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Find antibodies by searching for a name or antigen and narrow down your results by defining parameters like reactivity, application, conjugate etc.
- Flow Cytometry (FC)
- Fluorescence Microscopy
- Frozen Tissue Sections
- Functional Assays (FN)
- IHC Paraffin And Frozen
- Immunochemistry (IC)
- Immunocytochemistry (ICC)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Immunohistochemistry, frozen sections (IH ...
- Immunohistochemistry, paraffin-embedded s ...
- Immunoprecipitation (IP)
- Intracytoplasmic Staining
- Paraffin-embededded Tissue Sections
Broadly neutralizing HIV antibodies pave the way for vaccine
A small number of people infected with HIV produce antibodies with an amazing effect: Not only are the antibodies directed against the own virus strain, but also against different sub-types of HIV that circulate worldwide. Researchers from the University of Zurich and University Hospital Zurich now more
Subsidiary Heidelberg Pharma contracts Celonic
WILEX AG, announced that its subsidiary Heidelberg Pharma, has signed an agreement with Celonic AG, Basel, Switzerland, a specialist in the development and manufacturing of biologics (CDMO). This agreement includes cell line development and the production of non-GMP and GMP (Good Manufacturing Pract more
Osteoporosis: Antibody crystallised
Inhibiting a protein called Sclerostin could probably help treating the bone-loss disease osteoporosis. New findings at the University of Würzburg could stimulate this research. Osteoporosis particularly affects elderly women: the bone’s structure weakens and the risk of suffering fractures rises. more
Antibody reduces harmful brain amyloid plaques in Alzheimer's patients
Aducanumab, an antibody developed by the University of Zurich, has been shown to trigger a meaningful reduction of harmful beta-amyloid plaques in patients with early-stage Alzheimer's disease. These protein deposits in the brain are a classic sign of Alzheimer's disease and contribute to the progre more
BioInvent extends manufacturing services contract with major global pharmaceutical client
BioInvent International announced that it has signed an extended contract for manufacturing services with one of its current customers, a major global pharmaceutical client. The extension covers services for one of the products in the pharmaceutical company’s development portfolio. Michael Oredsson, more
Promotion of Aggregation as a Means of Assessing the Stability of Antibody Molecules
The efficiency of antibody molecules is dependent on their stability. We introduce an assay setup where stability of antibodies is measured. Shaking stress is initiated by the FLUOstar Omega microplate reader and aggregation propensity of antibody ca more
Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications
Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diag more
Agrisera Western Blot recommendations, troubleshooting and protocol
Each antibody-antigen interaction has unique characteristics. A protocol giving good results for one antibody-antigen pair might found to be unsatisfactory for a second antibody even on the same sample. The interaction of antisera with protein epitop more
Characterizing Biotherapeutics with HPLC
As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmace more
Functional Analysis of Side Effects of Transfection Reagents in the Context of Bax-induced Apoptosis
FuGENE® HD Transfection Reagent is well-suited for studying the impact of apoptosis-inducing proteins such as bax. Transfection with FuGENE® HD Transfection Reagent produced only minimal cytotoxic side effects while maintaining a high transfection ef more
ReadyTector is the all-in-one detection solution for Western blotting. ReadyTector enables a fast one step immunodetection without background more
HRP-Protector - Diluent for long-term storage of HRP conjugates, for better stability and enhanced shelf life more
Long-term stability at 4 °C. Industrial stabilizer solutions are now affordable for any laboratory. Even moist storage is possible, but with shorter shelf life more
Maternally Derived Immunity Extends Swine Influenza A Virus Persistence within Farrow-to-Finish ...
by Charlie Cador, Nicolas Rose, Lander Willem, Mathieu Andraud Swine Influenza A Viruses (swIAVs) have been shown to persist in farrow-to-finish pig herds with repeated outbreaks in successive batches, increasing the risk for respiratory disorders in affected animals and being a threat for public more
Simultaneous Quantification of Anticardiolipin IgG and IgM by Time Resolved Fluoroimmunoassay
by Zhigang Hu, Xiaoying Jing, Jie Liu, Mei Li, Yan Ye, Yu Chen The autoimmune disease antiphospholipid syndrome (APS) is characterized by the presence of anticardiolipin antibodies (aCL), along with anti-β2-glycoprotein I (β2GPI) antibodies and lupus anticoagulant (LA). In this study, we develope more
Type 2 diabetes alters mesenchymal stem cell secretome composition and angiogenic properties
Abstract This study aimed at characterizing the impact of type 2 diabetes mellitus (T2DM) on the bone marrow mesenchymal stem cell (BMMSC) secretome and angiogenic properties. BMMSCs from Zucker diabetic fatty rats (ZDF) (a T2DM model) and Zucker LEAN littermates (control) were cultured. The sup more
A novel flow cytometric method for the simultaneous detection of antibodies against platelet, ly ...
Abstract Background: Platelet or neutrophil antibodies (Ab) detected by an indirect method need to be further investigated to confirm that they are HLA (lymphocyte)‐specific. This can only be determined by the assessment of lymphocytes from the same donor. We have developed an improved flow cyto more
[Research Article] Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive ...
### INTRODUCTION To combat invading pathogens, cells develop an adaptive immune response by changing their own genetic information. In vertebrates, the generation of genetic variation (somatic hypermutation) is an essential process for diversification and affinity maturation of antibodies that func more