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ANTIBODIES

Antibodies

Find antibodies by searching for a name or antigen and narrow down your results by defining parameters like reactivity, application, conjugate etc.

News about antibodies
  • First cancer immunotherapy for dogs developed

    Nearly every second dog develops cancer from the age of ten years onward. A few therapies derived from human medicine are available for dogs. A very successful form of therapy by which antibodies inhibit tumor growth has not been available for animals so far. Scientists at the inter-university Messe more

  • Antitope and Synthon announce collaboration

    Antitope Limited, an Abzena company, announced that it will collaborate with Synthon Biopharmaceuticals BV, to assess the potential immunogenicity of candidate antibodies for Synthon’s ADC programmes. Antitope will use its EpiScreen™ technology, a highly accurate and sensitive ex vivo human T cell a more

  • GlycoVaxyn initiates Phase I clinical trial for vaccine against Extra-intestinal pathogenic Esch ...

    GlycoVaxyn AG announced the initiation of a Phase 1 clinical trial of a candidate vaccine to prevent infections caused by Extra-intestinal Pathogenic Escherichia coli (ExPEC), such as urinary tract infections (UTIs). The investigational vaccine is being co-developed by GlycoVaxyn AG and Janssen Phar more

  • A mini-antibody with broad antiviral activity chews up viral DNA and RNA

    Antibodies and their derivatives can protect plants and animals - —including humans - —against viruses. Members of this class of drugs are usually highly specific against components of a particular virus, and mutations in the virus that change these components can make them ineffective. An article i more

  • Merck Serono and Mersana to Develop Next-Generation Antibody-Drug Conjugates

    Merck Serono and Mersana Therapeutics, Inc., Cambridge, Mass., U.S., announced an agreement to collaboratively develop next-generation antibody-drug conjugates (ADCs). ADCs are composed of an antibody linked to cytotoxic drugs, whereby the antibody part specifically targets and delivers the cytotoxi more

White paper on antibodies
  • Promotion of Aggregation as a Means of Assessing the Stability of Antibody Molecules

    The efficiency of antibody molecules is dependent on their stability. We introduce an assay setup where stability of antibodies is measured. Shaking stress is initiated by the FLUOstar Omega microplate reader and aggregation propensity of antibody candidates is measured in 96-well format more

  • Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications

    Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diagnostics more

  • Agrisera Western Blot recommendations, troubleshooting and protocol

    Each antibody-antigen interaction has unique characteristics. A protocol giving good results for one antibody-antigen pair might found to be unsatisfactory for a second antibody even on the same sample. The interaction of antisera with protein epitopes in Western blot dependens upon a number of factors, all contributing to the final signal/noise ratio. Knowledge and control of those factors allows for modifications and optimization of the procedure. Polyclonal antibodies (serum or IgY-fractions from egg yolk) usually contain a number of different antibodies interacting independently with different epitopes on the target used for immunization. This number is limited for peptide-antigens but if recombinant or native proteins have been used for immunization the signal obtained has to be regarded as cumulative (=caused by several different types of antibodies present in the serum/IgY used) more

  • Characterizing Biotherapeutics with HPLC

    As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmaceutical to approval at the regulatory agencies. The introduction of the first so-called biosimilars in Europe further increased the demand for highly efficient analysis methods. The continuous development of new stationary phases for the common modes of biochromatography, such as size exclusion, ion exchange and hydrophilic interaction chromatography support biochemists in increasing lab productivity and establishing high-throughput HPLC analysis not only for small molecules but also for large biopolymers more

  • Functional Analysis of Side Effects of Transfection Reagents in the Context of Bax-induced Apoptosis

    FuGENE® HD Transfection Reagent is well-suited for studying the impact of apoptosis-inducing proteins such as bax. Transfection with FuGENE® HD Transfection Reagent produced only minimal cytotoxic side effects while maintaining a high transfection efficiency. In contrast, cytotoxicity, and off-target effects of the other commercially available transfection reagents tested made it impossible to distinguish the impact of the bax protein from the impact of the transfection reagent itself more

Products for antibodies

The all-in-one Solution for Western blotting

ReadyTector® is the all-in-one detection solution for Western blotting. ReadyTector® enables a fast one step immunodetection without background more

Your antibodies will be happy about it!

Long-term stability at 4°C without inconvenient freezing and thawing? Industrial stabilizer solutions are now affordable for any laboratory more

Protection for antibodies and antigens coated on plates!

Long-term stability at 4°C. Industrial stabilizer solutions are now affordable for any laboratory. Even moist storage is possible, but with shorter shelf life. more

Publications on antibodies
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