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7.605 Aktuelle Fachpublikationen in PLoS ONE

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Dysregulated Autophagy Contributes to Podocyte Damage in Fabry’s Disease

17.05.2013 | Max C. Liebau et al., PLoS ONE, 2013

by Max C. Liebau, Fabian Braun, Katja Höpker, Claudia Weitbrecht, Valerie Bartels, Roman-Ulrich Müller, Susanne Brodesser, Moin A. Saleem, Thomas Benzing, Bernhard Schermer, Markus Cybulla, Christine E. Kurschat Fabry’s disease results from an inborn error of glycosphingolipid metabolism ...

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Mitochondrial Respiratory Pathways Inhibition in Rhizopus oryzae Potentiates Activity of Posaconazole and Itraconazole via Apoptosis

17.05.2013 | Fazal Shirazi et al., PLoS ONE, 2013

by Fazal Shirazi, Dimitrios P. Kontoyiannis The incidence of mucormycosis has increased drastically in immunocompromised patients. Also the array of targets whose inhibition results in Mucorales death is limited. Recently, researchers identified mitochondria as important regulators of ...

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Effects of Pharmacists' Interventions on Appropriateness of Prescribing and Evaluation of the Instruments' (MAI, STOPP and STARTs') Ability to Predict Hospitalization–Analyses from a Randomized Controlled Trial

17.05.2013 | Ulrika Gillespie et al., PLoS ONE, 2013

by Ulrika Gillespie, Anna Alassaad, Margareta Hammarlund-Udenaes, Claes Mörlin, Dan Henrohn, Maria Bertilsson, Håkan Melhus Background Appropriateness of prescribing can be assessed by various measures and screening instruments. The aims of this study were to investigate the effects of ...

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Zinc Transporter 8 and MAP3865c Homologous Epitopes are Recognized at T1D Onset in Sardinian Children

17.05.2013 | Speranza Masala et al., PLoS ONE, 2013

by Speranza Masala, Maria Antonietta Zedda, Davide Cossu, Carlo Ripoli, Mario Palermo, Leonardo A. Sechi Our group has recently demonstrated that Mycobacterium avium subspecies paratuberculosis (MAP) infection significantly associates with T1D in Sardinian adult patients. Due to the ...

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Use of Fat Mass and Fat Free Mass Standard Deviation Scores Obtained Using Simple Measurement Methods in Healthy Children and Patients: Comparison with the Reference 4-Component Model

17.05.2013 | Rachel R. Atherton et al., PLoS ONE, 2013

by Rachel R. Atherton, Jane E. Williams, Jonathan C. K. Wells, Mary S. Fewtrell Background Clinical application of body composition (BC) measurements for individual children has been limited by lack of appropriate reference data. Objectives (1) To compare fat mass (FM) and fat free mass ...

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Hypoxia Stimulates the EMT of Gastric Cancer Cells through Autocrine TGFβ Signaling

17.05.2013 | Junko Matsuoka et al., PLoS ONE, 2013

by Junko Matsuoka, Masakazu Yashiro, Yosuke Doi, Yuhiko Fuyuhiro, Yukihiro Kato, Osamu Shinto, Satoru Noda, Shinichiro Kashiwagi, Naoki Aomatsu, Toshiki Hirakawa, Tsuyoshi Hasegawa, Kiyoshi Shimizu, Toshiyuki Shimizu, Atsushi Miwa, Nobuya Yamada, Tetsuji Sawada, Kosei Hirakawa Epithelial ...

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Overexpression of a MADS-Box Gene from Birch (Betula platyphylla) Promotes Flowering and Enhances Chloroplast Development in Transgenic Tobacco

17.05.2013 | Guan-Zheng Qu et al., PLoS ONE, 2013

by Guan-Zheng Qu, Tangchun Zheng, Guifeng Liu, Wenjie Wang, Lina Zang, Huanzhen Liu, Chuanping Yang In this study, a MADS-box gene (BpMADS), which is an ortholog of AP1 from Arabidopsis, was isolated from birch (Betula platyphylla). Transgenic Arabidopsis containing a BpMADS promoter::GUS ...

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Prognostic Risk Estimates of Patients with Multiple Sclerosis and Their Physicians: Comparison to an Online Analytical Risk Counseling Tool

17.05.2013 | Christoph Heesen et al., PLoS ONE, 2013

by Christoph Heesen, Wolfgang Gaissmaier, Franziska Nguyen, Jan-Patrick Stellmann, Jürgen Kasper, Sascha Köpke, Christian Lederer, Anneke Neuhaus, Martin Daumer Background Prognostic counseling in multiple sclerosis (MS) is difficult because of the high variability of disease progression. ...

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The Antimicrobial Compound Xantholysin Defines a New Group of Pseudomonas Cyclic Lipopeptides

17.05.2013 | Wen Li et al., PLoS ONE, 2013

by Wen Li, Hassan Rokni-Zadeh, Matthias De Vleeschouwer, Maarten G. K. Ghequire, Davy Sinnaeve, Guan-Lin Xie, Jef Rozenski, Annemieke Madder, José C. Martins, René De Mot The rhizosphere isolate Pseudomonas putida BW11M1 produces a mixture of cyclic lipopeptide congeners, designated ...

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Phylogenetic and Recombination Analysis of Tomato Spotted Wilt Virus

17.05.2013 | Sen Lian et al., PLoS ONE, 2013

by Sen Lian, Jong-Seung Lee, Won Kyong Cho, Jisuk Yu, Mi-Kyeong Kim, Hong-Soo Choi, Kook-Hyung Kim Tomato spotted wilt virus (TSWV) severely damages and reduces the yield of many economically important plants worldwide. In this study, we determined the whole-genome sequences of 10 TSWV ...

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