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6.872 Aktuelle Fachpublikationen zum Thema Addition

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Surface expression patterns of defined glycan antigens change during Schistosoma mansoni cercarial transformation and development of schistosomula

01.12.2015 | Cornelis H Smit; Arne Homann; Vincent P van Hensbergen; Gabriele Schramm; Helmut Haas; Angela van Diepen; Cornelis H ..., Glycobiology , 2015

During the complex lifecycle of Schistosoma mansoni, a large variety of glycans is expressed. To many of these glycans, antibodies are induced by the infected host and some might be targets for vaccines or diagnostic tests. Spatial changes in glycan expression during schistosome development are ...


The regulation of ER export and Golgi retention of ST3Gal5 (GM3/GM4 synthase) and B4GalNAcT1 (GM2/GD2/GA2 synthase) by arginine/lysine-based motif adjacent to the transmembrane domain

01.12.2015 | Satoshi Uemura; Fumi Shishido; Madoka Kashimura; Jin-ichi Inokuchi, Glycobiology , 2015

In the Golgi maturation model, the Golgi cisternae dynamically mature along a secretory pathway. In this dynamic process, glycosyltransferases are transported from the endoplasmic reticulum (ER) to the Golgi apparatus where they remain and function. The precise mechanism behind this maturation ...


Similarity of Crocodilian and Avian Lungs Indicates Unidirectional Flow Is Ancestral for Archosaurs

01.12.2015 | C. G. Farmer, Integrative and Comparative Biology, 2015

Patterns of airflow and pulmonary anatomy were studied in the American alligator (Alligator mississippiensis), the black caiman (Melanosuchus niger), the spectacled caiman (Caiman crocodilus), the dwarf crocodile (Osteolaemus tetraspis), the saltwater crocodile (Crocodylus porosus), the Nile ...


Molecular Evidence for Convergence and Parallelism in Evolution of Complex Brains of Cephalopod Molluscs: Insights from Visual Systems

01.12.2015 | M. A. Yoshida; A. Ogura; K. Ikeo; S. Shigeno; T. Moritaki; G. C. Winters; A. B. Kohn; L. L. Moroz, Integrative and Comparative Biology, 2015

Coleoid cephalopods show remarkable evolutionary convergence with vertebrates in their neural organization, including (1) eyes and visual system with optic lobes, (2) specialized parts of the brain controlling learning and memory, such as vertical lobes, and (3) unique vasculature supporting such ...


MEPSA: minimum energy pathway analysis for energy landscapes

01.12.2015 | Iñigo Marcos-Alcalde; Javier Setoain; Jesús I. Mendieta-Moreno; Jesús Mendieta; Paulino Gómez-Puertas, Bioinformatics, 2015

Summary: From conformational studies to atomistic descriptions of enzymatic reactions, potential and free energy landscapes can be used to describe biomolecular systems in detail. However, extracting the relevant data of complex 3D energy surfaces can sometimes be laborious. In this article, we ...


Cholesterol loading in vivo and in vitro alters extracellular matrix proteins production in smooth muscle cells

21.11.2015 | Rogelio Palomino‐Morales, Sonia Perales, Carolina Torres, Ana Linares, Maria Jose Alejandre, European Journal of Lipid Science and Technology, 2015

Abstract This study supports the SMC dedifferentiation in vitro model and increases our fundamental knowledge of plaque formation and remodeling. With this purpose, we isolated smooth muscle cells form aortic arch of chicks either fed under control or high cholesterol diets. From the former ...


Saturated branched fatty compounds: Proven industrial processes and new alternatives

20.11.2015 | Jennifer Haßelberg, Arno Behr, European Journal of Lipid Science and Technology, 2015

Abstract This paper reviews properties and synthesis of saturated branched fatty compounds and their application. Especially industrially established processes based on the Guerbet reaction, Fatty acid isomerization, Oxo‐ and Koch synthesis will be presented. Also new laboratory methods will ...


The patulin is a cultivar dependent aggressiveness factor favoring the colonization of apples by Penicillium expansum

19.11.2015 | Selma P. Snini, Joanna Tannous, Pauline Heuillard, Sylviane Bailly, Yannick Lippi, Enric Zehraoui, Christian Barreau ..., Molecular Plant Pathology, 2015

Abstract The blue mold decay of apples is caused by Penicillium expansum and associated with the contamination of patulin, a worldwide regulated mycotoxin. Recently, a cluster of the 15 genes (patA‐patO) involved in patulin biosynthesis was identified in P. expansum. BLAST analysis revealed ...


A Bio-inspired Collision Avoidance Model Based on Spatial Information Derived from Motion Detectors Leads to Common Routes

19.11.2015 | Olivier J. N. Bertrand et al., PLoS Computational Biology, 2015

by Olivier J. N. Bertrand, Jens P. Lindemann, Martin Egelhaaf Avoiding collisions is one of the most basic needs of any mobile agent, both biological and technical, when searching around or aiming toward a goal. We propose a model of collision avoidance inspired by behavioral experiments on ...


C5a inhibitor protects ischemia/reperfusion injury in rat small intestine

18.11.2015 | Eszter Tuboly, Mitsuru Futakuchi, Gabriella Varga, Dániel Érces, Tünde Tőkés, András Mészáros, József Kaszaki, Masum ..., Microbiology and Immunology, 2015

Abstract Acute mesenteric ischemia (AMI) is caused by considerable injury in the intestine, which is associated with intestinal ischemia followed by reperfusion (Treat‐I/R). To elucidate the mechanisms of I/R injury, we examined role of C5a anaphylatoxin using a C5a inhibitory peptide termed ...


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