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2.030 Aktuelle Fachpublikationen zum Thema Addition

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Outflow Boundary Conditions for Blood Flow in Arterial Trees

22.05.2015 | Tao Du et al., PLoS ONE, 2015

by Tao Du, Dan Hu, David Cai In the modeling of the pulse wave in the systemic arterial tree, it is necessary to truncate small arterial crowns representing the networks of small arteries and arterioles. Appropriate boundary conditions at the truncation points are required to represent wave ...

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Tumor Necrosis Factor-α-Induced Ototoxicity in Mouse Cochlear Organotypic Culture

22.05.2015 | Qian Wu et al., PLoS ONE, 2015

by Qian Wu, Guo-Peng Wang, Jing Xie, Jing-Ying Guo, Shu-Sheng Gong Tumor necrosis factor (TNF)-α is a cytokine involved in acute inflammatory phase reactions, and is the primary upstream mediator in the cochlear inflammatory response. Treatment of the organ of Corti with TNF-α can induce hair ...

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ProteINSIDE to Easily Investigate Proteomics Data from Ruminants: Application to Mine Proteome of Adipose and Muscle Tissues in Bovine Foetuses

22.05.2015 | Nicolas Kaspric et al., PLoS ONE, 2015

by Nicolas Kaspric, Brigitte Picard, Matthieu Reichstadt, Jérémy Tournayre, Muriel Bonnet Genomics experiments are widely acknowledged to produce a huge amount of data to be analysed. The challenge is to extract meaningful biological context for proteins or genes which is currently difficult ...

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The EGFR/ErbB3 Pathway Acts as a Compensatory Survival Mechanism upon c-Met Inhibition in Human c-Met + Hepatocellular Carcinoma

22.05.2015 | Steven N. Steinway et al., PLoS ONE, 2015

by Steven N. Steinway, Hien Dang, Hanning You, C. Bart Rountree, Wei Ding Background c-Met, a high-affinity receptor for Hepatocyte Growth Factor (HGF), plays a critical role in tumor growth, invasion, and metastasis. Hepatocellular carcinoma (HCC) patients with activated HGF/c-Met signaling ...

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[In Depth] Leaf bacteria fertilize trees, researchers claim

22.05.2015 | Elizabeth Pennisi, Science , 2015

One of the fastest growing trees, poplars, may rely on tiny microbes in their leaves to fuel their growth. For more than a decade, a lone researcher has been building a case for nitrogen fixation by bacteria living in poplar leaves. There have been many claims of nitrogen fixation in plants ...

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Corrigendum: Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

21.05.2015 | Jaime N. Guzman; Javier Sanchez-Padilla; David Wokosin; Jyothisri Kondapalli; Ema Ilijic; Paul T. Schumacker; D. Jam ..., Nature, 2015

Corrigendum: Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1 Nature 521, 7552 (2015). doi:10.1038/nature14487 Authors: Jaime N. Guzman, Javier Sanchez-Padilla, David Wokosin, Jyothisri Kondapalli, Ema Ilijic, ...

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Potential Transmission Pathways of Streptococcus gallolyticus subsp. gallolyticus

15.05.2015 | Jessika Dumke et al., PLoS ONE, 2015

by Jessika Dumke, Dennis Hinse, Tanja Vollmer, Jochen Schulz, Cornelius Knabbe, Jens Dreier Streptococcus gallolyticus subsp. gallolyticus (S. gallolyticus subsp. gallolyticus), a member of group D streptococci, is an inhabitant of the animal and human gastrointestinal tract. Furthermore, it is ...

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Subunits of the Pyruvate Dehydrogenase Cluster of Mycoplasma pneumoniae Are Surface-Displayed Proteins that Bind and Activate Human Plasminogen

15.05.2015 | Anne Gründel et al., PLoS ONE, 2015

by Anne Gründel, Kathleen Friedrich, Melanie Pfeiffer, Enno Jacobs, Roger Dumke The dual role of glycolytic enzymes in cytosol-located metabolic processes and in cell surface-mediated functions with an influence on virulence is described for various micro-organisms. Cell wall-less bacteria of ...

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Contributions of T Lymphocyte Abnormalities to Therapeutic Outcomes in Newly Diagnosed Patients with Immune Thrombocytopenia

15.05.2015 | Zhenhua Zhao et al., PLoS ONE, 2015

by Zhenhua Zhao, Lei Yang, Guohua Yang, Yun Zhuang, Xifeng Qian, Xin Zhou, Dajiang Xiao, Yunfeng Shen T cell abnormalities have been reported to play an important role in pathogenesis of immune thrombocytopenia (ITP) besides specific autoantibodies towards platelet. The aim of this study was to ...

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Silica Triggers Inflammation and Ectopic Lymphoid Neogenesis in the Lungs in Parallel with Accelerated Onset of Systemic Autoimmunity and Glomerulonephritis in the Lupus-Prone NZBWF1 Mouse

15.05.2015 | Melissa A. Bates et al., PLoS ONE, 2015

by Melissa A. Bates, Christina Brandenberger, Ingeborg Langohr, Kazuyoshi Kumagai, Jack R. Harkema, Andrij Holian, James J. Pestka Genetic predisposition and environmental factors influence the development of human autoimmune disease. Occupational exposure to crystalline silica (cSiO2) has been ...

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