13.06.2013 | Mona Hosseini et al., PLoS Genetics, 2013

by Mona Hosseini, Leo Goodstadt, Jim R. Hughes, Monika S. Kowalczyk, Marco de Gobbi, Georg W. Otto, Richard R. Copley, Richard Mott, Douglas R. Higgs, Jonathan Flint Variation at regulatory elements, identified through hypersensitivity to digestion by DNase I, is believed to contribute to ...

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13.06.2013 | Natalie Saini et al., PLoS Genetics, 2013

by Natalie Saini, Yu Zhang, Yuri Nishida, Ziwei Sheng, Shilpa Choudhury, Piotr Mieczkowski, Kirill S. Lobachev DNA sequences capable of adopting non-canonical secondary structures have been associated with gross-chromosomal rearrangements in humans and model organisms. Previously, we have ...

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13.06.2013 | María Isabel Rodríguez et al., PLoS Genetics, 2013

by María Isabel Rodríguez, Andreína Peralta-Leal, Francisco O'Valle, José Manuel Rodriguez-Vargas, Ariannys Gonzalez-Flores, Jara Majuelos-Melguizo, Laura López, Santiago Serrano, Antonio García de Herreros, Juan Carlos Rodríguez-Manzaneque, Rubén Fernández, Raimundo G. del Moral, José ...

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13.06.2013 | Nathalie Caruso et al., PLoS Genetics, 2013

by Nathalie Caruso, Balàzs Herberth, Marc Bartoli, Francesca Puppo, Julie Dumonceaux, Angela Zimmermann, Simon Denadai, Marie Lebossé, Stephane Roche, Linda Geng, Frederique Magdinier, Shahram Attarian, Rafaelle Bernard, Flavio Maina, Nicolas Levy, Françoise Helmbacher Generation of ...

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13.06.2013 | Nathalie Colombié et al., PLoS Genetics, 2013

by Nathalie Colombié, A. Agata Głuszek, Ana M. Meireles, Hiroyuki Ohkura In the oocytes of many animals including humans, the meiotic spindle assembles without centrosomes. It is still unclear how multiple pathways contribute to spindle microtubule assembly, and whether they are regulated ...

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13.06.2013 | Urko M. Marigorta et al., PLoS Genetics, 2013

by Urko M. Marigorta, Arcadi Navarro Genome-wide association studies (GWAS) have detected many disease associations. However, the reported variants tend to explain small fractions of risk, and there are doubts about issues such as the portability of findings over different ethnic groups or ...

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13.06.2013 | Daniel Croll et al., PLoS Genetics, 2013

by Daniel Croll, Marcello Zala, Bruce A. McDonald Chromosomal rearrangements are a major driver of eukaryotic genome evolution, affecting speciation, pathogenicity and cancer progression. Changes in chromosome structure are often initiated by mis-repair of double-strand breaks in the DNA. ...

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13.06.2013 | Mark J. Banfield et al., PLoS Genetics, 2013

by Mark J. Banfield, Sophien Kamoun

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13.06.2013 | Jae Hoon Sul et al., PLoS Genetics, 2013

by Jae Hoon Sul, Buhm Han, Chun Ye, Ted Choi, Eleazar Eskin Gene expression data, in conjunction with information on genetic variants, have enabled studies to identify expression quantitative trait loci (eQTLs) or polymorphic locations in the genome that are associated with expression ...

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13.06.2013 | Rays H. Y. Jiang et al., PLoS Genetics, 2013

by Rays H. Y. Jiang, Irene de Bruijn, Brian J. Haas, Rodrigo Belmonte, Lars Löbach, James Christie, Guido van den Ackerveken, Arnaud Bottin, Vincent Bulone, Sara M. Díaz-Moreno, Bernard Dumas, Lin Fan, Elodie Gaulin, Francine Govers, Laura J. Grenville-Briggs, Neil R. Horner, Joshua Z. ...

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