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Find antibodies by searching for a name or antigen and narrow down your results by defining parameters like reactivity, application, conjugate etc.
- Flow Cytometry (FC)
- Fluorescence Microscopy
- Frozen Tissue Sections
- Functional Assays (FN)
- IHC Paraffin And Frozen
- Immunochemistry (IC)
- Immunocytochemistry (ICC)
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- Immunohistochemistry (IHC)
- Immunohistochemistry, frozen sections (IH ...
- Immunohistochemistry, paraffin-embedded s ...
- Immunoprecipitation (IP)
- Intracytoplasmic Staining
- Paraffin-embededded Tissue Sections
Going viral: Insights on Zika
The Zika virus (ZIKV) is not a new contagion; researchers have known about the virus since the 1950s. However, not much was known about the virus until recent outbreaks cropped up with debilitating impacts. While searching for targets that could be used to generate antibodies against the virus, biol more
New, carbon-nanotube tool for ultra-sensitive virus detection and identification
A new tool that uses a forest-like array of vertically-aligned carbon nanotubes that can be finely tuned to selectively trap viruses by their size can increase the detection threshold for viruses and speed the process of identifying newly-emerging viruses. "Detecting viruses early in an infection be more
Vaccine may help diseases in animals, people meet their match
A newly patented vaccine by Kansas State University researchers could be good news for meat consumers. The researchers developed a solution that could provide effective, antibiotic-free prevention of Fusobacterium necrophorum infection. The bacterium afflicts sheep and cattle with liver abscesses, c more
Respiratory tract bacterium uncovered as trigger for serious nervous system disease
Guillain-Barré syndrome (GBS) is an acute life-threatening disease of the nervous system that leads to sensory disturbances and acute flaccid paralysis. A group of researchers involving the University of Zurich has now shown for the first time that bacteria, which often cause pneumonia, can trigger more
Broadly neutralizing HIV antibodies pave the way for vaccine
A small number of people infected with HIV produce antibodies with an amazing effect: Not only are the antibodies directed against the own virus strain, but also against different sub-types of HIV that circulate worldwide. Researchers from the University of Zurich and University Hospital Zurich now more
Getting the Full Picture: Predicting the Aggregation Propensity of mAbs
Getting the full picture: predicting the aggregation propensity of mabs using chemical and thermal denaturation on a single, fully automated platform more
Promotion of Aggregation as a Means of Assessing the Stability of Antibody Molecules
The efficiency of antibody molecules is dependent on their stability. We introduce an assay setup where stability of antibodies is measured. Shaking stress is initiated by the FLUOstar Omega microplate reader and aggregation propensity of antibody ca more
Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications
Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diag more
Agrisera Western Blot recommendations, troubleshooting and protocol
Each antibody-antigen interaction has unique characteristics. A protocol giving good results for one antibody-antigen pair might found to be unsatisfactory for a second antibody even on the same sample. The interaction of antisera with protein epitop more
Characterizing Biotherapeutics with HPLC
As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmace more
ReadyTector is the all-in-one detection solution for Western blotting. ReadyTector enables a fast one step immunodetection without background more
HRP-Protector - Diluent for long-term storage of HRP conjugates, for better stability and enhanced shelf life more
Long-term stability at 4 °C. Industrial stabilizer solutions are now affordable for any laboratory. Even moist storage is possible, but with shorter shelf life more
Positive Selection Drives Evolution at the Host–Filovirus Interaction Surface
Filovirus infection is mediated by engagement of the surface-exposed glycoprotein (GP) by its cellular receptor, NPC1 (Niemann-Pick C1). Two loops in the C domain of NPC1 (NPC1-C) bind filovirus GP. Herein, we show that filovirus GP and NPC1-C evolve under mutual selective pressure. Analysis of a l more
Systemic lupus erythematosus: molecular cloning and analysis of recombinant monoclonal kappa lig ...
It was shown previously that approximately 30±5% of antibodies against myelin basic protein (MBP) and DNA of patients with systemic lupus erythematosus (SLE) and multiple sclerosis (MS) possess catalytic activities and play an important negative role in the pathogenesis of MS and SLE. An immunoglobu more
Impact of Serum Antibodies to HPV Serotypes 6, 11, 16, and 18 to Risks of Subsequent Genital HPV ...
Naturally induced serum antibodies against human papillomavirus (HPV) may affect risks of subsequent incident genital infections by HPV 6, 11, 16, or 18 in men. In this study, we examined the hypothesis by following 4,123 healthy men every 6 months (median follow-up time, 4.1 years). HPV antibodies more
Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases
Abstract Anti‐angiogenic therapies using biological molecules that neutralize vascular endothelial growth factor‐A (VEGF‐A) have revolutionized treatment of retinal vascular diseases including age‐related macular degeneration (AMD). This study reports preclinical assessment of a strategy to enha more
Progesterone from maternal circulation binds to progestin receptors in fetal brain
Abstract Steroid hormones activate nuclear receptors which, as transcription factors, can regulate critical aspects of neural development. Many regions of the rat forebrain, midbrain and hindbrain express progestin receptors (PR) during perinatal life, suggesting that progesterone may play an im more