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18.076 Aktuelle Fachpublikationen zum Thema Addition

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Hyaluronan synthase assembles chitin oligomers with -GlcNAc({alpha}1->)UDP at the reducing end

01.06.2015 | Paul H Weigel; Christopher M West; Peng Zhao; Lance Wells; Bruce A Baggenstoss; Jennifer L Washburn, Glycobiology , 2015

Class I hyaluronan synthases (HASs) assemble a polysaccharide containing the repeating disaccharide [GlcNAc(β1,4)GlcUA(β1,3)]n-UDP and vertebrate HASs also assemble (GlcNAc-β1,4)n homo-oligomers (chitin) in the absence of GlcUA-UDP. This multi-membrane domain CAZy GT2 family glycosyltransferase, ...


Biallelic mutations in CAD, impair de novo pyrimidine biosynthesis and decrease glycosylation precursors

01.06.2015 | Bobby G. Ng; Lynne A. Wolfe; Mie Ichikawa; Thomas Markello; Miao He; Cynthia J. Tifft; William A. Gahl; Hudson H. Freeze, Human Molecular Genetics, 2015

In mitochondria, carbamoyl-phosphate synthetase 1 activity produces carbamoyl phosphate for urea synthesis, and deficiency results in hyperammonemia. Cytoplasmic carbamoyl-phosphate synthetase 2, however, is part of a tri-functional enzyme encoded by CAD; no human disease has been attributed to ...


The Synthesis and Photocatalytic Properties of TiO2 Nano‐Tube Array by Starch Modified Anodic Oxidation

23.05.2015 | Fengjun Zhang, Zijian Liu, Wei Lu, Cong Lyu, Chuan Lyu, Xiansheng Wang, Photochemistry and Photobiology, 2015

Abstract In this study, the characterization and photocatalytic activity of TiO2 nanotube arrays prepared by anodization process with starch addition were investigated in detail. The results suggested that the optimum mass fraction of starch added in anodization process was 0.1 %, with which ...


Impact of relationships between test and training animals and among training animals on reliability of genomic prediction

23.05.2015 | X. Wu, M.S. Lund, D. Sun, Q. Zhang, G. Su, Journal of Animal Breeding and Genetics, 2015

Summary One of the factors affecting the reliability of genomic prediction is the relationship among the animals of interest. This study investigated the reliability of genomic prediction in various scenarios with regard to the relationship between test and training animals, and among animals ...


East African pigs have a complex Indian, Far Eastern and Western ancestry

22.05.2015 | A. Noce, M. Amills, A. Manunza, V. Muwanika, D. Muhangi, T. Aliro, J. Mayega, R. Ademun, A. Sànchez, S. Egbhalsaied, ..., Animal Genetics, 2015

Summary In this study, we have characterized the mitochondrial diversity of 81 swine from Uganda. Median‐joining network analysis of D‐loop sequences from these individuals and others characterized in previous studies allowed us to determine that Ugandan pigs cluster with populations from the ...


Birth prevalence of Robin sequence in the Netherlands from 2000‐2010: A retrospective population‐based study in a large Dutch cohort and review of the literature

21.05.2015 | Emma C. Paes, Daan P. F. van Nunen, Hanneke Basart, J. Peter W. Don Griot, Johanna M. van Hagen, Chantal M. A. M. va ..., American Journal of Medical Genetics Part A, 2015

The birth prevalence of Robin sequence (RS) is frequently cited to be 1 in 8,500 to 14,000 live births (range: 7,1–11,8 per 100.000), which is based on just a few epidemiological studies. The objective of this study is to contribute to the limited knowledge of the epidemiology of RS by ...


Impact of a Multifaceted Intervention on Promoting Adherence to Screening Colonoscopy Among Persons in HIV Primary Care: A Pilot Study

21.05.2015 | Pansy Ferron, Shihab S. Asfour, Lisa R. Metsch, Michael H. Antoni, Allan E. Rodriguez, Robert Duncan, Sheila M. Findlay, Clinical and Translational Science, 2015

Abstract HIV‐positive patients have lower colon cancer screening rates and are at increased risk for colon adenocarcinoma. We tested a transdisciplinary prevention model to increase provider and patient adherence to screening colonoscopy. Of 1,339 HIV‐positive patients with scheduled clinic ...


Bioactive Self‐Assembling Lipid‐Like Peptides as Permeation Enhancers for Oral Drug Delivery

21.05.2015 | Christina Karavasili, Marios Spanakis, Dionysia Papagiannopoulou, Ioannis S. Vizirianakis, Dimitrios G. Fatouros, So ..., Journal of Pharmaceutical Sciences, 2015

Amphiphilic, lipid‐like, self‐assembling peptides are functional biomaterials with surfactant properties. In this work, lipid‐like peptides were designed to have a hydrophilic head composed of aspartic acid or lysine and a six alanine residue hydrophobic domain and have a length similar to that ...


Inhibitory effect of super‐hydrophobicity on silver release and antibacterial properties of super‐hydrophobic Ag/TiO2 nanotubes

20.05.2015 | Licheng Zhang, Lihai Zhang, Yun Yang, Wei Zhang, Houchen Lv, Fei Yang, Changjian Lin, Peifu Tang, Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2015

Abstract The antibacterial properties of super‐hydrophobic silver (Ag) on implant surface have not yet to be fully illuminated. In our study, we investigate the protective effects of super‐hydrophobic coating of silver/titanium dioxide (Ag/TiO2) nanotubes against bacterial pathogens, as well ...


Optimization of isolation and cultivation of bacterial endophytes through addition of plant extract to nutrient media

20.05.2015 | N. Eevers, M. Gielen, A. Sánchez‐López, S. Jaspers, J. C. White, J. Vangronsveld, N. Weyens, Microbial Biotechnology, 2015

Summary Many endophytes have beneficial effects on plants and can be exploited in biotechnological applications. Studies hypothesize that only 0.001–1% of all plant‐associated bacteria are cultivable. Moreover, even after successful isolations, many endophytic bacteria often show reduced ...


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