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Scientists at the University of Zurich have developed an innovative neural cell culture model, shedding light on the intricate mechanisms underlying neurodegeneration. Their research pinpointed a misbehaving protein as a promising therapeutic target in the treatment of amyotrophic lateral sclerosis more
In neuromuscular diseases, the interaction between neurons and muscle cells is disrupted. Researchers led by Mina Gouti are now able to simulate this in 2D in a culture dish. The approach is well suited for high-throughput screening in drug research, they write in Nature Communications. Around 800 more
Motor neurons in healthy individuals send signals to the skeletal muscles. ALS, however, is currently an incurable, neurodegenerative disease in which motor neurons are severely damaged and can therefore no longer transmit these signals. An interdisciplinary team at HZDR has proven in cell experimen more
Amyotrophic lateral sclerosis Amyotrophic lateral sclerosis (ALS, sometimes called Lou Gehrig 's Disease, or Maladie de Charcot ) is a progressive, usually fatal, neurodegenerative disease caused by the degeneration of motor neurons , the nerve ... more
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