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SMN deficiency disrupts gastrointestinal and enteric nervous system function in mice

01.07.2015 | Sara E. Gombash; Christopher J. Cowley; Julie A. Fitzgerald; Chitra C. Iyer; David Fried; Vicki L. McGovern; Kent C. ..., Human Molecular Genetics, 2015

The 2007 Consensus Statement for Standard of Care in Spinal Muscular Atrophy (SMA) notes that patients suffer from gastroesophageal reflux, constipation and delayed gastric emptying. We used two mouse models of SMA to determine whether functional GI complications are a direct consequence of or ...


Viruses, Vol. 7, Pages 3483-3499: Pan-Genome Analysis of Brazilian Lineage A Amoebal Mimiviruses

26.06.2015 | Assis, Felipe L.; Bajrai, Leena ; Abrahao, Jonatas S.; Kroon, Erna G.; Dornas, Fabio P.; Andrade, Kétyllen R.; Borat ..., Viruses, 2015

Since the recent discovery of Samba virus, the first representative of the family Mimiviridae from Brazil, prospecting for mimiviruses has been conducted in different environmental conditions in Brazil. Recently, we isolated using Acanthamoeba sp. three new mimiviruses, all of lineage A of ...


Energies, Vol. 8, Pages 6350-6364: Bio-Refining of Carbohydrate-Rich Food Waste for Biofuels

25.06.2015 | Hao, Hoang-Tuong Nguyen; Karthikeyan, Obulisamy Parthiba; Heimann, Kirsten, Energies, 2015

The global dependence on finite fossil fuel-derived energy is of serious concern given the predicted population increase. Over the past decades, bio-refining of woody biomass has received much attention, but data on food waste refining are sorely lacking, despite annual and global deposition of ...


Camelina Oil as a Source of Polyunsaturated Fatty Acids for the Production of Human Milk Fat Substitutes Catalyzed by a Heterologous Rhizopus oryzae Lipase

24.06.2015 | Ana Rita Faustino, Natália M. Osório, Carla Tecelão, Albert Canet, Francisco Valero, Suzana Ferreira‐Dias, European Journal of Lipid Science and Technology, 2015

This study aims to produce human milk fat substitutes (HMFS) rich in polyunsaturated fatty acids (PUFA), mainly the essential omega‐3 linolenic acid, by acidolysis reaction between tripalmitin (PPP) and free fatty acids (FFA) from camelina oil, in stirred batch reactor and solvent‐free media. ...


The Role of miR156/SPLs Modules in Arabidopsis Lateral Root Development

20.06.2015 | Niu Yu, Qi‐Wen Niu, Kian‐Hong Ng, Nam‐Hai Chua, The Plant Journal, 2015

Summary miR156 is an evolutionarily highly conserved miRNA in plants that defines an age‐dependent flowering pathway. The investigations thus far have largely, if not exclusively, confined to plant aerial organs. Root branching architecture is a major determinant of water and nutrients uptake ...


Reclamation of Water Polluted with Flubendiamide Residues by Photocatalytic Treatment with Semiconductor Oxides

18.06.2015 | José Fenoll, Nuria Vela, Isabel Garrido, Ginés Navarro, Gabriel Pérez‐Lucas, Simón Navarro, Photochemistry and Photobiology, 2015

Abstract The photodegradation of flubendiamide (benzenedicarboxamide insecticide), a relatively new insecticide was investigated in aqueous suspensions of binary (ZnO and TiO2) and ternary (Zn2TiO4 and ZnTiO3) oxides under artificial light (300‐460 nm) irradiation. Photocatalytic experiments ...


Schisandrin C Ameliorates Learning and Memory Deficits by Aβ1–42‐induced Oxidative Stress and Neurotoxicity in Mice

15.06.2015 | Xin Mao, Zhengzheng Liao, Lin Guo, Xuan Xu, Bo Wu, Mengjie Xu, Xu Zhao, Kaishun Bi, Ying Jia, Phytotherapy Research, 2015

Schisandrin C (SCH‐C) is a main and typical antioxidative lignan isolated from the fruits of Schisandra chinensis (Trucz.) Baill (a widely used traditional Chinese medicine). The present study aimed to characterize the effect of SCH‐C on memory impairment and further research on pathological ...


Improved Sterilization of Sensitive Biomaterials with Supercritical Carbon Dioxide at Low Temperature

12.06.2015 | Anne Bernhardt et al., PLoS ONE, 2015

by Anne Bernhardt, Markus Wehrl, Birgit Paul, Thomas Hochmuth, Matthias Schumacher, Kathleen Schütz, Michael Gelinsky The development of bio-resorbable implant materials is rapidly going on. Sterilization of those materials is inevitable to assure the hygienic requirements for critical medical ...


Maize Genotypes Differing in Salt Resistance Vary in Jasmonic Acid Accumulation During the First Phase of Salt Stress

03.06.2015 | A. N. Shahzad, B. Pitann, H. Ali, M. F. Qayyum, A. Fatima, H. F. Bakhat, Journal of Agronomy and Crop Science, 2015

Abstract Plant hormones are considered to play an important role in plant adaptation to drought and salt stress. The objective of the study was to investigate the changes in endogenous jasmonic acid (JA) in relation to differences in the salt resistance of maize genotypes. Two maize genotypes ...


Inner Mongolian steppe arbuscular mycorrhizal fungal communities respond more strongly to water availability than to nitrogen fertilization

02.06.2015 | Xiaoliang Li, Tingyao Zhu, Fei Peng, Qing Chen, Shan Lin, Peter Christie, Junling Zhang, Environmental Microbiology, 2015

Abstract Plant community productivity and species composition are primarily constrained by water followed by nitrogen availability in the degraded semiarid grasslands of Inner Mongolia. However, there is a lack of knowledge on how long‐term N addition and water availability interact to ...


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