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1.019 Aktuelle Fachpublikationen in Nature Medicine

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Hugging tight in Huntington's

07.03.2011 | Ashu Johri; Rajnish K Chaturvedi; M Flint Beal, Nature Medicine, 2011

Hugging tight in Huntington's Nature Medicine 17, 245 (2011). doi:10.1038/nm0311-245 Authors: Ashu Johri, Rajnish K Chaturvedi & M Flint Beal Mitochondrial fission-fusion and trafficking are altered in the fatal neurodegenerative disorder Huntington's disease. Huntingtin is now shown to ...

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Despite steep costs, payments for new cancer drugs make economic sense

07.03.2011 | Frank R Lichtenberg, Nature Medicine, 2011

Despite steep costs, payments for new cancer drugs make economic sense Nature Medicine 17, 244 (2011). doi:10.1038/nm0311-244 Authors: Frank R Lichtenberg Cancer drugs have become more expensive over the past few years, leading many people to question whether the treatments are really ...

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Cancer epigenetics reaches mainstream oncology

07.03.2011 | Manuel Rodríguez-Paredes; Manel Esteller, Nature Medicine, 2011

Cancer epigenetics reaches mainstream oncology Nature Medicine 17, 330 (2011). doi:10.1038/nm.2305 Authors: Manuel Rodríguez-Paredes & Manel Esteller

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Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

07.03.2011 | Mina J Bissell; William C Hines, Nature Medicine, 2011

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression Nature Medicine 17, 320 (2011). doi:10.1038/nm.2328 Authors: Mina J Bissell & William C Hines

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Cancer genomics: from discovery science to personalized medicine

07.03.2011 | Lynda Chin; Jannik N Andersen; P Andrew Futreal, Nature Medicine, 2011

Cancer genomics: from discovery science to personalized medicine Nature Medicine 17, 297 (2011). doi:10.1038/nm.2323 Authors: Lynda Chin, Jannik N Andersen & P Andrew Futreal

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Research Highlights

07.03.2011 | Victoria Aranda; Alison Farrell; Carolina Pola; Meera Swami, Nature Medicine, 2011

Research Highlights Nature Medicine 17, 294 (2011). doi:10.1038/nm0311-294 Author: Victoria Aranda, Alison Farrell, Carolina Pola & Meera Swami

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Metabolism unhinged: IDH mutations in cancer

07.03.2011 | John R Prensner; Arul M Chinnaiyan, Nature Medicine, 2011

Metabolism unhinged: IDH mutations in cancer Nature Medicine 17, 291 (2011). doi:10.1038/nm0311-291 Authors: John R Prensner & Arul M Chinnaiyan Recently characterized IDH1 and IDH2 mutations in leukemia and glioblastoma have introduced a fascinating cancer-specific role for metabolic ...

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Hunting ALK to feed targeted cancer therapy

07.03.2011 | Anton Wellstein; Jeffrey A Toretsky, Nature Medicine, 2011

Hunting ALK to feed targeted cancer therapy Nature Medicine 17, 290 (2011). doi:10.1038/nm0311-290 Authors: Anton Wellstein & Jeffrey A Toretsky Neuroblastoma is a fatal childhood cancer, but lack of knowledge about the underlying causative genes has hampered the development of effective ...

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Resistance, epigenetics and the cancer ecosystem

07.03.2011 | Stephen B Baylin, Nature Medicine, 2011

Resistance, epigenetics and the cancer ecosystem Nature Medicine 17, 288 (2011). doi:10.1038/nm0311-288 Authors: Stephen B Baylin Therapeutic resistance is a key roadblock to effective cancer treatment and can occur through various mechanisms. A recent study characterized a previously ...

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Targeting RAF: trials and tribulations

07.03.2011 | Julian Downward, Nature Medicine, 2011

Targeting RAF: trials and tribulations Nature Medicine 17, 286 (2011). doi:10.1038/nm0311-286 Authors: Julian Downward Although the rapid development of drug resistance is a known problem with targeted cancer therapies, recent studies have uncovered other surprises with RAF kinase ...

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