-embedded s ...
- Immunoprecipitation (IP)
- Paraffin-embededded Tissue Sections
An antibody that can attack HIV in new ways
Proteins called broadly neutralizing antibodies (bNAbs) are a promising key to the prevention of infection by HIV, the virus that causes AIDS. bNAbs have been found in blood samples from some HIV patients whose immune systems can naturally control the infection. These antibodies may protect a patien more
Cirrhosis, antibodies increase risk of poor outcome for autoimmune hepatitis patients
New research reports that cirrhosis at first diagnosis and antibodies for the soluble liver antigen/liver pancreas antigen (SLA/LP) are major risk factors for poor short- and long-term outcome in patients with autoimmune hepatitis. Results also found that patients diagnosed in childhood were at high more
Scientists engineer designer proteins that control enzyme activity
Scientists have developed a novel approach to control the activity of enzymes through the use of synthetic, antibody-like proteins known as monobodies. A team led by Shohei Koide, PhD, professor of biochemistry and molecular biophysics, was able to change the specificity of an enzyme without alterin more
MorphoSys and G7 Therapeutics Sign Alliance to Develop Antibody Therapeutics
MorphoSys AG and G7 Therapeutics AG announced that they have signed an agreement to collaborate on novel antibody therapeutics targeting G protein-coupled receptors (GPCRs) and potentially other disease-related transmembrane proteins such as ion channels. Under the terms of the agreement, G7 Therape more
Georg-August-University Göttingen, Universitätsmedizin and MRC Technology collaborate to develop ...
Georg-August-University Göttingen (UMG) and MRC Technology (MRCT) have signed an exclusive license agreement for the development of a novel therapy for neurodegenerative diseases based on antibody targeting amyloid beta peptides 4-x. The aim is to develop a therapy for Alzheimer's Disease (AD).The l more
Promotion of Aggregation as a Means of Assessing the Stability of Antibody Molecules
The efficiency of antibody molecules is dependent on their stability. We introduce an assay setup where stability of antibodies is measured. Shaking stress is initiated by the FLUOstar Omega microplate reader and aggregation propensity of antibody ca more
Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications
Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diag more
Characterizing Biotherapeutics with HPLC
As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmace more
Agrisera Western Blot recommendations, troubleshooting and protocol
Each antibody-antigen interaction has unique characteristics. A protocol giving good results for one antibody-antigen pair might found to be unsatisfactory for a second antibody even on the same sample. The interaction of antisera with protein epitop more
Functional Analysis of Side Effects of Transfection Reagents in the Context of Bax-induced Apoptosis
FuGENE® HD Transfection Reagent is well-suited for studying the impact of apoptosis-inducing proteins such as bax. Transfection with FuGENE® HD Transfection Reagent produced only minimal cytotoxic side effects while maintaining a high transfection ef more
ReadyTector® is the all-in-one detection solution for Western blotting. ReadyTector® enables a fast one step immunodetection without background more
Long-term stability at 4°C. Industrial stabilizer solutions are now affordable for any laboratory. Even moist storage is possible, but with shorter shelf life. more
EndoS and EndoS2 hydrolyze Fc-glycans on therapeutic antibodies with different glycoform selecti ...
Enzymes that affect glycoproteins of the human immune system, and thereby modulate defense responses, are abundant among bacterial pathogens. Two endoglycosidases from the human pathogen Streptococcus pyogenes, EndoS and EndoS2, have recently been shown to hydrolyze N-linked glycans of human immuno more
Neuronal labeling patterns in the spinal cord of adult transgenic Zebrafish
ABSTRACT We describe neuronal patterns in the spinal cord of adult zebrafish. We studied the distribution of cells and processes in the three spinal regions reported in the literature: the 8th vertebra used as a transection injury site, the 15th vertebra mainly used for motor cell recordings and more
Measles surveillance in Taiwan, 2012–2014: Changing epidemiology, immune response and circulatin ...
Abstract In Taiwan, although the coverage rate of two doses of measles‐containing vaccine has been maintained at over 95% since 2001, measles outbreaks occurred in 2002, 2009 and 2011. The present study reports that 43 cases were confirmed by laboratory testing in Taiwan in 2012‐2014 and that a more
Efficient preparation and site‐directed immobilization of VHH antibodies by genetic fusion of po ...
Abstract A PMMA‐binding peptide (PMMA‐tag) was genetically fused with the C‐terminal region of an anti‐human chorionic gonadotropin (hCG) single‐domain antibody (VHH). It was over‐expressed in an insoluble fraction of E. coli cells, and recovered in the presence of 8 M urea via one‐step IMAC pur more
Differential phagocytosis of Leishmania mexicana promastigotes and amastigotes by monocyte‐deriv ...
Abstract Leishmania species are dimorphic protozoan parasites that live and replicate in the gut of sand flies as promastigotes or as amastigotes in mammalian hosts. There are differences in the phagocytosis of promastigotes and amastigotes among different cells of the immune response, such as more