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511 Aktuelle Fachpublikationen in PLoS Genetics

mit folgenden Suchkriterien:

Ectodysplasin/NF-κB Promotes Mammary Cell Fate via Wnt/β-catenin Pathway

18.11.2015 | Maria Voutilainen et al., PLoS Genetics, 2015

by Maria Voutilainen, Päivi H. Lindfors, Ewelina Trela, Darielle Lönnblad, Vera Shirokova, Teresa Elo, Elisa Rysti, Ruth Schmidt-Ullrich, Pascal Schneider, Marja L. Mikkola Mammary gland development commences during embryogenesis with the establishment of a species typical number of mammary ...


Enhancer Runaway and the Evolution of Diploid Gene Expression

12.11.2015 | Frédéric Fyon et al., PLoS Genetics, 2015

by Frédéric Fyon, Aurélie Cailleau, Thomas Lenormand Evidence is mounting that the evolution of gene expression plays a major role in adaptation and speciation. Understanding the evolution of gene regulatory regions is indeed an essential step in linking genotypes and phenotypes and in ...


Dynamics of Transcription Factor Binding Site Evolution

06.11.2015 | Murat Tuğrul et al., PLoS Genetics, 2015

by Murat Tuğrul, Tiago Paixão, Nicholas H. Barton, Gašper Tkačik Evolution of gene regulation is crucial for our understanding of the phenotypic differences between species, populations and individuals. Sequence-specific binding of transcription factors to the regulatory regions on the DNA is a ...


Drosophila Nipped-B Mutants Model Cornelia de Lange Syndrome in Growth and Behavior

06.11.2015 | Yaning Wu et al., PLoS Genetics, 2015

by Yaning Wu, Maria Gause, Dongbin Xu, Ziva Misulovin, Cheri A. Schaaf, Ramya C. Mosarla, Elizabeth Mannino, Megan Shannon, Emily Jones, Mi Shi, Wen-Feng Chen, Olivia L. Katz, Amita Sehgal, Thomas A. Jongens, Ian D. Krantz, Dale Dorsett Individuals with Cornelia de Lange Syndrome (CdLS) display ...


UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid Development

06.11.2015 | Yafei Cai et al., PLoS Genetics, 2015

by Yafei Cai, Wenhu Pi, Satish Sivaprakasam, Xiaobin Zhu, Mingsheng Zhang, Jijun Chen, Levi Makala, Chunwan Lu, Jianchu Wu, Yong Teng, Betty Pace, Dorothy Tuan, Nagendra Singh, Honglin Li The Ufm1 conjugation system is an ubiquitin-like modification system that consists of Ufm1, Uba5 (E1), Ufc1 ...


Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape

04.11.2015 | Scarlet S. Shell et al., PLoS Genetics, 2015

by Scarlet S. Shell, Jing Wang, Pascal Lapierre, Mushtaq Mir, Michael R. Chase, Margaret M. Pyle, Richa Gawande, Rushdy Ahmad, David A. Sarracino, Thomas R. Ioerger, Sarah M. Fortune, Keith M. Derbyshire, Joseph T. Wade, Todd A. Gray RNA-seq technologies have provided significant insight into ...


Tissue-Specific Effects of Reduced β-catenin Expression on Adenomatous Polyposis Coli Mutation-Instigated Tumorigenesis in Mouse Colon and Ovarian Epithelium

03.11.2015 | Ying Feng et al., PLoS Genetics, 2015

by Ying Feng, Naoya Sakamoto, Rong Wu, Jie-yu Liu, Alexandra Wiese, Maranne E. Green, Megan Green, Aytekin Akyol, Badal C. Roy, Yali Zhai, Kathleen R. Cho, Eric R. Fearon Adenomatous polyposis coli (APC) inactivating mutations are present in most human colorectal cancers and some other cancers. ...


Mapping of Craniofacial Traits in Outbred Mice Identifies Major Developmental Genes Involved in Shape Determination

02.11.2015 | Luisa F. Pallares et al., PLoS Genetics, 2015

by Luisa F. Pallares, Peter Carbonetto, Shyam Gopalakrishnan, Clarissa C. Parker, Cheryl L. Ackert-Bicknell, Abraham A. Palmer, Diethard Tautz The vertebrate cranium is a prime example of the high evolvability of complex traits. While evidence of genes and developmental pathways underlying ...


SCARN a Novel Class of SCAR Protein That Is Required for Root-Hair Infection during Legume Nodulation

30.10.2015 | Liping Qiu et al., PLoS Genetics, 2015

by Liping Qiu, Jie-shun Lin, Ji Xu, Shusei Sato, Martin Parniske, Trevor L. Wang, J. Allan Downie, Fang Xie Rhizobial infection of legume root hairs requires a rearrangement of the actin cytoskeleton to enable the establishment of plant-made infection structures called infection threads. In the ...


The RNAPII-CTD Maintains Genome Integrity through Inhibition of Retrotransposon Gene Expression and Transposition

23.10.2015 | Maria J. Aristizabal et al., PLoS Genetics, 2015

by Maria J. Aristizabal, Gian Luca Negri, Michael S. Kobor RNA polymerase II (RNAPII) contains a unique C-terminal domain that is composed of heptapeptide repeats and which plays important regulatory roles during gene expression. RNAPII is responsible for the transcription of most ...


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