15.05.2013 | Abdul‐Lateef Molan, Zhuojian Liu, Gabriel Plimmer, Phytotherapy Research, 2013

The purpose of this study was to determine in healthy humans whether First Leaf (FL; composed of blackcurrant extract powder, lactoferrin and lutein) and Cassis Anthomix 30 (CAM30; blackcurrant extract powder) can positively modify the colonic microbiota by enhancing the growth of the ...

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15.05.2013 | Hiroshige Chiba, Hyounju Kim, Akiyo Matsumoto, Satoko Akiyama, Yoshiko Ishimi, Kazuharu Suzuki, Mariko Uehara, Phytotherapy Research, 2013

Abstract The purpose of this study was to examine whether hesperidin inhibits bone loss in androgen‐deficient male mice. Male ddY mice aged 7 weeks underwent either a sham operation or orchidectomy (ORX) and were divided into five groups: a sham‐operated group fed a control diet (Sham) ...

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15.05.2013 | Ciddi Veeresham, Ajmeera Rama Rao, Kaleab Asres, Phytotherapy Research, 2013

Diabetic complications are attributed to hyperglycaemic condition which is in turn associated with the polyol pathway and advanced glycation end products. Aldose reductase (AR) is the principal enzyme of polyol pathway which plays a vital role in the development of diabetic complications. ...

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09.05.2013 | Maghbooli Mehdi, Golipour Farhad, Moghimi Esfandabadi Alireza, Yousefi Mehran, Phytotherapy Research, 2013

Frequency and torment caused by migraines direct patients toward a variety of remedies. Few studies to date have proposed ginger derivates for migraine relief. This study aims to evaluate the efficacy of ginger in the ablation of common migraine attack in comparison to sumatriptan therapy. ...

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03.05.2013 | Patrick Kwok‐Kin Lai, Judy Yuet‐Wa Chan, Shi‐Biao Wu, Ling Cheng, Grace Ka‐Wai Ho, Ching‐Po Lau, Edward J. Kennelly, ..., Phytotherapy Research, 2013

The root of Astragalus membranaceus (AR), which has been widely used in Traditional Chinese herbal formulae for treating foot ulcer, was found to exhibit anti‐inflammatory property, but its molecular mechanism still remains unknown. We previously identified the anti‐inflammatory ...

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03.05.2013 | Song Hyo Sook, Hyo‐Jung Lee, Ji‐Hyun Kim, EunJung Sohn, Ji Hoon Jung, Bonglee Kim, Jin‐Hyoung Kim, Soo‐Jin Jeong, Su ..., Phytotherapy Research, 2013

Although beta‐sitosterol has been well known to have anti‐tumor activity in liver, lung, colon, stomach, breast and prostate cancers via cell cycle arrest and apoptosis induction, the underlying mechanism of anti‐cancer effect of beta‐sitosterol in multiple myeloma cells was never ...

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03.05.2013 | Julino A. R. Soares Neto, José Carlos F. Galduróz, Luis Carlos Marques, Edna Tomiko Kato, Thiago Macrini, Eliana Rod ..., Phytotherapy Research, 2013

The present study aimed to investigate the occurrence of adverse reactions (ADRs) related to herbal products (HPs), which are purchased over‐the‐counter for self‐treatment, reported by 100 users. Samples of the HPs related to those ADRs were purchased for their pharmacobotanical ...

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29.04.2013 | Murlidhar Meghwal, T. K. Goswami, Phytotherapy Research, 2013

Black pepper (Piper nigrum L.) is a very widely used spice, known for its pungent constituent piperine. However, in addition to its culinary uses, pepper has important medicinal and preservative properties, and, more recently, piperine has been shown to have fundamental effects on ...

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26.04.2013 | Boel De Paepe, Katrien Vandemeulebroecke, Joél Smet, Arnaud Vanlander, Sara Seneca, Willy Lissens, Johan LK Van Hove ..., Phytotherapy Research, 2013

Few therapeutic options are available to patients with oxidative phosphorylation disorders. Administering pharmacological agents that are able to stimulate mitochondrial biogenesis have been put forward as a possible treatment, yet the approach remains in need of thorough testing. We ...

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26.04.2013 | Fang Lu, Lei Liu, Dong‐hua Yu, Xu‐zhao Li, Qi Zhou, Shu‐min Liu, Phytotherapy Research, 2013

Rhizoma Dioscoreae Nipponicae (RDN) is a widely used traditional Chinese herb, which is used to treat arthroncus, arthrodynia and arthritis. As is known to us, inflammatory mechanisms have played an important role in the occurrence, course and prognosis of gouty arthritis (GA). The aim of ...

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