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1.691 Aktuelle Fachpublikationen zum Thema Addition

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Effect of TAT‐obestatin on proliferation, differentiation, apoptosis and lipolysis in 3T3‐L1 preadipocytes

14.09.2013 | Guangcai Ren, Zuyong He, Peiqing Cong, Jingwei Yu, Yufeng Qin, Yaosheng Chen, Xiaohong Liu, Journal of Peptide Science, 2013

It has been reported that obestatin regulates adipocyte metabolism via receptors on the cell surface. We wondered whether obestatin can interact with intracellular components that activated signalling pathways in adipocytes. Because obestatin (human) only presents one lysine (at position 10), ...


Risk of hepatocellular carcinoma and cancers at other sites among patients diagnosed with chronic hepatitis B virus infection in Sweden

13.09.2013 | Kristina Sundquist, Jan Sundquist, Jianguang Ji, Journal of Medical Virology, 2013

Abstract Hepatitis B virus (HBV) infection is one of most common viral infections worldwide. While chronic HBV infection has been shown consistently to be associated with hepatocellular carcinoma, data on associations with cancers at other sites are limited. In this study a total of 10,197 ...


Piezoelectric properties of aligned collagen membranes

13.09.2013 | D. Denning, M. V. Paukshto, S. Habelitz, B. J. Rodriguez, Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2013

Abstract Electromechanical coupling, a phenomenon present in collagenous materials, may influence cell–extracellular matrix interactions. Here, electromechanical coupling has been investigated via piezoresponse force microscopy in transparent and opaque membranes consisting of helical‐like ...


Molecular farming in tobacco hairy roots by triggering the secretion of a pharmaceutical antibody

12.09.2013 | Suvi T. Häkkinen, Nicole Raven, Maurice Henquet, Marja‐Leena Laukkanen, Tibor Anderlei, Juha‐Pekka Pitkänen, Richard ..., Biotechnology and Bioengineering, 2013

Abstract Recombinant pharmaceutical proteins expressed in hairy root cultures can be secreted into the medium to improve product homogeneity and to facilitate purification, although this may result in significant degradation if the protein is inherently unstable or particularly susceptible to ...


Human papillomavirus infection in women in four regions of Senegal

11.09.2013 | El Hadji Seydou Mbaye, Tarik Gheit, Ahmadou Dem, Sandrine McKay‐Chopin, Ndeye Coumba Toure‐Kane, Souleymane Mboup, M ..., Journal of Medical Virology, 2013

Abstract Cervical cancer is the most frequent cancer among women in Senegal. However, there are few data concerning the human papillomavirus (HPV) types inducing neoplasia and cervical cancers and their prevalence in the general population of Senegal. The aim of this study is to determine the ...


Isolation of cross‐reactive human monoclonal antibodies that prevent binding of human noroviruses to histo‐blood group antigens

11.09.2013 | Kyoko Higo‐Moriguchi, Haruko Shirato, Yuichi Someya, Yoshikazu Kurosawa, Naokazu Takeda, Koki Taniguchi, Journal of Medical Virology, 2013

Abstract In order to identify the repertoire of antibodies generated on natural infection of norovirus (NoV) in humans, and to characterize the human monoclonal antibodies against NoV, three phage‐displayed antibody libraries originating from healthy person(s) were screened using purified ...


Type dependent patterns of human adenovirus persistence in human T‐lymphocyte cell lines

11.09.2013 | Dominik Markel, Elena Lam, Gabriele Harste, Sebastian Darr, Mirja Ramke, Albert Heim, Journal of Medical Virology, 2013

Abstract Disseminated adenovirus infections cause significant mortality in stem cell transplanted patients and are suspected to originate from asymptomatic adenovirus persistence (“latency”) in lymphocytes. The infection of three human T‐lymphocyte lines (Jurkat, PM1, and CEM) with human ...


Utilization of flax fibers for biomedical applications

11.09.2013 | Sophie A. A. X. Michel, Ruben R. M. Vogels, Nicole D. Bouvy, Menno L. W. Knetsch, Nynke M. S. Akker, Marion J. J. Gi ..., Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2013

Abstract Over the past decades, a large number of animal‐derived materials have been introduced for several biomedical applications. Surprisingly, the use of plant‐based materials has lagged behind. To study the feasibility of plant‐derived biomedical materials, we chose flax (Linum ...


Induction of apoptosis in human myeloid leukemia cells by remote exposure of resistive barrier cold plasma

11.09.2013 | Magesh Thiyagarajan, Heather Anderson, Xavier F. Gonzales, Biotechnology and Bioengineering, 2013

Abstract Cold atmospheric plasma (CAP), an ambient temperature ionized gas, is gaining extensive interest as a promising addition to anti‐tumor therapy primarily due to the ability to generate and control delivery of electrons, ions, excited molecules, UV photons, and reactive species such as ...


N‐acetyl‐L‐cysteine enhances fisetin‐induced cytotoxicity via induction of ROS‐independent apoptosis in human colonic cancer cells

09.09.2013 | Ming‐Shun Wu, Gi‐Shih Lien, Shing‐Chuan Shen, Liang‐Yo Yang, Yen‐Chou Chen, Molecular Carcinogenesis, 2013

Abstract Oxidative stress or excessive antioxidant levels‐caused redox imbalance can alter apoptotic responses, and N‐acetyl‐L‐cysteine (NAC) was able to inhibit H2O2‐mediated cell death, but unable to prevent apoptosis induced by other chemicals such as etoposide. We now demonstrate that 10 ...


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