Topic amyotrophic lateral sclerosis

News amyotrophic lateral sclerosis

• BGU researchers make scientific breakthrough in the fight against neurodegenerative diseases

  A patented breakthrough treatment for neurodegenerative diseases has secured over $1 million. Prof. Esther Priel of Ben-Gurion University and her colleagues Prof. Aviv Gazit (formerly of Hebrew University) and Prof. Shimon Slavin (also formerly of Hebrew University and now director of the Internatio more

• Trophos announces results of phase III study of olesoxime in Amyotrophic Lateral Sclerosis

  Trophos SA announced the results from the phase III study of Trophos’ lead compound, olesoxime, in 512 patients with ALS. Olesoxime did not demonstrate a significant increase in survival versus placebo in patients receiving riluzole (Rilutek(R)). A trend was seen on patients’ function as measured by more

• An unexpected player in a cancer defense system

  Researchers of the Swedish medical university Karolinska Institutet and the University of Cologne, Germany, have identified a new protein involved in a defense mechanism against cancer. The VCP/p97 complex is best known for its role in protein destruction and is involved in a type of familial dement more

Publications amyotrophic lateral sclerosis

• Expression of hepatocyte growth factor in the skin of amyotrophic lateral sclerosis

  Nomura M, Oketa Y, Yasui K, Ishikawa H, Ono S. Expression of hepatocyte growth factor in the skin of amyotrophic lateral sclerosis. 
Acta Neurol Scand: 2012: 125: 389–397. 
© 2011 John Wiley & Sons A/S. Objectives –  Hepatocyte growth factor (HGF) is one of the most potent survival‐promoting fa more

• Effect of mitochondrial transcription factor a overexpression on motor neurons in amyotrophic lateral sclerosis model mice

  Abstract Increasing evidence indicates that oxidative stress is an important mechanism underlying motor neuron (MN) degeneration in amyotrophic lateral sclerosis (ALS). Mitochondrial DNA (mtDNA) is highly susceptible to oxidative damage and has little potential for repair, although mitochondrial more

• NIPA1 polyalanine repeat expansions are associated with amyotrophic lateral sclerosis

  Mutations in NIPA1 cause Hereditary Spastic Paraplegia type 6, a neurodegenerative disease characterized by an (upper) motor neuron phenotype. Deletions of NIPA1 have been associated with a higher susceptibility to amyotrophic lateral sclerosis (ALS). The exact role of genetic variation in NIPA1 in more

Market studies amyotrophic lateral sclerosis

• Amyotrophic Lateral Sclerosis Global Clinical Trials Review, H1, 2012

  Introduction GlobalData's clinical trial report, “Amyotrophic Lateral Sclerosis Global Clinical Trials Review, H1, 2012" provides data on the Amyotrophic Lateral Sclerosis clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Amyotrophic La more

• Orphan Diseases Therapeutics in CNS to 2017 - Novel Agents such as AMR101 and ACR16 to Provide Treatment Options and Boost the Huntington’s Disease Segment

  GBI Research, the leading business intelligence provider, has released its latest research “Orphan Diseases Therapeutics in CNS to 2017 - Novel Agents such as AMR101 and ACR16 to Provide Treatment Options and Boost the Huntington’s Disease Segment”, which provides insights into the CNS orphan diseas more

• Endpoints-Clinical Trials in Orphan Diseases - Highest Number of Terminated Trials Focused on Mulitiple Myeloma

  GBI Research, the leading business intelligence provider, has released its latest research report, “Endpoints-Clinical Trials in Orphan Diseases - Highest Number of Terminated Trials Focused on Mulitiple Myeloma” providing an insight into different endpoints that are used in orphan disease clinical more

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