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1.994 Aktuelle Fachpublikationen zum Thema Addition

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Using the Morris Water Maze to Assess Spatial Learning and Memory in Weanling Mice

17.04.2015 | Christopher D. Barnhart et al., PLoS ONE, 2015

by Christopher D. Barnhart, Dongren Yang, Pamela J. Lein Mouse models have been indispensable for elucidating normal and pathological processes that influence learning and memory. A widely used method for assessing these cognitive processes in mice is the Morris water maze, a classic test for ...


Transcript Dynamics at Early Stages of Molecular Interactions of MYMIV with Resistant and Susceptible Genotypes of the Leguminous Host, Vigna mungo

17.04.2015 | Anirban Kundu et al., PLoS ONE, 2015

by Anirban Kundu, Anju Patel, Sujay Paul, Amita Pal Initial phases of the MYMIV- Vigna mungo interaction is crucial in determining the infection phenotype upon challenging with the virus. During incompatible interaction, the plant deploys multiple stratagems that include extensive ...


Long Term Effect of Curcumin in Restoration of Tumour Suppressor p53 and Phase-II Antioxidant Enzymes via Activation of Nrf2 Signalling and Modulation of Inflammation in Prevention of Cancer

10.04.2015 | Laxmidhar Das et al., PLoS ONE, 2015

by Laxmidhar Das, Manjula Vinayak Inhibition of carcinogenesis may be a consequence of attenuation of oxidative stress via activation of antioxidant defence system, restoration and stabilization of tumour suppressor proteins along with modulation of inflammatory mediators. Previously we have ...


Acceleration of Vascular Sprouting from Fabricated Perfusable Vascular-Like Structures

10.04.2015 | Tatsuya Osaki et al., PLoS ONE, 2015

by Tatsuya Osaki, Takahiro Kakegawa, Tatsuto Kageyama, Junko Enomoto, Tadashi Nittami, Junji Fukuda Fabrication of vascular networks is essential for engineering three-dimensional thick tissues and organs in the emerging fields of tissue engineering and regenerative medicine. In this study, we ...


Personalized health care beyond oncology: new indications for immunoassay‐based companion diagnostics

09.04.2015 | Richard Batrla, Bruce W.M. Jordan, Annals of the New York Academy of Sciences, 2015

Personalized health care (PHC) is an evolving field of medicine aimed at providing the right therapy to the right patient at the right time. This approach often incorporates the use of companion diagnostics (CDx) assays that provide information essential for the safe and effective use of the ...


[Report] Mutation rate and genotype variation of Ebola virus from Mali case sequences

03.04.2015 | T. Hoenen; D. Safronetz; A. Groseth; K. R. Wollenberg; O. A. Koita; B. Diarra; I. S. Fall; F. C. Haidara; F. Diallo; ..., Science , 2015

The occurrence of Ebola virus (EBOV) in West Africa during 2013–2015 is unprecedented. Early reports suggested that in this outbreak EBOV is mutating twice as fast as previously observed, which indicates the potential for changes in transmissibility and virulence and could render current ...


[Special Issue Review] Adoptive cell transfer as personalized immunotherapy for human cancer

03.04.2015 | Steven A. Rosenberg; Nicholas P. Restifo, Science , 2015

Adoptive cell therapy (ACT) is a highly personalized cancer therapy that involves administration to the cancer-bearing host of immune cells with direct anticancer activity. ACT using naturally occurring tumor-reactive lymphocytes has mediated durable, complete regressions in patients with ...


Associations of Sedentary Behaviour, Physical Activity, Blood Pressure and Anthropometric Measures with Cardiorespiratory Fitness in Children with Cerebral Palsy

02.04.2015 | Jennifer M. Ryan et al., PLoS ONE, 2015

by Jennifer M. Ryan, Owen Hensey, Brenda McLoughlin, Alan Lyons, John Gormley Background Children with cerebral palsy (CP) have poor cardiorespiratory fitness in comparison to their peers with typical development, which may be due to low levels of physical activity. Poor cardiorespiratory ...


Small Molecule Inhibitor of Formin Homology 2 Domains (SMIFH2) Reveals the Roles of the Formin Family of Proteins in Spindle Assembly and Asymmetric Division in Mouse Oocytes

02.04.2015 | Hak-Cheol Kim et al., PLoS ONE, 2015

by Hak-Cheol Kim, Yu-Jin Jo, Nam-Hyung Kim, Suk Namgoong Dynamic actin reorganization is the main driving force for spindle migration and asymmetric cell division in mammalian oocytes. It has been reported that various actin nucleators including Formin-2 are involved in the polarization of the ...


A TatABC-Type Tat Translocase Is Required for Unimpaired Aerobic Growth of Corynebacterium glutamicum ATCC13032

02.04.2015 | Dan Oertel et al., PLoS ONE, 2015

by Dan Oertel, Sabrina Schmitz, Roland Freudl The twin-arginine translocation (Tat) system transports folded proteins across the cytoplasmic membrane of bacteria and the thylakoid membrane of plant chloroplasts. Escherichia coli and other Gram-negative bacteria possess a TatABC-type Tat ...


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