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16.063 Aktuelle Fachpublikationen zum Thema Addition

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Impact of sulfation pattern on the conformation and dynamics of sulfated fucan oligosaccharides as revealed by NMR and MD

01.05.2015 | Ismael NL Queiroz; Xiaocong Wang; John N Glushka; Gustavo RC Santos; Ana P Valente; James H Prestegard; Robert J Woo ..., Glycobiology , 2015

Sulfated fucans from sea urchin egg jelly express well-defined chemical structures that vary with species. This species specificity regulates the sperm acrosome reaction, a critical step to assure intra-specific fertilization. In addition, these polysaccharides are involved in other biological ...


SRD: a Staphylococcus regulatory RNA database [ARTICLES]

01.05.2015 | Mohamed Sassi; Yoann Augagneur; Tony Mauro; Lorraine Ivain; Svetlana Chabelskaya; Marc Hallier; Olivier Sallou; Bric ..., RNA, 2015

An overflow of regulatory RNAs (sRNAs) was identified in a wide range of bacteria. We designed and implemented a new resource for the hundreds of sRNAs identified in Staphylococci, with primary focus on the human pathogen Staphylococcus aureus. The "Staphylococcal Regulatory RNA Database" (SRD, ...


Intrahippocampal glutamine administration inhibits mTORC1 signaling and impairs long-term memory [RESEARCH]

01.05.2015 | Natalia S. Rozas; John B. Redell; Juan D. Pita-Almenar; James Mckenna III; Anthony N. Moore; Michael J. Gambello; Pr ..., Learning & Memory, 2015

The mechanistic Target of Rapamycin Complex 1 (mTORC1), a key regulator of protein synthesis and cellular growth, is also required for long-term memory formation. Stimulation of mTORC1 signaling is known to be dependent on the availability of energy and growth factors, as well as the presence of ...


Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease

01.05.2015 | Jing Jin; Qi Peng; Zhipeng Hou; Mali Jiang; Xin Wang; Abraham J. Langseth; Michael Tao; Peter B. Barker; Susumu Mori ..., Human Molecular Genetics, 2015

White matter abnormalities have been reported in premanifest Huntington's disease (HD) subjects before overt striatal neuronal loss, but whether the white matter changes represent a necessary step towards further pathology and the underlying mechanism of these changes remains unknown. Here, we ...


miRBoost: boosting support vector machines for microRNA precursor classification [BIOINFORMATICS]

01.05.2015 | Van Du T. Tran; Sebastien Tempel; Benjamin Zerath; Farida Zehraoui; Fariza Tahi, RNA, 2015

Identification of microRNAs (miRNAs) is an important step toward understanding post-transcriptional gene regulation and miRNA-related pathology. Difficulties in identifying miRNAs through experimental techniques combined with the huge amount of data from new sequencing technologies have made in ...


Using the Morris Water Maze to Assess Spatial Learning and Memory in Weanling Mice

17.04.2015 | Christopher D. Barnhart et al., PLoS ONE, 2015

by Christopher D. Barnhart, Dongren Yang, Pamela J. Lein Mouse models have been indispensable for elucidating normal and pathological processes that influence learning and memory. A widely used method for assessing these cognitive processes in mice is the Morris water maze, a classic test for ...


Transcript Dynamics at Early Stages of Molecular Interactions of MYMIV with Resistant and Susceptible Genotypes of the Leguminous Host, Vigna mungo

17.04.2015 | Anirban Kundu et al., PLoS ONE, 2015

by Anirban Kundu, Anju Patel, Sujay Paul, Amita Pal Initial phases of the MYMIV- Vigna mungo interaction is crucial in determining the infection phenotype upon challenging with the virus. During incompatible interaction, the plant deploys multiple stratagems that include extensive ...


Evaluation of the effect of Ultra Rice® EDTA supplementation on the soluble iron, visual acceptance and vitamin A stability of commercial milled rice blends

17.04.2015 | Paul W. Johns, Gaurav C. Patel, Megan E. Parker, John B. Lasekan, Peiman Milani, Melissa K. Nixon, Maryann Tigner, D ..., International Journal of Food Science & Technology, 2015

Summary The addition of NaFeEDTA at only 5% of total iron to ferric pyrophosphate‐fortified Ultra Rice® increased the in vitro soluble iron ten‐fold. Ultra Rice® formulated with NaFeEDTA at 2–7% of total iron, or with Na2EDTA·2H2O at 0.5× the total iron equivalents, increased the soluble iron ...


Effects of extrusion cooking on the dietary fibre content and Water Solubility Index of wheat bran extrudates

16.04.2015 | Summer Rashid, Allah Rakha, Faqir M. Anjum, Waqas Ahmed, Muhammad Sohail, International Journal of Food Science & Technology, 2015

Summary Instant study was an attempt to elucidate the suitability of wheat bran for extrusion cooking and to check the effect of different extrusion parameters on the dietary fibre profile as well as on water solubility index. Response surface methodology was used to optimise the extrusion ...


The lactate receptor, G‐protein‐coupled receptor 81/hydroxycarboxylic acid receptor 1: Expression and action in brain

16.04.2015 | Cecilie Morland, Knut Husø Lauritzen, Maja Puchades, Signe Holm‐Hansen, Krister Andersson, Albert Gjedde, Håvard Att ..., Journal of Neuroscience Research, 2015

We have proposed that lactate is a “volume transmitter” in the brain and underpinned this by showing that the lactate receptor, G‐protein‐coupled receptor 81 (GPR81, also known as HCA1 or HCAR1), which promotes lipid storage in adipocytes, is also active in the mammalian brain. This includes the ...


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