Meine Merkliste  

817 Aktuelle Fachpublikationen zum Thema Addition

mit folgenden Suchkriterien:

In Vitro Coinfection and Replication of Classical Swine Fever Virus and Porcine Circovirus Type 2 in PK15 Cells

02.10.2015 | Niu Zhou et al., PLoS ONE, 2015

by Niu Zhou, Gang Xing, Jianwei Zhou, Yulan Jin, Cuiqin Liang, Jinyan Gu, Boli Hu, Min Liao, Qin Wang, Jiyong Zhou Increasing clinical lines of evidence have shown the coinfection/superinfection of porcine circovirus type 2 (PCV2) and classical swine fever virus (CSFV). Here, we investigated ...


Marine Drugs, Vol. 13, Pages 6259-6273: Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells

02.10.2015 | Chen, Junxiong ; Wang, Chenliang ; Lan, Wenjian ; Huang, Chunying ; Lin, Mengmeng ; Wang, Zhongyang ; Liang, Wanling ..., Marine Drugs, 2015

The discovery of new bioactive compounds from marine natural sources is very important in pharmacological research. Here we developed a Wnt responsive luciferase reporter assay to screen small molecule inhibitors of cancer associated constitutive Wnt signaling pathway. We identified that ...


Metformin: A Novel but Controversial Drug in Cancer Prevention and Treatment

02.10.2015 | Xinbing Sui; Yinghua Xu; Xian Wang; Weidong Han; Hongming Pan; Mang Xiao, Molecular Pharmaceutics, 2015

Metformin, a biguanide derivative that is widely used for treating type 2 diabetes mellitus, has recently been shown to exert potential anticancer effects. Many retrospective data and laboratory studies suggest the idea that metformin has antineoplastic activity, but some other studies reach ...


Down-regulation of lipocalin 2 suppresses the growth of human lung adenocarcinoma through oxidative stress involving Nrf2/HO-1 signaling

01.10.2015 | Baoquan Song; Hairui Zhang; Lei Jiang; Ying Chi; Jianjian Tian; Wenjing Du; Bentong Yu; Zhongchao Han, Acta Biochimica et Biophysica Sinica, 2015

Lipocalin 2 (LCN2), a multifunctional secretory protein known as neutrophil gelatinase-associated lipocalin (NGAL), is expressed in a variety of cancers. However, little is known about the biological functions of NGAL in the development of lung adenocarcinoma. In the present study, we primarily ...


The Stress Kinase p38{alpha} as a Target for Cancer Therapy

01.10.2015 | Ana Igea; Angel R. Nebreda, Cancer Research, 2015

p38α is a ubiquitous protein kinase strongly activated by stress signals, inflammatory cytokines, and many other stimuli, which has been implicated in the modulation of multiple cellular processes. There is good evidence in the literature that p38α plays an important tumor-suppressor role by ...


Marine Drugs, Vol. 13, Pages 6152-6209: Bioactive Compounds Isolated from Microalgae in Chronic Inflammation and Cancer

30.09.2015 | Talero, Elena ; García-Mauriño, Sofía ; Ávila-Román, Javier ; Rodríguez-Luna, Azahara ; Alcaide, Antonio ; Motilva, ..., Marine Drugs, 2015

The risk of onset of cancer is influenced by poorly controlled chronic inflammatory processes. Inflammatory diseases related to cancer development include inflammatory bowel disease, which can lead to colon cancer, or actinic keratosis, associated with chronic exposure to ultraviolet light, which ...


Design, synthesis and biological evaluation of novel cholesteryl peptides with anti‐cancer and multidrug resistance‐reversing activities

22.09.2015 | Xin Deng, Qianqian Qiu, Xuekun Wang, Wenlong Huang, Hai Qian, Chemical Biology & Drug Design, 2015

Abstract Antimicrobial peptides have been suggested as promising chemotherapeutics for cancer therapy due to their efficient anti‐tumor activity and lower toxicity to benign cells. In previous study, we find the peptide B1 presents specific cytotoxicity to cancer cells. As hydrophobicity plays ...


Long noncoding RNA CCAT2 promotes breast tumor growth by regulating the Wnt signaling pathway

21.09.2015 | OncoTargets and Therapy, 2015

In addition to protein-coding genes, the human genome makes a large amount of noncoding RNAs, including microRNAs and long noncoding RNAs (lncRNAs). Emerging evidence indicates that lncRNAs could have a critical role in the regulation of cellular processes such as cell growth and apoptosis as ...


Bone Marrow Endothelial Progenitor Cell Transplantation After Ischemic Stroke: An Investigation Into Its Possible Mechanism

19.09.2015 | Ying‐Ying Bai, Xin‐Gui Peng, Li‐Shan Wang, Zi‐Hui Li, Yuan‐Cheng Wang, Chun‐Qiang Lu, Jie Ding, Pei‐Cheng Li, Zhen Z ..., CNS Neuroscience & Therapeutics, 2015

Summary Aims We tested the hypothesis that endothelial progenitor cell (EPC)‐mediated functional recovery after stroke may be associated with the endothelial nitric oxide synthase (eNOS)/brain‐derived neurotrophic factor (BDNF) signaling pathway. Methods Mice were infused with either ...


AMP‐activated protein kinase couples 3‐bromopyruvate‐induced energy depletion to apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl‐2 proteins

16.09.2015 | Cagri Bodur, Bahriye Karakas, Ahmet Can Timucin, Tugsan Tezil, Huveyda Basaga, Molecular Carcinogenesis, 2015

Most tumors primarily rely on glycolysis rather than mitochondrial respiration for ATP production. This phenomenon, also known as Warburg effect, renders tumors more sensitive to glycolytic disturbances compared to normal cells. 3‐bromopyruvate is a potent inhibitor of glycolysis that shows ...


Seite 1 von 82
Suche per e-Mail abonnieren

Sie erhalten passend zu Ihrer Suche die neusten Suchergebnisse per E-Mail. Dieser Service ist für Sie kostenlos und kann jederzeit abbestellt werden.

Ihr Bowser ist nicht aktuell. Microsoft Internet Explorer 6.0 unterstützt einige Funktionen auf Chemie.DE nicht.