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Atherogenesis: hyperhomocysteinemia interactions with LDL, macrophage function, paraoxonase 1, and exercise

05.02.2016 | Ilya Chernyavskiy, Sudhakar Veeranki, Utpal Sen, Suresh C. Tyagi, Annals of the New York Academy of Sciences, 2016

Despite great strides in understanding the atherogenesis process, the mechanisms are not entirely known. In addition to diet, cigarette smoking, genetic predisposition, and hypertension, hyperhomocysteinemia (HHcy), an accumulation of the noncoding sulfur‐containing amino acid homocysteine ...


GAD2 Alternative Transcripts in the Human Prefrontal Cortex, and in Schizophrenia and Affective Disorders

05.02.2016 | Kasey N. Davis et al., PLoS ONE, 2016

by Kasey N. Davis, Ran Tao, Chao Li, Yuan Gao, Marjorie C. Gondré-Lewis, Barbara K. Lipska, Joo Heon Shin, Bin Xie, Tianzhang Ye, Daniel R. Weinberger, Joel E. Kleinman, Thomas M. Hyde Genetic variation and early adverse environmental events work together to increase risk for schizophrenia. ...


Xenobiotic Compounds Degradation by Heterologous Expression of a Trametes sanguineus Laccase in Trichoderma atroviride

05.02.2016 | Edgar Balcázar-López et al., PLoS ONE, 2016

by Edgar Balcázar-López, Luz Helena Méndez-Lorenzo, Ramón Alberto Batista-García, Ulises Esquivel-Naranjo, Marcela Ayala, Vaidyanathan Vinoth Kumar, Olivier Savary, Hubert Cabana, Alfredo Herrera-Estrella, Jorge Luis Folch-Mallol Fungal laccases are enzymes that have been studied because of ...


[Neurobiology] Synaptic Signaling in Learning and Memory

01.02.2016 | Mary B. Kennedy, CSH Perspectives, 2016

Learning and memory require the formation of new neural networks in the brain. A key mechanism underlying this process is synaptic plasticity at excitatory synapses, which connect neurons into networks. Excitatory synaptic transmission happens when glutamate, the excitatory neurotransmitter, ...


Energies, Vol. 9, Pages 89: Field Study on Humidification Performance of a Desiccant Air-Conditioning System Combined with a Heat Pump

30.01.2016 | Kawamoto, Koichi ; Cho, Wanghee ; Kohno, Hitoshi ; Koganei, Makoto ; Ooka, Ryozo ; Kato, Shinsuke, Energies, 2016

A desiccant air-conditioning system was developed as a latent-load-processing air conditioner in a dedicated outdoor air system during the summer. This study investigated the application of this air-conditioning system to humidification during the winter without using make-up water, thereby ...


[Report] Oxygen isotopic evidence for vigorous mixing during the Moon-forming giant impact

29.01.2016 | Edward D. Young; Issaku E. Kohl; Paul H. Warren; David C. Rubie; Seth A. Jacobson; Alessandro Morbidelli, Science , 2016

Earth and the Moon are shown here to have indistinguishable oxygen isotope ratios, with a difference in Δ′17O of −1 ± 5 parts per million (2 standard error). On the basis of these data and our new planet formation simulations that include a realistic model for primordial oxygen isotopic ...


Cth2 Protein Mediates Early Adaptation of Yeast Cells to Oxidative Stress Conditions

29.01.2016 | Laia Castells-Roca et al., PLoS ONE, 2016

by Laia Castells-Roca, Jordi Pijuan, Francisco Ferrezuelo, Gemma Bellí, Enrique Herrero Cth2 is an mRNA-binding protein that participates in remodeling yeast cell metabolism in iron starvation conditions by promoting decay of the targeted molecules, in order to avoid excess iron consumption. ...


BJ-1108, a 6-Amino-2,4,5-Trimethylpyridin-3-ol Analog, Inhibits Serotonin-Induced Angiogenesis and Tumor Growth through PI3K/NOX Pathway

29.01.2016 | Suhrid Banskota et al., PLoS ONE, 2016

by Suhrid Banskota, Jaya Gautam, Sushil C. Regmi, Pallavi Gurung, Myo-Hyeon Park, Seung Joo Kim, Tae-gyu Nam, Byeong-Seon Jeong, Jung-Ae Kim 5-Hydroxytryptamine (5-HT) induces proliferation of cancer cells and vascular cells. In addition to 5-HT production by several cancer cells including ...


The Species and Origin of Shark Fins in Taiwan’s Fishing Ports, Markets, and Customs Detention: A DNA Barcoding Analysis

22.01.2016 | Po-Shun Chuang et al., PLoS ONE, 2016

by Po-Shun Chuang, Tzu-Chiao Hung, Hung-An Chang, Chien-Kang Huang, Jen-Chieh Shiao The increasing consumption of shark products, along with the shark’s fishing vulnerabilities, has led to the decrease in certain shark populations. In this study we used a DNA barcoding method to identify the ...


Development of a RAD-Seq Based DNA Polymorphism Identification Software, AgroMarker Finder, and Its Application in Rice Marker-Assisted Breeding

22.01.2016 | Wei Fan et al., PLoS ONE, 2016

by Wei Fan, Jie Zong, Zhijing Luo, Mingjiao Chen, Xiangxiang Zhao, Dabing Zhang, Yiping Qi, Zheng Yuan Rapid and accurate genome-wide marker detection is essential to the marker-assisted breeding and functional genomics studies. In this work, we developed an integrated software, AgroMarker ...


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