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Find antibodies by searching for a name or antigen and narrow down your results by defining parameters like reactivity, application, conjugate etc.
- Flow Cytometry (FC)
- Fluorescence Microscopy
- Frozen Tissue Sections
- Functional Assays (FN)
- Immunochemistry (IC)
- Immunocytochemistry (ICC)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Immunohistochemistry, frozen sections (IH ...
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- Immunoprecipitation (IP)
- Paraffin-embededded Tissue Sections
Georg-August-University Göttingen, Universitätsmedizin and MRC Technology collaborate to develop ...
Georg-August-University Göttingen (UMG) and MRC Technology (MRCT) have signed an exclusive license agreement for the development of a novel therapy for neurodegenerative diseases based on antibody targeting amyloid beta peptides 4-x. The aim is to develop a therapy for Alzheimer's Disease (AD).The l more
PNAS Paper Details Efficacy of a Potent, Fully Human Antibody for the Treatment of MERS
Humabs BioMed SA announced that Proceedings of the National Academy of Sciences (PNAS) has published a paper describing the isolation and characterization of a potent antibody from memory B-cells of a patient recovering from an infection with coronavirus (CoV) and the resulting Middle East Respirato more
Discovery of Cellular Mechanism of Action of tACPA in Rheumatoid Arthritis
ModiQuest B.V announces that it has discovered the cellular mechanism of action of its therapeutic anti-citrullinated protein lead antibodies (tACPA) for the treatment of rheumatoid arthritis (RA) and other diseases. To accelerate tACPA development towards clinical Proof of Concept, facilitate fundi more
Antibody response linked to lower mother-to-child HIV transmission
How most babies are protected from acquiring HIV from their infected mothers has been a matter of scientific controversy. Now researchers at Duke Medicine provide new data identifying an antibody response that had long been discounted as inadequate to confer protection.Mother-to-child transmissions more
HER-Vaxx Re-Formulation Shows Dramatic Ten-Fold Increase in Antibodies and Early Onset of Response
Imugene Limited, a clinical stage immuno-oncology company developing HER-2 positive gastric and breast cancer immunotherapies, announces that Imugene’s lead candidate HER-Vaxx has demonstrated a powerful increase in the production of cancer fighting antibodies in preclinical animal model testing. Th more
Promotion of Aggregation as a Means of Assessing the Stability of Antibody Molecules
The efficiency of antibody molecules is dependent on their stability. We introduce an assay setup where stability of antibodies is measured. Shaking stress is initiated by the FLUOstar Omega microplate reader and aggregation propensity of antibody candidates is measured in 96-well format more
Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications
Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diag more
Agrisera Western Blot recommendations, troubleshooting and protocol
Each antibody-antigen interaction has unique characteristics. A protocol giving good results for one antibody-antigen pair might found to be unsatisfactory for a second antibody even on the same sample. The interaction of antisera with protein epitop more
Characterizing Biotherapeutics with HPLC
As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmace more
Functional Analysis of Side Effects of Transfection Reagents in the Context of Bax-induced Apoptosis
FuGENE® HD Transfection Reagent is well-suited for studying the impact of apoptosis-inducing proteins such as bax. Transfection with FuGENE® HD Transfection Reagent produced only minimal cytotoxic side effects while maintaining a high transfection ef more
ReadyTector® is the all-in-one detection solution for Western blotting. ReadyTector® enables a fast one step immunodetection without background more
Long-term stability at 4°C. Industrial stabilizer solutions are now affordable for any laboratory. Even moist storage is possible, but with shorter shelf life. more
Investigation of the protective properties of glycosylphosphatidylinositol-based vaccine candida ...
Vaccination against the ubiquitous parasite Toxoplasma gondii would provide the most efficient prevention against toxoplasmosis-related congenital, brain and eye diseases in humans. We investigated the immune response elicited by pathogen-specific glycosylphosphatidylinositol (GPI) glycoconjugates more
Isolation and characterization of monoclonal antibodies specific for chondroitin sulfate E
Chondroitin sulfate E (CSE) is a polysaccharide containing mainly disaccharide units of d-glucuronic acid (GlcA) and 4,6-O-disulfated N-acetyl-d-galactosamine (GalNAc) residues (E-unit) in the amount of ~60%. CSE is involved in many biological and pathological processes. In this study, we establish more
Antibody recognition of carbohydrate epitopes
Carbohydrate antigens are valuable as components of vaccines for bacterial infectious agents and human immunodeficiency virus (HIV), and for generating immunotherapeutics against cancer. The crystal structures of anti-carbohydrate antibodies in complex with antigen reveal the key features of antige more
Homogeneously modified immunoglobulin domains for therapeutic application
Publication date: October 2015 Source:Current Opinion in Chemical Biology, Volume 28 Author(s): Tao Liu, Juanjuan Du, Xiaozhou Luo, Peter G Schultz, Feng Wang The field of therapeutic antibodies has been revolutionized over the past decade, led by the development of novel antibody-mo more
Disruption of the lamin A and matrin-3 interaction by myopathic LMNA mutations
The nuclear face of the nuclear membrane is enriched with the intermediate filament protein lamin A. Mutations in LMNA, the gene encoding lamin A, lead to a diverse set of inherited conditions including myopathies that affect both the heart and skeletal muscle. To gain insight about lamin A protein more