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1.386 Aktuelle Fachpublikationen zum Thema Malaria

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Dark nights, bright stars

15.06.2018 | Jon Cohen, Science , 2018

At a time when HIV epidemics in Western Europe are shrinking, Russia's is growing by about 10% a year. Russia, in fact, between 2010 and 2015 accounted for more than 80% of all the new infections in Eastern Europe and Central Asia. Not only has the country turned away assistance from The Global ...

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Kinetics of antibody responses to PfRH5-complex antigens in Ghanaian children with Plasmodium falciparum malaria

08.06.2018 | Frederica D. Partey; Filip C. Castberg; Edem W. Sarbah; Sarah E. Silk; Gordon A. Awandare; Simon J. Draper; Nicholas ..., PLoS ONE, 2018

by Frederica D. Partey, Filip C. Castberg, Edem W. Sarbah, Sarah E. Silk, Gordon A. Awandare, Simon J. Draper, Nicholas Opoku, Margaret Kweku, Michael F. Ofori, Lars Hviid, Lea Barfod Plasmodium falciparum PfRH5 protein binds Ripr, CyRPA and Pf113 to form a complex that is essential for ...

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Associated patterns of insecticide resistance in field populations of malaria vectors across Africa [Applied Biological Sciences]

05.06.2018 | Penelope A. Hancock; Antoinette Wiebe; Katherine A. Gleave; Samir Bhatt; Ewan Cameron; Anna Trett; David Weetman; Da ..., Proceedings of the National Academy of Sciences current issue, 2018

Malaria control programs rely on chemical insecticides to target mosquito vectors and are potentially threatened by the emergence of insecticide resistance in African vector populations. Insecticide resistance management initiatives require comprehensive quantification of resistance in field ...

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Volatile biomarkers of symptomatic and asymptomatic malaria infection in humans [Medical Sciences]

29.05.2018 | Consuelo M. De Moraes; Caroline Wanjiku; Nina M. Stanczyk; Hannier Pulido; James W. Sims; Heike S. Betz; Andrew F. R ..., Proceedings of the National Academy of Sciences current issue, 2018

Malaria elimination efforts are hindered by the prevalence of asymptomatic infections, which frequently go undetected and untreated. Consequently, there is a pressing need for improved diagnostic screening methods. Based on extensive collections of skin odors from human populations in Kenya, we ...

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Reducing resistance allele formation in CRISPR gene drive [Genetics]

22.05.2018 | Jackson Champer; Jingxian Liu; Suh Yeon Oh; Riona Reeves; Anisha Luthra; Nathan Oakes; Andrew G. Clark; Philipp W. M ..., Proceedings of the National Academy of Sciences current issue, 2018

A functioning gene drive mechanism could fundamentally change our strategies for the control of vector-borne diseases, such as malaria, dengue, and Zika. CRISPR homing gene drive promises such a mechanism, which could be used to rapidly spread genetic modifications among the mosquitoes that ...

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Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection

18.05.2018 | Dora Posfai; Kayla Sylvester; Anupama Reddy; Jack G. Ganley; Johannes Wirth; Quinlan E. Cullen; Tushar Dave; Nobutak ..., PLoS Pathogens, 2018

by Dora Posfai, Kayla Sylvester, Anupama Reddy, Jack G. Ganley, Johannes Wirth, Quinlan E. Cullen, Tushar Dave, Nobutaka Kato, Sandeep S. Dave, Emily R. Derbyshire Within the liver a single Plasmodium parasite transforms into thousands of blood-infective forms to cause malaria. Here, we use ...

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Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection

18.05.2018 | Dora Posfai; Kayla Sylvester; Anupama Reddy; Jack G. Ganley; Johannes Wirth; Quinlan E. Cullen; Tushar Dave; Nobutak ..., PLoS Pathogens, 2018

by Dora Posfai, Kayla Sylvester, Anupama Reddy, Jack G. Ganley, Johannes Wirth, Quinlan E. Cullen, Tushar Dave, Nobutaka Kato, Sandeep S. Dave, Emily R. Derbyshire Within the liver a single Plasmodium parasite transforms into thousands of blood-infective forms to cause malaria. Here, we use ...

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Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite

16.05.2018 | Christine Lehmann; Michele Ser Ying Tan; Laura E. de Vries; Ilaria Russo; Mateo Isidrio Sanchez; Daniel E. Goldberg; ..., PLoS Pathogens, 2018

by Christine Lehmann, Michele Ser Ying Tan, Laura E. de Vries, Ilaria Russo, Mateo Isidrio Sanchez, Daniel E. Goldberg, Edgar Deu Parasite egress from infected erythrocytes and invasion of new red blood cells are essential processes for the exponential asexual replication of the malaria ...

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Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite

16.05.2018 | Christine Lehmann; Michele Ser Ying Tan; Laura E. de Vries; Ilaria Russo; Mateo Isidrio Sanchez; Daniel E. Goldberg; ..., PLoS Pathogens, 2018

by Christine Lehmann, Michele Ser Ying Tan, Laura E. de Vries, Ilaria Russo, Mateo Isidrio Sanchez, Daniel E. Goldberg, Edgar Deu Parasite egress from infected erythrocytes and invasion of new red blood cells are essential processes for the exponential asexual replication of the malaria ...

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Modeling the impact of Plasmodium falciparum sexual stage immunity on the composition and dynamics of the human infectious reservoir for malaria in natural settings

09.05.2018 | André Lin Ouédraogo; Philip A. Eckhoff; Adrian J. F. Luty; Will Roeffen; Robert W. Sauerwein; Teun Bousema; Edward A ..., PLoS Pathogens, 2018

by André Lin Ouédraogo, Philip A. Eckhoff, Adrian J. F. Luty, Will Roeffen, Robert W. Sauerwein, Teun Bousema, Edward A. Wenger Malaria transmission remains high in Sub-Saharan Africa despite large-scale implementation of malaria control interventions. A comprehensive understanding of the ...

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