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ANTIBODIES

Antibodies

Find antibodies by searching for a name or antigen and narrow down your results by defining parameters like reactivity, application, conjugate etc.

News about antibodies
  • WILEX subsidiary Heidelberg Pharma extends research collaboration with Roche

    WILEX AG announced that WILEX subsidiary Heidelberg Pharma and Roche extended the existing 2013 licence agreement to apply the antibody drug conjugate (ADC) technology for the further development of Roche antibodies. The aim is to identify and develop novel AntibodyTargeted Amanitin Conjugates (ATAC more

  • Chemists recruit anthrax to deliver cancer drugs

    Bacillus anthracis bacteria have very efficient machinery for injecting toxic proteins into cells, leading to the potentially deadly infection known as anthrax. A team of MIT researchers has now hijacked that delivery system for a different purpose: administering cancer drugs. "Anthrax toxin is a pr more

  • Mechanism of Parkinson's spread demonstrated

    An international, interdisciplinary group of researchers led by Gabor G. Kovacs from the Clinical Institute of Neurology at the MedUni Vienna has demonstrated, through the use of a new antibody, how Parkinson's disease spreads from cell to cell in the human brain.Until now, this mechanism has only b more

  • Merck Serono and Sutro Biopharma to Partner on Development of Antibody Drug Conjugates

    Merck Serono and Sutro Biopharma, San Francisco, a biopharmaceutical company developing antibody drug conjugates and bispecific antibodies, announced a collaboration and license agreement to develop antibody drug conjugates (ADCs). ADCs are composed of an antibody linked to a cytotoxic drug. The ant more

  • MorphoSys Receives Research Grant to Develop Novel Therapeutic Antibodies Targeting GPCRs

    MorphoSys AG announced the receipt of a grant of up to EUR 1 million from the German Federal Ministry of Education and Research (BMBF), comprising funding for two of its therapeutic antibody programs. The funding will support the company in developing Ylanthia antibodies against two undisclosed G pr more

White paper on antibodies
  • Promotion of Aggregation as a Means of Assessing the Stability of Antibody Molecules

    The efficiency of antibody molecules is dependent on their stability. We introduce an assay setup where stability of antibodies is measured. Shaking stress is initiated by the FLUOstar Omega microplate reader and aggregation propensity of antibody candidates is measured in 96-well format more

  • Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications

    Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diagnostics more

  • Agrisera Western Blot recommendations, troubleshooting and protocol

    Each antibody-antigen interaction has unique characteristics. A protocol giving good results for one antibody-antigen pair might found to be unsatisfactory for a second antibody even on the same sample. The interaction of antisera with protein epitopes in Western blot dependens upon a number of factors, all contributing to the final signal/noise ratio. Knowledge and control of those factors allows for modifications and optimization of the procedure. Polyclonal antibodies (serum or IgY-fractions from egg yolk) usually contain a number of different antibodies interacting independently with different epitopes on the target used for immunization. This number is limited for peptide-antigens but if recombinant or native proteins have been used for immunization the signal obtained has to be regarded as cumulative (=caused by several different types of antibodies present in the serum/IgY used) more

  • Characterizing Biotherapeutics with HPLC

    As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmaceutical to approval at the regulatory agencies. The introduction of the first so-called biosimilars in Europe further increased the demand for highly efficient analysis methods. The continuous development of new stationary phases for the common modes of biochromatography, such as size exclusion, ion exchange and hydrophilic interaction chromatography support biochemists in increasing lab productivity and establishing high-throughput HPLC analysis not only for small molecules but also for large biopolymers more

  • Functional Analysis of Side Effects of Transfection Reagents in the Context of Bax-induced Apoptosis

    FuGENE® HD Transfection Reagent is well-suited for studying the impact of apoptosis-inducing proteins such as bax. Transfection with FuGENE® HD Transfection Reagent produced only minimal cytotoxic side effects while maintaining a high transfection efficiency. In contrast, cytotoxicity, and off-target effects of the other commercially available transfection reagents tested made it impossible to distinguish the impact of the bax protein from the impact of the transfection reagent itself more

Products for antibodies

The all-in-one Solution for Western blotting

ReadyTector® is the all-in-one detection solution for Western blotting. ReadyTector® enables a fast one step immunodetection without background more

Your antibodies will be happy about it!

Long-term stability at 4°C without inconvenient freezing and thawing? Industrial stabilizer solutions are now affordable for any laboratory more

Protection for antibodies and antigens coated on plates!

Long-term stability at 4°C. Industrial stabilizer solutions are now affordable for any laboratory. Even moist storage is possible, but with shorter shelf life. more

Publications on antibodies
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