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Find antibodies by searching for a name or antigen and narrow down your results by defining parameters like reactivity, application, conjugate etc.
- Flow Cytometry (FC)
- Frozen Tissue Sections
- Functional Assays (FN)
- Immunochemistry (IC)
- Immunocytochemistry (ICC)
- Immunofluorescence (IF)
- Immunohistochemistry ((frozen) (IHC(F))
- Immunohistochemistry (frozen)
- Immunohistochemistry (frozen) (IHC(F))
- Immunohistochemistry (IHC)
- Immunohistochemistry (IHC)(F
- Immunohistochemistry (IHC)(P)
- Immunohistochemistry, frozen sections (IH ...
- Immunoprecipitation (IP)
- Western Blot (WB)
PROGEN acquires EuroProxima’s research antibodies
PROGEN Biotechnik GmbH has recently acquired the research antibody line of the Dutch company EuroProxima B.V., a global provider of immunobiological test systems. The deal encompasses about 190 products that supplement PROGEN’s portfolio of proprietary immunochemicals. The purchase is part of PROGEN more
Steering the Immune Defense against Fungal Pathogens
Fungal infections represent an increasing health crisis, especially for immune-deficient patients. Scientists report that specific help could be provided by small-molecule immunotherapeutics with novel mechanism of action. They developed small bifunctional molecules that simultaneously bind both chi more
Explaining why myasthenia patients relapse after treatment
A new Yale-led study helps explain why some myasthenia gravis (MG) patients relapse after initially responding to a drug called rituximab, commonly used to treat the incurable autoimmune disease marked by muscle weakness and fatigue. In patients with MG, B cells — a subset of white cells that produc more
FDA approval brings first gene therapy to the United States
The U.S. Food and Drug Administration issued a historic action today making the first gene therapy available in the United States, ushering in a new approach to the treatment of cancer and other serious and life-threatening diseases. The FDA approved Kymriah (tisagenlecleucel) for certain pediatric more
Expanding the reach of therapeutic antibodies
A group of researchers has developed an approach to efficiently produce antibodies that can bind to two different target molecules simultaneously, a long-desired innovation in the field of cancer immunotherapy. Antibodies are proteins produced by the immune system that specialize in recognizing and more
Verifying SPARCL Performance on the CLARIOstar Equipped for Reading at Time of Injection
SPARCL refers to an immunoassay that does not require washing steps more
Getting the Full Picture: Predicting the Aggregation Propensity of mAbs
Getting the full picture: predicting the aggregation propensity of mabs using chemical and thermal denaturation on a single, fully automated platform more
Promotion of Aggregation as a Means of Assessing the Stability of Antibody Molecules
The efficiency of antibody molecules is dependent on their stability. We introduce an assay setup where stability of antibodies is measured. Shaking stress is initiated by the FLUOstar Omega microplate reader and aggregation propensity of antibody ca more
Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications
Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diag more
Agrisera Western Blot recommendations, troubleshooting and protocol
Each antibody-antigen interaction has unique characteristics. A protocol giving good results for one antibody-antigen pair might found to be unsatisfactory for a second antibody even on the same sample. The interaction of antisera with protein epitop more
ReadyTector is the all-in-one detection solution for Western blotting. ReadyTector enables a fast one step immunodetection without background more
HRP-Protector - Diluent for long-term storage of HRP conjugates, for better stability and enhanced shelf life more
Long-term stability at 4 °C. Industrial stabilizer solutions are now affordable for any laboratory. Even moist storage is possible, but with shorter shelf life more
Multivalent interactions between streptavidin-based pretargeting fusion proteins and cell recept ...
Publication date: Available online 9 September 2017 Source:Acta Biomaterialia Author(s): Christina L. Parker, Qi Yang, Bing Yang, Justin D. McCallen, Steven I. Park, Samuel K. Lai Pretargeting represents a promising strategy to enhance delivery of nanoparticles. The strategy involv more
On the road to replacing invasive testing with cell‐based NIPT: five clinical cases with aneuplo ...
Abstract Objective Trophoblastic fetal cells harvested from maternal blood have the capacity to be used for copy number analyses in a non‐invasive prenatal test (cbNIPT). Potentially this will result in increased resolution for detection of subchromosomal aberrations due to high quality DNA no more
The classic signalling and trans‐signalling of interleukin‐6 are both injurious in podocyte unde ...
Abstract Interleukin‐6 (IL‐6) is a multifunctional cytokine that employs IL‐6 classic and trans‐signalling pathways, and these two signal channels execute different or even opposite effects in certain diseases. As a cardinal event of diabetic kidney disease (DKD), whether the podocyte abnormalit more
Melanocortin receptor subtypes are expressed on cells in the oligodendroglial lineage and signal ...
Abstract ACTH, a melanocortin peptide used to treat multiple sclerosis (MS) relapses, acts by stimulating adrenal corticosteroid (CS) production via melanocortin receptor 2 (MC2R), but it may also exert a therapeutic effect independent of CS by stimulating other melanocortin receptors (MCR) dist more
HTLV‐1 Intrafamilial Transmission Among Japanese Immigrants in Brazil
ABSTRACT Human T‐lymphotropic virus type 1 (HTLV‐1) is the etiological agent of adult T‐cell leukemia/lymphoma and HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP). The aim of this study was to investigate the intrafamilial transmission of HTLV‐1 among Japanese immigrants and more