01.06.2013 | Qiong Ke; Li Li; Bing Cai; Chang Liu; Yan Yang; Yong Gao; Weijun Huang; Xiaofeng Yuan; Tao Wang; Qi Zhang; Andrew L. ..., Human Molecular Genetics, 2013

Although somatic cells can be successfully programmed to create pluripotent stem cells by ectopically expressing defined transcriptional factors, reprogramming efficiency is low and the reprogramming mechanism remains unclear. Previous reports have shown that almost all human connexin (CX) ...

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01.06.2013 | Mélisande Blein-Nicolas; Warren Albertin; Benoît Valot; Philippe Marullo; Delphine Sicard; Christophe Giraud; Sylvie ..., Molecular Biology and Evolution, 2013

Saccharomyces cerevisiae and S. uvarum are two domesticated species of the Saccharomyces sensu stricto clade that diverged around 100 Ma after whole-genome duplication. Both have retained many duplicated genes associated with glucose fermentation and are characterized by the ability to ...

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01.06.2013 | Zhang Wang; Martin Wu, Molecular Biology and Evolution, 2013

Large-scale, genome-level molecular phylogenetic analyses present both opportunities and challenges for bacterial evolutionary and ecological studies. We constructed a phylum-level bacterial phylogenetic marker database by surveying all complete bacterial genomes and identifying single-copy ...

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01.06.2013 | Manuel Gil; Marcelo Serrano Zanetti; Stefan Zoller; Maria Anisimova, Molecular Biology and Evolution, 2013

Markov models of codon substitution naturally incorporate the structure of the genetic code and the selection intensity at the protein level, providing a more realistic representation of protein-coding sequences compared with nucleotide or amino acid models. Thus, for protein-coding genes, ...

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01.06.2013 | Masahiko Yabu; Hiroaki Korekane; Koji Hatano; Yasufumi Kaneda; Norio Nonomura; Chihiro Sato; Ken Kitajima; Yasuhide ..., Glycobiology , 2013

We previously reported on the accumulation of a substantial amount of free N-acetylneuraminic acid (Neu5Ac)-containing complex-type N-glycans in human pancreatic cancer cells (Yabu M, Korekane H, Takahashi H, Ohigashi H, Ishikawa O, Miyamoto Y. 2013. Accumulation of free Neu5Ac-containing ...

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20.05.2013 | Author(s): Tamás Vigh , Tímea Horváthová , Attila Balogh , Péter Lajos Sóti , Gábor Drávavölgyi , Zsombor Krist ..., European Journal of Pharmaceutical Science, 2013

Publication date: Available online 14 May 2013 Source:European Journal of Pharmaceutical Sciences Author(s): Tamás Vigh , Tímea Horváthová , Attila Balogh , Péter Lajos Sóti , Gábor Drávavölgyi , Zsombor Kristóf Nagy , György Marosi Fast-release nano- and microfibres of ...

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19.05.2013 | Author(s): Raphael J. Gübeli , Dougal Laird , Martin Ehrbar , Benjamin S. Ritter , Thorsten Steinberg , Pascal ..., Acta Biomaterialia, 2013

Publication date: Available online 16 May 2013 Source:Acta Biomaterialia Author(s): Raphael J. Gübeli , Dougal Laird , Martin Ehrbar , Benjamin S. Ritter , Thorsten Steinberg , Pascal Tomakidi , Wilfried Weber Biohybrid materials combining synthetic polymers with biological ...

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19.05.2013 | Author(s): Peter Cass , Warren Knower , Tracey Hinton , Shuning Shi , Felix Grusche , Mark Tizard , Pathiraja ..., Acta Biomaterialia, 2013

Publication date: Available online 16 May 2013 Source:Acta Biomaterialia Author(s): Peter Cass , Warren Knower , Tracey Hinton , Shuning Shi , Felix Grusche , Mark Tizard , Pathiraja Gunatillake Chain extension by diisocyanate condensation provides a versatile and convenient ...

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18.05.2013 | F. J. Jiménez‐Jiménez, H. Alonso‐Navarro, E. García‐Martín, O. Lorenzo‐Betancor, P. Pastor, J. A. G. Agúndez, Acta Neurologica Scandinavica, 2013

Despite the research, few advances in the etiopathogenesis on essential tremor (ET) have been made to date. The high frequency of positive family history of ET and the observed high concordance rates in monozygotic compared with dizygotic twins support a major role of genetic factors in the ...

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18.05.2013 | Mark Glover, Kevin M. O'Shaughnessy, Clinical and Experimental Pharmacology and Physiology, 2013

Abstract Human blood‐pressure is dependent on balancing dietary salt intake with its excretion by the kidney. Mendelian‐syndromes of altered blood pressure demonstrate the importance of the distal nephron in this process and of the thiazide‐sensitive pathway in ...

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