Acid

News Acid

• Vitamin C does not lower uric acid levels in gout patients

  Despite previous studies touting its benefit in moderating gout risk, new research reveals that vitamin C, also known ascorbic acid, does not reduce uric acid (urate) levels to a clinically significant degree in patients with established gout. Vitamin C supplementation, alone or in combination with more

• Plate reader for drug discovery
  

  The trend towards automated high content assays, particularly for systems biology and drug discovery, has stimulated the development of automated fluorescence microscopy systems to image sample arrays. Today’s commercially available high content analysis (HCA) instruments predominantly employ fluore more

• AiCuris Gained Bio.NRW Research Promotion

  AiCuris GmbH & Co. KG has been awarded a three-year research grant together with the Universities of Bochum, Düsseldorf and Bonn as well as the company Squarix (Marl). This grant is a part of the research promotion program “Bio.NRW” by the Ministry of Innovation, Science and Research of North Rhine- more

White papers Acid

• MagNA Pure 96 Cellular RNA Kits: RNA Isolation on the Fast Lane
  

  Advancements in high-throughput gene expression analysis have set a new demand for automated isolation of cellular RNA from high sample numbers in parallel. The availability of the innovative MagNA Pure 96 System together with dedicated kits, protocols, and consumables sets a new standard in truly walkaway high-throughput automated nucleic acid sample preparation more

• Real-Time PCR Quantification of Plant miRNAs Using Universal ProbeLibrary Technology
  

  MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (18-25 nt in length) that are processed from larger hairpin precursors. Both plant and animal genomes encode miRNAs, and to date, there are over 4000 mature miRNA transcripts annotated. Although miRNAs represent a relatively abundant class of transcripts, their expression levels vary greatly among species and tissues. Less abundant miRNAs routinely fail detection using technologies such as cloning, northern hybridization and microarray analysis. Here, we present a real-time quantification method for accurate, sensitive, and economical detection of plant miRNAs based upon the stem-loop RT primer approach using an miRNA-specific primer coupled with a stem-loop specific Universal ProbeLibrary (UPL) probe. This approach represents a highly specific, sensitive, and easy-to-apply system to detect miRNAs. more

• Molecular diagnostic test applied to ascitic fluid
  

  Spontaneous bacterial peritonitis (SBP) is a common and life-threatening complication of patients with ascites and cirrhosis of the liver. The mortality accounts for up to 30-50% and such patients die within several hours after infection. An early diagnosis and subsequent antibiotic therapy are prerequisites for the survival of the patients. The clinical standard for a diagnosis of SBP is the increased number of polymorphic neutrophilic cells in the ascites (> 250/l), independent of the results obtained with ascites cultures. An increased cell count is not detectable in all patients. Positive ascites cultures are typically found in 40-90% of all SBP cases. more

Publications Acid

• Occurrence of free deaminoneuraminic acid (KDN)-containing complex-type N-glycans in human prostate cancers

  We previously reported on the accumulation of a substantial amount of free N-acetylneuraminic acid (Neu5Ac)-containing complex-type N-glycans in human pancreatic cancer cells (Yabu M, Korekane H, Takahashi H, Ohigashi H, Ishikawa O, Miyamoto Y. 2013. Accumulation of free Neu5Ac-containing complex-t more

• GPAT2, a mitochondrial outer membrane protein, in piRNA biogenesis in germline stem cells [ARTICLES]

  piRNA (PIWI-interacting RNA) is a germ cell–specific small RNA in which biogenesis PIWI (P-element wimpy testis) family proteins play crucial roles. MILI (mouse Piwi-like), one of the three mouse PIWI family members, is indispensable for piRNA production, DNA methylation of retrotransposons presuma more

• Hyaluronan nanocapsules as a new vehicle for intracellular drug delivery

  Publication date: Available online 15 May 2013 Source:European Journal of Pharmaceutical Sciences Author(s): Felipe A. Oyarzun-Ampuero , Gustavo R. Rivera-Rodríguez , Maria J. Alonso , Dolores Torres Here we report the development of new drug nanocarriers -named hyaluronan nanocapsules- fo more

Market studies Acid

• Acid Indigestion / Heartburn/ Pyrosis Global Clinical Trials Review, H1, 2012

  Introduction GlobalData's clinical trial report, “Acid Indigestion / Heartburn/ Pyrosis Global Clinical Trials Review, H1, 2012" provides data on the Acid Indigestion / Heartburn/ Pyrosis clinical trial scenario. This report provides elemental information and data relating to the clinical trials o more

• Acid Sphingomyelinase Deficiency (Niemann-Pick Disease) – Pipeline Review, H1 2012

  Introduction Global Markets Direct’s, 'Acid Sphingomyelinase Deficiency (Niemann-Pick Disease) - Pipeline Review, H1 2012', provides an overview of the Acid Sphingomyelinase Deficiency (Niemann-Pick Disease) therapeutic pipeline. This report provides information on the therapeutic development for more

• Women’s Health Therapeutics Market to 2017 - High Unmet Need will Drive Uptake of Novel Drugs Such as Prolia and Odanocantib in the Menopause and Osteoporosis Market

  GBI Research, a leading business intelligence provider, has released its latest research “Women’s Health Therapeutics Market to 2017 - High Unmet Need will Drive Uptake of Novel Drugs Such as Prolia and Odanocantib in the Menopause and Osteoporosis Market”. The report provides in-depth analysis of t more

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