To use all functions of this page, please activate cookies in your browser.
With an accout for my.bionity.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
Find antibodies by searching for a name or antigen and narrow down your results by defining parameters like reactivity, application, conjugate etc.
- Flow Cytometry (FC)
- Fluorescence Microscopy
- Frozen Tissue Sections
- Functional Assays (FN)
- IHC Paraffin And Frozen
- Immunochemistry (IC)
- Immunocytochemistry (ICC)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Immunohistochemistry, frozen sections (IH ...
- Immunohistochemistry, paraffin-embedded s ...
- Immunoprecipitation (IP)
- Intracytoplasmic Staining
- Paraffin-embededded Tissue Sections
New link discovered between class of rogue autoantibodies and poor health outcomes
Results of a new study led by Johns Hopkins researchers offer new evidence for a strong link between angiotensin receptor autoantibodies and increased risk of frailty. In a report on the work the team says a large class of common blood pressure drugs that target the angiotensin receptor, called angi more
Drug delivery modification sidesteps allergic responses
Biomedical engineers at Duke University have reconfigured a popular drug-delivery technology to evade immune responses that have halted some clinical trials. Polyethylene glycol, commonly known as PEG, is a polymer commonly found in commercial products from toothpaste to cosmetics, and also in pharm more
Catching molecular dance moves in slow motion by adding white noise
In extreme slow-motion, a molecule of medicine entering a cell receptor would look a little like a Soyuz space capsule docking at the International Space Station. It would brake here, boost there; rotate, translate and then, with a light jolt, lock into place. In real time, large molecules interact more
New procedure for producing safe and more effective vaccines
A consortium of four Fraunhofer Institutes (the Fraunhofer Institute for Cell Therapy and Immunology IZI, Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, Fraunhofer Institute for Manufacturing Engineering and Automation IPA, and the Fraunhofer Institute for Int more
Going viral: Insights on Zika
The Zika virus (ZIKV) is not a new contagion; researchers have known about the virus since the 1950s. However, not much was known about the virus until recent outbreaks cropped up with debilitating impacts. While searching for targets that could be used to generate antibodies against the virus, biol more
Getting the Full Picture: Predicting the Aggregation Propensity of mAbs
Getting the full picture: predicting the aggregation propensity of mabs using chemical and thermal denaturation on a single, fully automated platform more
Promotion of Aggregation as a Means of Assessing the Stability of Antibody Molecules
The efficiency of antibody molecules is dependent on their stability. We introduce an assay setup where stability of antibodies is measured. Shaking stress is initiated by the FLUOstar Omega microplate reader and aggregation propensity of antibody ca more
Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications
Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diag more
Agrisera Western Blot recommendations, troubleshooting and protocol
Each antibody-antigen interaction has unique characteristics. A protocol giving good results for one antibody-antigen pair might found to be unsatisfactory for a second antibody even on the same sample. The interaction of antisera with protein epitop more
Characterizing Biotherapeutics with HPLC
As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmace more
Long-term stability at 4 °C. Industrial stabilizer solutions are now affordable for any laboratory. Even moist storage is possible, but with shorter shelf life more
ReadyTector is the all-in-one detection solution for Western blotting. ReadyTector enables a fast one step immunodetection without background more
Mitogenic action of hypoxia upon cutaneous neuroepithelial cells in developing zebrafish
Abstract In zebrafish, cutaneous neuroepithelial cells (NECs) contain serotonin (5‐HT) and are believed to initiate physiological and behavioral responses to hypoxia during embryonic and early larval development, when mature gills and O2 chemoreceptors are not yet present. The number of skin NEC more
Weaponized antibodies use new tricks to fight cancer
Weaponized antibodies use new tricks to fight cancer Nature 540, 7631 (2016). http://www.nature.com/doifinder/10.1038/540019a Author: Heidi Ledford Next generation of Trojan-horse drugs designed to minimize damage to healthy cells. more
Modulation of Immune Checkpoints and Graft-versus-Leukemia in Allogeneic Transplants by Antagoni ...
The goal of allogeneic bone marrow transplantation (allo-BMT) is elimination of leukemia cells through the graft-versus-leukemia (GvL) activity of donor cells, while limiting graft-versus-host disease (GvHD). Immune checkpoint pathways regulate GvL and GvHD activities, but blocking antibodies or gen more
Nitric oxide synthase during early embryonic development in silkworm Bombyx mori: Gene expressio ...
To elucidate the mechanism for embryonic diapause or the breakdown of diapause in Bombyx mori, we biochemically analyzed nitric oxide synthase (NOS) during the embryogenesis of B. mori. The gene expression and enzyme activity of B. mori NOS (BmNOS) were examined in diapause, non‐diapause, and HCl‐ more
In vivo amelioration of endogenous antitumor autoantibodies via low-dose P4N through the LTA4H/a ...
Cancer progression is associated with the development of antitumor autoantibodies in patients’ sera. Although passive treatment with antitumor antibodies has exhibited remarkable therapeutic efficacy, inhibitory effects on tumor progression by endogenous antitumor autoantibodies (EAAs) have been lim more