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Find antibodies by searching for a name or antigen and narrow down your results by defining parameters like reactivity, application, conjugate etc.
- Flow Cytometry (FC)
- Frozen Tissue Sections
- Functional Assays (FN)
- Immunochemistry (IC)
- Immunocytochemistry (ICC)
- Immunofluorescence (IF)
- Immunohistochemistry ((frozen) (IHC(F))
- Immunohistochemistry (frozen)
- Immunohistochemistry (frozen) (IHC(F))
- Immunohistochemistry (IHC)
- Immunohistochemistry (IHC)(F
- Immunohistochemistry (IHC)(P)
- Immunohistochemistry, frozen sections (IH ...
- Immunoprecipitation (IP)
- Western Blot (WB)
Targeting blood vessels to improve cancer immunotherapy
EPFL scientists have improved the efficacy of cancer immunotherapy by blocking two proteins that regulate the growth of tumor blood vessels. Cancer immunotherapy aims to enhance or restore the ability of the patient's immune system - namely T cells - to recognize and attack cancer. But tumors use se more
New method could deliver DNA-based vaccines in pill form
A microscopic corn-and-shrimp cocktail could eventually make DNA-based vaccinations and cancer-treating gene therapies an easier pill to swallow, according to new research from the University of Nebraska-Lincoln. In a recent study, the researchers demonstrated that nesting a specialized nanoparticle more
World's first protective antibodies against Marburg virus developed
A team of scientists around Professor Michael Hust from the Institute of Biochemistry, Biotechnology and Bioinformatics of the Technische Universität Braunschweig developed successfully a panel of antibodies against highly-pathogenic Marburg virus. These are the worldwide first recombinant antibodie more
Toward glow-in-the-dark tumors
What if you could plaster cancer cells with glowing "Here We Are" signs, so surgeons could be confident that they'd removed every last speck of a tumor? That's what Haiying Liu has in mind for his new fluorescent probe. "Doctors need to pinpoint cancer tissue, but that can be hard," said Liu, a chem more
Laser activated gold pyramids could deliver drugs, DNA into cells without harm
The ability to deliver cargo like drugs or DNA into cells is essential for biological research and disease therapy but cell membranes are very good at defending their territory. Researchers have developed various methods to trick or force open the cell membrane but these methods are limited in the t more
Verifying SPARCL Performance on the CLARIOstar Equipped for Reading at Time of Injection
SPARCL refers to an immunoassay that does not require washing steps more
Getting the Full Picture: Predicting the Aggregation Propensity of mAbs
Getting the full picture: predicting the aggregation propensity of mabs using chemical and thermal denaturation on a single, fully automated platform more
Promotion of Aggregation as a Means of Assessing the Stability of Antibody Molecules
The efficiency of antibody molecules is dependent on their stability. We introduce an assay setup where stability of antibodies is measured. Shaking stress is initiated by the FLUOstar Omega microplate reader and aggregation propensity of antibody ca more
Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications
Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diag more
Agrisera Western Blot recommendations, troubleshooting and protocol
Each antibody-antigen interaction has unique characteristics. A protocol giving good results for one antibody-antigen pair might found to be unsatisfactory for a second antibody even on the same sample. The interaction of antisera with protein epitop more
ReadyTector is the all-in-one detection solution for Western blotting. ReadyTector enables a fast one step immunodetection without background more
HRP-Protector - Diluent for long-term storage of HRP conjugates, for better stability and enhanced shelf life more
Long-term stability at 4 °C. Industrial stabilizer solutions are now affordable for any laboratory. Even moist storage is possible, but with shorter shelf life more
Human IgG3 with extended half-life does not improve Fc-gamma receptor-mediated cancer antibody t ...
by Rens Braster, Simran Grewal, Remco Visser, Helga K. Einarsdottir, Marjolein van Egmond, Gestur Vidarsson, Marijn Bögels Background Current anti-cancer therapeutic antibodies that are used in the clinic are predominantly humanized or fully human immunoglobulin G1 (IgG1). These antibodies bind w more
A nationwide seroprevalence screening for West Nile virus and Tick‐borne encephalitis virus in t ...
Abstract To assess local circulation and risk for human infections with West Nile virus (WNV) and Tick‐borne encephalitis virus (TBEV) in Bulgaria, a nationwide seroprevalence study was conducted. In total, 1451 residents of all 28 districts in Bulgaria were tested for WNV‐specific and TBEV‐spe more
Antibody-Drug Conȷugates Bearing Pyrrolobenzodiazepine or Tubulysin Payloads Are Immunomodulator ...
Immunogenic cell death (ICD) is the process by which certain cytotoxic drugs induce apoptosis of tumor cells in a manner that stimulates the immune system. In this study, we investigated whether antibody–drug conjugates (ADCS) conjugated with pyrrolobenzodiazepine dimer (PBD) or tubulysin payloads i more
Higher viral load and genetic diversity of HIV‐1 in the seminal compartments than in the blood o ...
ABSTRACT To date, there have been no reports characterizing the Human Immunodeficiency Virus‐1 (HIV‐1) in the semen of Chinese men having sex with men (MSM) with early infection of HIV‐1.We examined genetic diversity and viral load of HIV‐1 in the seminal compartments and blood of Chinese MSM w more
Tug of war with anti–PD-1
Cancer Antibodies against immune checkpoint proteins such as programmed cell death 1 (PD-1) are gaining increasing prominence in cancer treatment, but these promising therapeutics do not always work. To be effective in preventing T cells from becoming exhausted, antibodies against PD-1 must remain more