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784 Aktuelle Fachpublikationen zum Thema Addition

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Assessment of oxidative damage to DNA, transcriptional expression of key genes, lipid peroxidation and histopathological changes in carp Cyprinus carpio L. following exposure to chronic hypoxic and subsequent recovery in normoxic conditions

01.01.2015 | Sanaa A. Mustafa; Sahar S. Karieb; Simon J. Davies; Awadhesh N. Jha, Mutagenesis, 2015

In fish, a complex set of mechanisms deal with environmental stresses including hypoxia. In order to probe the hypothesis that hypoxia-induced stress could be manifested in varieties of pathways, a model species, mirror carp (Cyprinus carpio), were chronically exposed to hypoxic condition ...

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G protein-coupled receptors: bridging the gap from the extracellular signals to the Hippo pathway

01.01.2015 | Xin Zhou; Zhen Wang; Wei Huang; Qun-Ying Lei, Acta Biochimica et Biophysica Sinica, 2015

The Hippo pathway is crucial in organ size control, whereas its dysregulation contributes to organ degeneration or tumorigenesis. The kinase cascade of MST1/2 and LATS1/2 and the coupling transcription co-activators YAP/TAZ represent the core components of the Hippo pathway. Extensive studies ...

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Novel co‐enrichment method for isolation of magnetotactic bacteria

28.12.2014 | Ajay M. Sorty, Nasir R. Shaikh, Journal of Basic Microbiology, 2014

A novel co‐enrichment technique was designed for enrichment of magnetotactic bacteria from soil, water, and sediments. Delayed addition of iron uptake inducer and the iron source proved amenable to induce magnetosome synthesis by MTB followed by their separation from consortium using magnetic ...

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Ginsenoside Re protects methamphetamine‐induced mitochondrial burdens and proapoptosis via genetic inhibition of protein kinase C δ in human neuroblastoma dopaminergic SH‐SY5Y cell lines

19.12.2014 | Yunsung Nam, Myung Bok Wie, Eun‐Joo Shin, Thuy‐Ty Lan Nguyen, Seung‐Yeol Nah, Sung Kwon Ko, Ji Hoon Jeong, Choon‐Gon ..., Journal of Applied Toxicology, 2014

ABSTRACT Recently, we have demonstrated that ginsenoside Re protects methamphetamine (MA)‐induced dopaminergic toxicity in mice via genetic inhibition of PKCδ and attenuation of mitochondrial stress. In addition, we have reported that induction of mitochondrial glutathione peroxidase (GPx) is ...

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MicroRNA Profiling in Human Colon Cancer Cells during 5-Fluorouracil-Induced Autophagy

19.12.2014 | Ni Hou et al., PLoS ONE, 2014

by Ni Hou, Jia Han, Jie Li, Yingxun Liu, Yannan Qin, Lei Ni, Tusheng Song, Chen Huang Autophagy modulation is now recognized as a potential therapeutic approach for cancer (including colorectal cancer), yet the molecular mechanisms regulating autophagy in response to cellular stress are still ...

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Arabidopsis ROOT HAIR DEFECTIVE3 is involved in nitrogen starvation‐induced anthocyanin accumulation

10.12.2014 | Jing Wang, Yan Wang, Ju Yang, Chunli Ma, Ying Zhang, Ting Ge, Zhi Qi, Yan Kang, Journal of Integrative Plant Biology, 2014

Abstract Anthocyanin accumulation is a common phenomenon seen in plants under environmental stress. In this study, we identified a new allele of ROOT HAIR DEFECTIVE3 (RHD3) showing an anthocyanin overaccumulation phenotype under nitrogen starvation conditions. It is known that ethylene ...

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A new point mutation in the iron‐sulphur subunit of succinate dehydrogenase confers resistance to boscalid in Sclerotinia sclerotiorum

02.12.2014 | Yong Wang, Yabing Duan, Jianxin Wang, Mingguo Zhou, Molecular Plant Pathology, 2014

Summary Research has established that mutations in highly conserved amino acids of the succinate dehydrogenase (SDH) complex in various fungi confers SDHI resistance. For Sclerotinia sclerotiorum (Lib.) de Bary, a necrotrophic fungus with a broad host range and a worldwide distribution, ...

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Seed biopriming with drought tolerant isolates of Trichoderma harzianum promote growth and drought tolerance in Triticum aestivum

02.12.2014 | N. Shukla, R.P. Awasthi, L. Rawat, J. Kumar, Annals of Applied Biology, 2014

Abstract Green house study was aimed to investigate the effect of seed biopriming with drought tolerant isolates of Trichoderma harzianum, viz. Th 56, 69, 75, 82 and 89 on growth of wheat under drought stress and to explore the mechanism underlying plant water stress resilience in response to ...

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Using Improved Serial Blood Sampling Method of Mice to Study Pharmacokinetics and Drug–Drug Interaction

01.12.2014 | Ayahisa Watanabe, Ryosuke Watari, Keiko Ogawa, Ryosuke Shimizu, Yukari Tanaka, Nozomi Takai, Ken‐Ichi Nezasa, Yoshit ..., Journal of Pharmaceutical Sciences, 2014

In pharmacokinetic evaluation of mice, using serial sampling methods rather than a terminal blood sampling method could reduce the number of animals needed and lead to more reliable data by excluding individual differences. In addition, using serial sampling methods can be valuable for ...

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Emission of methane, carbon monoxide, carbon dioxide and short‐chain hydrocarbons from vegetation foliage under ultraviolet irradiation

01.12.2014 | WESLEY T. FRASER, EMANUEL BLEI, STEPHEN C. FRY, MARK F. NEWMAN, DAVID S. REAY, KEITH A. SMITH, ANDY R. MCLEOD, Plant, Cell & Environment, 2014

Abstract The original report that plants emit methane (CH4) under aerobic conditions caused much debate and controversy. Critics questioned experimental techniques, possible mechanisms for CH4 production and the nature of estimating global emissions. Several studies have now confirmed that ...

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