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1.923 Aktuelle Fachpublikationen zum Thema Addition

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Seasonal Photochemical Transformations of Nitrogen Species in a Forest Stream and Lake

31.12.2014 | Petr Porcal et al., PLoS ONE, 2014

by Petr Porcal, Jiří Kopáček, Iva Tomková The photochemical release of inorganic nitrogen from dissolved organic matter is an important source of bio-available nitrogen (N) in N-limited aquatic ecosystems. We conducted photochemical experiments and used mathematical models based on ...

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Hot Fusion: An Efficient Method to Clone Multiple DNA Fragments as Well as Inverted Repeats without Ligase

31.12.2014 | Changlin Fu et al., PLoS ONE, 2014

by Changlin Fu, William P. Donovan, Olga Shikapwashya-Hasser, Xudong Ye, Robert H. Cole Molecular cloning is utilized in nearly every facet of biological and medical research. We have developed a method, termed Hot Fusion, to efficiently clone one or multiple DNA fragments into plasmid vectors ...

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Frontotemporal dementia: a bridge between dementia and neuromuscular disease

30.12.2014 | Adeline S.L. Ng, Rosa Rademakers, Bruce L. Miller, Annals of the New York Academy of Sciences, 2014

The concept that frontotemporal dementia (FTD) is a purely cortical dementia has largely been refuted by the recognition of its close association with motor neuron disease, and the identification of transactive response DNA‐binding protein 43 (TDP‐43) as a major pathological substrate underlying ...

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PTEN signaling through RAF1 proto-oncogene serine/threonine kinase (RAF1)/ERK in the epididymis is essential for male fertility [Developmental Biology]

30.12.2014 | Bingfang Xu; Angela M. Washington; Barry T. Hinton, Proceedings of the National Academy of Sciences current issue, 2014

Without a fully developed initial segment, the most proximal region of the epididymis, male infertility results. Therefore, it is important to understand the development and regulation of this crucial region. In addition to distinctively high activity levels of the components of the ERK pathway, ...

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Structural basis of HIV-1 capsid recognition by PF74 and CPSF6 [Biophysics and Computational Biology]

30.12.2014 | Akash Bhattacharya; Steven L. Alam; Thomas Fricke; Kaneil Zadrozny; Jaroslaw Sedzicki; Alexander B. Taylor; Borries ..., Proceedings of the National Academy of Sciences current issue, 2014

Upon infection of susceptible cells by HIV-1, the conical capsid formed by ∼250 hexamers and 12 pentamers of the CA protein is delivered to the cytoplasm. The capsid shields the RNA genome and proteins required for reverse transcription. In addition, the surface of the capsid mediates numerous ...

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Identification of Genes Associated with Reproduction in the Mud Crab (Scylla olivacea) and Their Differential Expression following Serotonin Stimulation

26.12.2014 | Napamanee Kornthong et al., PLoS ONE, 2014

by Napamanee Kornthong, Scott F. Cummins, Charoonroj Chotwiwatthanakun, Kanjana Khornchatri, Attakorn Engsusophon, Peter J. Hanna, Prasert Sobhon The central nervous system (CNS) is often intimately involved in reproduction control and is therefore a target organ for transcriptomic ...

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Four Dimensional Digital Tomosynthesis Using on-Board Imager for the Verification of Respiratory Motion

26.12.2014 | Justin C. Park et al., PLoS ONE, 2014

by Justin C. Park, Jin Sung Kim, Sung Ho Park, Matthew J. Webster, Soyoung Lee, William Y. Song, Youngyih Han Purpose To evaluate respiratory motion of a patient by generating four-dimensional digital tomosynthesis (4D DTS), extracting respiratory signal from patients' on-board projection data, ...

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The Roles of Co-Chaperone CCRP/DNAJC7 in Cyp2b10 Gene Activation and Steatosis Development in Mouse Livers

26.12.2014 | Marumi Ohno et al., PLoS ONE, 2014

by Marumi Ohno, Tomohiko Kanayama, Rick Moore, Manas Ray, Masahiko Negishi Cytoplasmic constitutive active/androstane receptor (CAR) retention protein (CCRP and also known as DNAJC7) is a co-chaperone previously characterized to retain nuclear receptor CAR in the cytoplasm of HepG2 cells. Here ...

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Evidence for the Involvement of Loosely Bound Plastosemiquinones in Superoxide Anion Radical Production in Photosystem II

26.12.2014 | Deepak Kumar Yadav et al., PLoS ONE, 2014

by Deepak Kumar Yadav, Ankush Prasad, Jerzy Kruk, Pavel Pospíšil Recent evidence has indicated the presence of novel plastoquinone-binding sites, QC and QD, in photosystem II (PSII). Here, we investigated the potential involvement of loosely bound plastosemiquinones in superoxide anion radical ...

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Production of Novel Antibiotics Zeamines through Optimizing Dickeya zeae Fermentation Conditions

26.12.2014 | Lisheng Liao et al., PLoS ONE, 2014

by Lisheng Liao, Yingying Cheng, Shiyin Liu, Jianuan Zhou, Shuwen An, Mingfa Lv, Yufan Chen, Yanfang Gu, Shaohua Chen, Lian-Hui Zhang Dickeya zeae strain EC1 was recently shown to produce a new type of phytotoxins designated as zeamine and zeamine II, which are potent wide-spectrum antibiotics ...

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