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6.163 Aktuelle Fachpublikationen zum Thema Addition

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Antitumor properties of a new non-anticoagulant heparin analog from the mollusk Nodipecten nodosus: Effect on P-selectin, heparanase, metastasis and cellular recruitment

01.04.2015 | Angélica Maciel Gomes; Eliene Oliveira Kozlowski; Lubor Borsig; Felipe C O B Teixeira; Israel Vlodavsky; Mauro S G Pavão, Glycobiology , 2015

Inflammation and cancer are related pathologies acting synergistically to promote tumor progression. In both, hematogenous metastasis and inflammation, P-selectin participates in interactions involving tumor cells, platelets, leukocytes and endothelium. Heparin has been shown to inhibit ...


Conserved ion and amino acid transporters identified as phosphorylcholine-modified N-glycoproteins by metabolic labeling with propargylcholine in Caenorhabditis elegans cells

01.04.2015 | Casey J Snodgrass; Amanda R Burnham-Marusich; John C Meteer; Patricia M Berninsone, Glycobiology , 2015

Phosphorylcholine (PC) modification of proteins by pathogens has been implicated in mediating host–pathogen interactions. Parasitic nematodes synthesize PC-modified biomolecules that can modulate the host's antibody and cytokine production to favor nematode survival, contributing to long-term ...


Enzymatic properties and subtle differences in the substrate specificity of phylogenetically distinct invertebrate N-glycan processing hexosaminidases

01.04.2015 | Martin Dragosits; Shi Yan; Ebrahim Razzazi-Fazeli; Iain B H Wilson; Dubravko Rendic, Glycobiology , 2015

Fused lobes (FDL) hexosaminidases are the most recently genetically defined glycosidases involved in the biosynthesis of N-glycans in invertebrates, and their narrow specificity is essential for the generation of paucimannosidic N-glycans in insects. In this study, we explored the potential of ...


Development of genome‐wide insertion/deletion markers in rice based on graphic pipeline platform

21.03.2015 | Yang Lü, Xiao Cui, Rui Li, Piaopiao Huang, Jie Zong, Danqing Yao, Gang Li, Dabing Zhang, Zheng Yuan, Journal of Integrative Plant Biology, 2015

Abstract DNA markers play important roles in plant breeding and genetics. Insertion/Deletion (InDel) marker is one kind of co‐dominant DNA markers widely used since low cost and high precision. However, canonical way of searching for InDel markers is time‐consuming and labor‐intensive. We ...


Chitosan Grafted with Phosphorylcholine and Macrocyclic Polyamine as an Effective Gene Delivery Vector: Preparation, Characterization and In Vitro Transfection

20.03.2015 | Ling Li, Fangfang Zhao, Baojing Zhao, Jin Zhang, Chao Li, Renzhong Qiao, Macromolecular Bioscience, 2015

Herein, an effective gene delivery vector phosphorylcholine and macrocyclic polyamine grafted chitosan (PC‐g(6)‐Cs‐g(2)‐Cyclen) was developed. Chemical characterization of product PC‐g(6)‐Cs‐g(2)‐Cyclen was performed by NMR, FT‐IR, gel permeation chromatography (GPC), and X‐ray photoelectron ...


Viruses, Vol. 7, Pages 1332-1343: Human Papillomavirus and Tonsillar and Base of Tongue Cancer

20.03.2015 | Ramqvist, Torbjörn ; Grün, Nathalie ; Dalianis, Tina, Viruses, 2015

In 2007, human papillomavirus (HPV) type 16 was recognized as a risk factor by the International Agency for Research on Cancer, for oropharyngeal squamous cell carcinoma (OSCC), where tonsillar and base of tongue cancer (TSCC and BOTSCC) dominate. Furthermore, patients with HPV-positive TSCC and ...


Simultaneous Extraction of Phosphatidylcholine and Phosphatidylethanolamine from Soybean Lecithin

19.03.2015 | Johnson V. John, Huiju Park, Hye Ri Lee, Hongsuk Suh, Il Kim, European Journal of Lipid Science and Technology, 2015

A high composition of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) was simultaneously extracted from soybean lecithin by using a mixed solvent consisting of ethanol and chloroform. The addition of chloroform in ethanol improved the total extraction yield to give high composition ...


Viruses, Vol. 7, Pages 1284-1312: The Cryptophlebia Leucotreta Granulovirus—10 Years of Commercial Field Use

19.03.2015 | Moore, Sean D.; Kirkman, Wayne ; Richards, Garth I.; Stephen, Peter R., Viruses, 2015

In the last 15 years, extensive work on the Cryptophlebia leucotreta granulovirus (CrleGV) has been conducted in South Africa, initially in the laboratory, but subsequently also in the field. This culminated in the registration of the first CrleGV-based biopesticide in 2004 (hence, the 10 years ...


The incorporation of plant materials in “Serra da Estrela” cheese improves antioxidant activity without changing the fatty acid profile and visual appearance

16.03.2015 | Márcio Carocho, João C.M. Barreira, Amilcar L. Antonio, Albino Bento, Patricia Morales, Isabel C.F.R. Ferreira, European Journal of Lipid Science and Technology, 2015

“Serra da Estrela” cheese is a Portuguese delicacy, which has been produced for centuries from the milk of cattle pasturing in the protected Serra da Estrela natural park. Transforming this cheese into a functional food would be a huge benefit for the market and the consumer. Decocted extracts ...


The role of iron in peroxidation of PUFA: effect of pH and chelators

16.03.2015 | Revilija Mozuraityte, Vera Kristinova, Turid Rustad, Ivar Storrø, European Journal of Lipid Science and Technology, 2015

The aim of this work was to understand the effect of pH and chelators on free iron (Fe2+/Fe3+)‐mediated oxidation in liposome dispersions made of marine phospholipids. Consumption of dissolved oxygen was used to follow lipid oxidation. The highest oxygen uptake rates were found at pH 4 ‐ 5. ...


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