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2.846 Aktuelle Fachpublikationen in PLoS Genetics

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Turning Escherichia coli into a Frataxin-Dependent Organism

21.05.2015 | Béatrice Roche et al., PLoS Genetics, 2015

by Béatrice Roche, Rym Agrebi, Allison Huguenot, Sandrine Ollagnier de Choudens, Frédéric Barras, Béatrice Py Fe-S bound proteins are ubiquitous and contribute to most basic cellular processes. A defect in the ISC components catalyzing Fe-S cluster biogenesis leads to drastic phenotypes in both ...

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Trading Places—Switching Frataxin Function by a Single Amino Acid Substitution within the [Fe-S] Cluster Assembly Scaffold

21.05.2015 | Dennis R. Dean et al., PLoS Genetics, 2015

by Dennis R. Dean, Patricia C. Dos Santos

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Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation

20.05.2015 | Naina Phadnis et al., PLoS Genetics, 2015

by Naina Phadnis, Lubos Cipak, Silvia Polakova, Randy W. Hyppa, Ingrid Cipakova, Dorothea Anrather, Lucia Karvaiova, Karl Mechtler, Gerald R. Smith, Juraj Gregan Proper meiotic chromosome segregation, essential for sexual reproduction, requires timely formation and removal of sister chromatid ...

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CTXφ Replication Depends on the Histone-Like HU Protein and the UvrD Helicase

20.05.2015 | Eriel Martínez et al., PLoS Genetics, 2015

by Eriel Martínez, Evelyne Paly, François-Xavier Barre The Vibrio cholerae bacterium is the agent of cholera. The capacity to produce the cholera toxin, which is responsible for the deadly diarrhea associated with cholera epidemics, is encoded in the genome of a filamentous phage, CTXφ. ...

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Y Fuse? Sex Chromosome Fusions in Fishes and Reptiles

20.05.2015 | Matthew W. Pennell et al., PLoS Genetics, 2015

by Matthew W. Pennell, Mark Kirkpatrick, Sarah P. Otto, Jana C. Vamosi, Catherine L. Peichel, Nicole Valenzuela, Jun Kitano Chromosomal fusion plays a recurring role in the evolution of adaptations and reproductive isolation among species, yet little is known of the evolutionary drivers of ...

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MicroRNA-Dependent Transcriptional Silencing of Transposable Elements in Drosophila Follicle Cells

19.05.2015 | Bruno Mugat et al., PLoS Genetics, 2015

by Bruno Mugat, Abdou Akkouche, Vincent Serrano, Claudia Armenise, Blaise Li, Christine Brun, Tudor A. Fulga, David Van Vactor, Alain Pélisson, Séverine Chambeyron RNA interference-related silencing mechanisms concern very diverse and distinct biological processes, from gene regulation (via the ...

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A Unique Virulence Gene Occupies a Principal Position in Immune Evasion by the Malaria Parasite Plasmodium falciparum

19.05.2015 | Uchechi E. Ukaegbu et al., PLoS Genetics, 2015

by Uchechi E. Ukaegbu, Xu Zhang, Adina R. Heinberg, Mamadou Wele, Qijun Chen, Kirk W. Deitsch Mutually exclusive gene expression, whereby only one member of a multi-gene family is selected for activation, is used by the malaria parasite Plasmodium falciparum to escape the human immune system ...

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Minor Type IV Collagen α5 Chain Promotes Cancer Progression through Discoidin Domain Receptor-1

19.05.2015 | Qian Xiao et al., PLoS Genetics, 2015

by Qian Xiao, Yan Jiang, Qingbo Liu, Jiao Yue, Chunying Liu, Xiaotong Zhao, Yuemei Qiao, Hongbin Ji, Jianfeng Chen, Gaoxiang Ge Type IV collagens (Col IV), components of basement membrane, are essential in the maintenance of tissue integrity and proper function. Alteration of Col IV is related ...

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Promotion of Bone Morphogenetic Protein Signaling by Tetraspanins and Glycosphingolipids

15.05.2015 | Zhiyu Liu et al., PLoS Genetics, 2015

by Zhiyu Liu, Herong Shi, Lindsey C. Szymczak, Taner Aydin, Sijung Yun, Katharine Constas, Arielle Schaeffer, Sinthu Ranjan, Saad Kubba, Emad Alam, Devin E. McMahon, Jingpeng He, Neta Shwartz, Chenxi Tian, Yevgeniy Plavskin, Amanda Lindy, Nimra Amir Dad, Sunny Sheth, Nirav M. Amin, Stephanie ...

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Biological Significance of Photoreceptor Photocycle Length: VIVID Photocycle Governs the Dynamic VIVID-White Collar Complex Pool Mediating Photo-adaptation and Response to Changes in Light Intensity

15.05.2015 | Arko Dasgupta et al., PLoS Genetics, 2015

by Arko Dasgupta, Chen-Hui Chen, ChangHwan Lee, Amy S. Gladfelter, Jay C. Dunlap, Jennifer J. Loros Most organisms on earth sense light through the use of chromophore-bearing photoreceptive proteins with distinct and characteristic photocycle lengths, yet the biological significance of this ...

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